184 related articles for article (PubMed ID: 23844627)
1. Predictive model for epoxide hydrolase-generated stereochemistry in the biosynthesis of nine-membered enediyne antitumor antibiotics.
Horsman GP; Lechner A; Ohnishi Y; Moore BS; Shen B
Biochemistry; 2013 Aug; 52(31):5217-24. PubMed ID: 23844627
[TBL] [Abstract][Full Text] [Related]
2. Characterization of the SgcF epoxide hydrolase supporting an (R)-vicinal diol intermediate for enediyne antitumor antibiotic C-1027 biosynthesis.
Lin S; Horsman GP; Chen Y; Li W; Shen B
J Am Chem Soc; 2009 Nov; 131(45):16410-7. PubMed ID: 19856960
[TBL] [Abstract][Full Text] [Related]
3. Characterization of the epoxide hydrolase NcsF2 from the neocarzinostatin biosynthetic gene cluster.
Lin S; Horsman GP; Shen B
Org Lett; 2010 Sep; 12(17):3816-9. PubMed ID: 20704329
[TBL] [Abstract][Full Text] [Related]
4. Cloning and sequencing of the kedarcidin biosynthetic gene cluster from Streptoalloteichus sp. ATCC 53650 revealing new insights into biosynthesis of the enediyne family of antitumor antibiotics.
Lohman JR; Huang SX; Horsman GP; Dilfer PE; Huang T; Chen Y; Wendt-Pienkowski E; Shen B
Mol Biosyst; 2013 Mar; 9(3):478-91. PubMed ID: 23360970
[TBL] [Abstract][Full Text] [Related]
5. Identification and catalytic properties of new epoxide hydrolases from the genomic data of soil bacteria.
Stojanovski G; Dobrijevic D; Hailes HC; Ward JM
Enzyme Microb Technol; 2020 Sep; 139():109592. PubMed ID: 32732040
[TBL] [Abstract][Full Text] [Related]
6. Mutation of an atypical oxirane oxyanion hole improves regioselectivity of the α/β-fold epoxide hydrolase Alp1U.
Zhang L; De BC; Zhang W; Mándi A; Fang Z; Yang C; Zhu Y; Kurtán T; Zhang C
J Biol Chem; 2020 Dec; 295(50):16987-16997. PubMed ID: 33004437
[TBL] [Abstract][Full Text] [Related]
7. 4-methylideneimidazole-5-one-containing aminomutases in enediyne biosynthesis.
Lohman JR; Shen B
Methods Enzymol; 2012; 516():299-319. PubMed ID: 23034235
[TBL] [Abstract][Full Text] [Related]
8. Structural Insights into the Free-Standing Condensation Enzyme SgcC5 Catalyzing Ester-Bond Formation in the Biosynthesis of the Enediyne Antitumor Antibiotic C-1027.
Chang CY; Lohman JR; Huang T; Michalska K; Bigelow L; Rudolf JD; Jedrzejczak R; Yan X; Ma M; Babnigg G; Joachimiak A; Phillips GN; Shen B
Biochemistry; 2018 Jun; 57(23):3278-3288. PubMed ID: 29533601
[TBL] [Abstract][Full Text] [Related]
9. Crystal structure of SgcJ, an NTF2-like superfamily protein involved in biosynthesis of the nine-membered enediyne antitumor antibiotic C-1027.
Huang T; Chang CY; Lohman JR; Rudolf JD; Kim Y; Chang C; Yang D; Ma M; Yan X; Crnovcic I; Bigelow L; Clancy S; Bingman CA; Yennamalli RM; Babnigg G; Joachimiak A; Phillips GN; Shen B
J Antibiot (Tokyo); 2016 Oct; 69(10):731-740. PubMed ID: 27406907
[TBL] [Abstract][Full Text] [Related]
10. Resistance to Enediyne Antitumor Antibiotics by Sequestration.
Chang CY; Yan X; Crnovcic I; Annaval T; Chang C; Nocek B; Rudolf JD; Yang D; Hindra ; Babnigg G; Joachimiak A; Phillips GN; Shen B
Cell Chem Biol; 2018 Sep; 25(9):1075-1085.e4. PubMed ID: 29937405
[TBL] [Abstract][Full Text] [Related]
11. Biosynthesis of enediyne antitumor antibiotics.
Van Lanen SG; Shen B
Curr Top Med Chem; 2008; 8(6):448-59. PubMed ID: 18397168
[TBL] [Abstract][Full Text] [Related]
12. Production of octaketide polyenes by the calicheamicin polyketide synthase CalE8: implications for the biosynthesis of enediyne core structures.
Belecki K; Crawford JM; Townsend CA
J Am Chem Soc; 2009 Sep; 131(35):12564-6. PubMed ID: 19689130
[TBL] [Abstract][Full Text] [Related]
13. Substrate specificity of the adenylation enzyme SgcC1 involved in the biosynthesis of the enediyne antitumor antibiotic C-1027.
Van Lanen SG; Lin S; Dorrestein PC; Kelleher NL; Shen B
J Biol Chem; 2006 Oct; 281(40):29633-40. PubMed ID: 16887797
[TBL] [Abstract][Full Text] [Related]
14. A phosphopantetheinylating polyketide synthase producing a linear polyene to initiate enediyne antitumor antibiotic biosynthesis.
Zhang J; Van Lanen SG; Ju J; Liu W; Dorrestein PC; Li W; Kelleher NL; Shen B
Proc Natl Acad Sci U S A; 2008 Feb; 105(5):1460-5. PubMed ID: 18223152
[TBL] [Abstract][Full Text] [Related]
15. An epoxide hydrolase from endophytic Streptomyces shows unique structural features and wide biocatalytic activity.
Tormet-González GD; Wilson C; de Oliveira GS; Dos Santos JC; de Oliveira LG; Dias MVB
Acta Crystallogr D Struct Biol; 2020 Sep; 76(Pt 9):868-875. PubMed ID: 32876062
[TBL] [Abstract][Full Text] [Related]
16. Biosynthesis of the enediyne antitumor antibiotic C-1027.
Liu W; Christenson SD; Standage S; Shen B
Science; 2002 Aug; 297(5584):1170-3. PubMed ID: 12183628
[TBL] [Abstract][Full Text] [Related]
17. Laboratory evolution of an epoxide hydrolase - towards an enantioconvergent biocatalyst.
Kotik M; Archelas A; Faměrová V; Oubrechtová P; Křen V
J Biotechnol; 2011 Oct; 156(1):1-10. PubMed ID: 21854816
[TBL] [Abstract][Full Text] [Related]
18. Draft genome sequence of Streptomyces globisporus C-1027, which produces an antitumor antibiotic consisting of a nine-membered enediyne with a chromoprotein.
Wang L; Wang S; He Q; Yu T; Li Q; Hong B
J Bacteriol; 2012 Aug; 194(15):4144. PubMed ID: 22815456
[TBL] [Abstract][Full Text] [Related]
19. Genes for production of the enediyne antitumor antibiotic C-1027 in Streptomyces globisporus are clustered with the cagA gene that encodes the C-1027 apoprotein.
Liu W; Shen B
Antimicrob Agents Chemother; 2000 Feb; 44(2):382-92. PubMed ID: 10639366
[TBL] [Abstract][Full Text] [Related]
20. Characterization of the maduropeptin biosynthetic gene cluster from Actinomadura madurae ATCC 39144 supporting a unifying paradigm for enediyne biosynthesis.
Van Lanen SG; Oh TJ; Liu W; Wendt-Pienkowski E; Shen B
J Am Chem Soc; 2007 Oct; 129(43):13082-94. PubMed ID: 17918933
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
