184 related articles for article (PubMed ID: 23840331)
1. Pharmacologic Approach to Defective Protein Trafficking in the E637K-hERG Mutant with PD-118057 and Thapsigargin.
Mao H; Lu X; Karush JM; Huang X; Yang X; Ba Y; Wang Y; Liu N; Zhou J; Lian J
PLoS One; 2013; 8(6):e65481. PubMed ID: 23840331
[TBL] [Abstract][Full Text] [Related]
2. RNA interference targeting E637K mutation rescues hERG channel currents and restores its kinetic properties.
Lu X; Yang X; Huang X; Huang C; Sun HH; Jin L; Xu W; Mao H; Guo J; Zhou J; Lian J
Heart Rhythm; 2013 Jan; 10(1):128-36. PubMed ID: 23022675
[TBL] [Abstract][Full Text] [Related]
3. Characterization of a novel missense mutation E637K in the pore-S6 loop of HERG in a patient with long QT syndrome.
Hayashi K; Shimizu M; Ino H; Yamaguchi M; Mabuchi H; Hoshi N; Higashida H
Cardiovasc Res; 2002 Apr; 54(1):67-76. PubMed ID: 12062363
[TBL] [Abstract][Full Text] [Related]
4. Trafficking-deficient G572R-hERG and E637K-hERG activate stress and clearance pathways in endoplasmic reticulum.
Wang Y; Huang X; Zhou J; Yang X; Li D; Mao H; Sun HH; Liu N; Lian J
PLoS One; 2012; 7(1):e29885. PubMed ID: 22242185
[TBL] [Abstract][Full Text] [Related]
5. Novel characteristics of a trafficking-defective G572R-hERG channel linked to hereditary long QT syndrome.
Lian J; Huang N; Zhou J; Ge S; Huang X; Huo J; Liu L; Xu W; Zhang S; Yang X; Zhou J; Huang C
Can J Cardiol; 2010 Oct; 26(8):417-22. PubMed ID: 20931094
[TBL] [Abstract][Full Text] [Related]
6. Thapsigargin selectively rescues the trafficking defective LQT2 channels G601S and F805C.
Delisle BP; Anderson CL; Balijepalli RC; Anson BD; Kamp TJ; January CT
J Biol Chem; 2003 Sep; 278(37):35749-54. PubMed ID: 12837749
[TBL] [Abstract][Full Text] [Related]
7. Most LQT2 mutations reduce Kv11.1 (hERG) current by a class 2 (trafficking-deficient) mechanism.
Anderson CL; Delisle BP; Anson BD; Kilby JA; Will ML; Tester DJ; Gong Q; Zhou Z; Ackerman MJ; January CT
Circulation; 2006 Jan; 113(3):365-73. PubMed ID: 16432067
[TBL] [Abstract][Full Text] [Related]
8. Differential Effects of Remdesivir and Lumacaftor on Homomeric and Heteromeric hERG Channels.
Campagna N; Wall E; Lee K; Guo J; Li W; Yang T; Baranchuk A; El-Diasty M; Zhang S
Mol Pharmacol; 2023 Oct; 104(4):164-173. PubMed ID: 37419691
[TBL] [Abstract][Full Text] [Related]
9. Properties of WT and mutant hERG K(+) channels expressed in neonatal mouse cardiomyocytes.
Lin EC; Holzem KM; Anson BD; Moungey BM; Balijepalli SY; Tester DJ; Ackerman MJ; Delisle BP; Balijepalli RC; January CT
Am J Physiol Heart Circ Physiol; 2010 Jun; 298(6):H1842-9. PubMed ID: 20363883
[TBL] [Abstract][Full Text] [Related]
10. The role and mechanism of chaperones Calnexin/Calreticulin in which ALLN selectively rescues the trafficking defective of HERG-A561V mutation.
Wang Y; Shen T; Fang P; Zhou J; Lou K; Cen Z; Qian H; Zhou J; Liu N; Lian J
Biosci Rep; 2018 Oct; 38(5):. PubMed ID: 29752336
[TBL] [Abstract][Full Text] [Related]
11. Serine mutation of a conserved threonine in the hERG K
Al-Moubarak E; Zhang Y; Dempsey CE; Zhang H; Harmer SC; Hancox JC
Biochem Biophys Res Commun; 2020 Jun; 526(4):1085-1091. PubMed ID: 32321643
[TBL] [Abstract][Full Text] [Related]
12. A novel mutation in KCNH2 yields loss-of-function of hERG potassium channel in long QT syndrome 2.
Gu K; Qian D; Qin H; Cui C; Fernando WCHA; Wang D; Wang J; Cao K; Chen M
Pflugers Arch; 2021 Feb; 473(2):219-229. PubMed ID: 33449212
[TBL] [Abstract][Full Text] [Related]
13. HERG-F463L potassium channels linked to long QT syndrome reduce I(Kr) current by a trafficking-deficient mechanism.
Yang HT; Sun CF; Cui CC; Xue XL; Zhang AF; Li HB; Wang DQ; Shu J
Clin Exp Pharmacol Physiol; 2009 Aug; 36(8):822-7. PubMed ID: 19215240
[TBL] [Abstract][Full Text] [Related]
14. [The mechanistic rote of KCNH2 gene L413P and L559H mutations in long QT syndrome].
Li CL; Hu DY; Liu WL; Qi SY; Wang HT; Li L; Gong QM; Zhou ZF
Zhonghua Nei Ke Za Zhi; 2007 Oct; 46(10):838-41. PubMed ID: 18218237
[TBL] [Abstract][Full Text] [Related]
15. Pharmacological correction of long QT-linked mutations in KCNH2 (hERG) increases the trafficking of Kv11.1 channels stored in the transitional endoplasmic reticulum.
Smith JL; Reloj AR; Nataraj PS; Bartos DC; Schroder EA; Moss AJ; Ohno S; Horie M; Anderson CL; January CT; Delisle BP
Am J Physiol Cell Physiol; 2013 Nov; 305(9):C919-30. PubMed ID: 23864605
[TBL] [Abstract][Full Text] [Related]
16. Correction of defective protein trafficking of a mutant HERG potassium channel in human long QT syndrome. Pharmacological and temperature effects.
Zhou Z; Gong Q; January CT
J Biol Chem; 1999 Oct; 274(44):31123-6. PubMed ID: 10531299
[TBL] [Abstract][Full Text] [Related]
17. The G604S-hERG mutation alters the biophysical properties and exerts a dominant-negative effect on expression of hERG channels in HEK293 cells.
Huo J; Zhang Y; Huang N; Liu P; Huang C; Guo X; Jiang W; Zhou N; Grace A; Huang CL; Ma A
Pflugers Arch; 2008 Aug; 456(5):917-28. PubMed ID: 18386051
[TBL] [Abstract][Full Text] [Related]
18. Restoration of mutant hERG stability by inhibition of HDAC6.
Li P; Kurata Y; Endang M; Ninomiya H; Higaki K; Taufiq F; Morikawa K; Shirayoshi Y; Horie M; Hisatome I
J Mol Cell Cardiol; 2018 Feb; 115():158-169. PubMed ID: 29355491
[TBL] [Abstract][Full Text] [Related]
19. Rescue of aberrant gating by a genetically encoded PAS (Per-Arnt-Sim) domain in several long QT syndrome mutant human ether-รก-go-go-related gene potassium channels.
Gianulis EC; Trudeau MC
J Biol Chem; 2011 Jun; 286(25):22160-9. PubMed ID: 21536673
[TBL] [Abstract][Full Text] [Related]
20. Electrophysiological characterization of the modified hERG
Zhang Y; Dempsey CE; Hancox JC
Physiol Rep; 2020 Oct; 8(20):e14568. PubMed ID: 33091232
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
