BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

109 related articles for article (PubMed ID: 23844996)

  • 1. Local unfolding and aggregation mechanisms of SOD1: a Monte Carlo exploration.
    Bille A; Jónsson SÆ; Akke M; Irbäck A
    J Phys Chem B; 2013 Aug; 117(31):9194-202. PubMed ID: 23844996
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Dynamical roles of metal ions and the disulfide bond in Cu, Zn superoxide dismutase folding and aggregation.
    Ding F; Dokholyan NV
    Proc Natl Acad Sci U S A; 2008 Dec; 105(50):19696-701. PubMed ID: 19052230
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Denaturational stress induces formation of zinc-deficient monomers of Cu,Zn superoxide dismutase: implications for pathogenesis in amyotrophic lateral sclerosis.
    Mulligan VK; Kerman A; Ho S; Chakrabartty A
    J Mol Biol; 2008 Nov; 383(2):424-36. PubMed ID: 18761352
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Sequence and structural determinants of Cu, Zn superoxide dismutase aggregation.
    Khare SD; Wilcox KC; Gong P; Dokholyan NV
    Proteins; 2005 Nov; 61(3):617-32. PubMed ID: 16152647
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Calcium binding to gatekeeper residues flanking aggregation-prone segments underlies non-fibrillar amyloid traits in superoxide dismutase 1 (SOD1).
    Estácio SG; Leal SS; Cristóvão JS; Faísca PF; Gomes CM
    Biochim Biophys Acta; 2015 Feb; 1854(2):118-26. PubMed ID: 25463043
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Comparative structural and conformational studies on H43R and W32F mutants of copper-zinc superoxide dismutase by molecular dynamics simulation.
    Muneeswaran G; Kartheeswaran S; Muthukumar K; Dharmaraj CD; Karunakaran C
    Biophys Chem; 2014 Jan; 185():70-8. PubMed ID: 24369116
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Molecular dynamics using atomic-resolution structure reveal structural fluctuations that may lead to polymerization of human Cu-Zn superoxide dismutase.
    Strange RW; Yong CW; Smith W; Hasnain SS
    Proc Natl Acad Sci U S A; 2007 Jun; 104(24):10040-4. PubMed ID: 17548825
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Common dynamical signatures of familial amyotrophic lateral sclerosis-associated structurally diverse Cu, Zn superoxide dismutase mutants.
    Khare SD; Dokholyan NV
    Proc Natl Acad Sci U S A; 2006 Feb; 103(9):3147-52. PubMed ID: 16488975
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Small-molecule-mediated stabilization of familial amyotrophic lateral sclerosis-linked superoxide dismutase mutants against unfolding and aggregation.
    Ray SS; Nowak RJ; Brown RH; Lansbury PT
    Proc Natl Acad Sci U S A; 2005 Mar; 102(10):3639-44. PubMed ID: 15738401
    [TBL] [Abstract][Full Text] [Related]  

  • 10. ALS-causing SOD1 mutations promote production of copper-deficient misfolded species.
    Ip P; Mulligan VK; Chakrabartty A
    J Mol Biol; 2011 Jun; 409(5):839-52. PubMed ID: 21549128
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Aberrant zinc binding to immature conformers of metal-free copper-zinc superoxide dismutase triggers amorphous aggregation.
    Leal SS; Cristóvão JS; Biesemeier A; Cardoso I; Gomes CM
    Metallomics; 2015 Feb; 7(2):333-46. PubMed ID: 25554447
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Unfolding and aggregation of oxidized metal-deficient superoxide dismutase and isoflavone inhibition based on ion mobility mass spectrometry and ThT fluorescence assay.
    Bian X; Zhuang X; Zheng Z; Liu S; Liu Z; Song F
    Arch Biochem Biophys; 2022 Sep; 727():109306. PubMed ID: 35667444
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Mechanical probes of SOD1 predict systematic trends in metal and dimer affinity of ALS-associated mutants.
    Das A; Plotkin SS
    J Mol Biol; 2013 Mar; 425(5):850-74. PubMed ID: 23291526
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Unveiling the unfolding pathway of FALS associated G37R SOD1 mutant: a computational study.
    Milardi D; Pappalardo M; Grasso DM; La Rosa C
    Mol Biosyst; 2010 Jun; 6(6):1032-9. PubMed ID: 20485746
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Solvent sensitivity of protein aggregation in Cu, Zn superoxide dismutase: a molecular dynamics simulation study.
    Prakash A; Kumar V; Pandey P; Bharti DR; Vishwakarma P; Singh R; Hassan MI; Lynn AM
    J Biomol Struct Dyn; 2018 Aug; 36(10):2605-2617. PubMed ID: 28782426
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The rate and equilibrium constants for a multistep reaction sequence for the aggregation of superoxide dismutase in amyotrophic lateral sclerosis.
    Khare SD; Caplow M; Dokholyan NV
    Proc Natl Acad Sci U S A; 2004 Oct; 101(42):15094-9. PubMed ID: 15475574
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Metal-free superoxide dismutase forms soluble oligomers under physiological conditions: a possible general mechanism for familial ALS.
    Banci L; Bertini I; Durazo A; Girotto S; Gralla EB; Martinelli M; Valentine JS; Vieru M; Whitelegge JP
    Proc Natl Acad Sci U S A; 2007 Jul; 104(27):11263-7. PubMed ID: 17592131
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Lipid-associated aggregate formation of superoxide dismutase-1 is initiated by membrane-targeting loops.
    Chng CP; Strange RW
    Proteins; 2014 Nov; 82(11):3194-209. PubMed ID: 25212695
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Mutant SOD1 instability: implications for toxicity in amyotrophic lateral sclerosis.
    Tiwari A; Hayward LJ
    Neurodegener Dis; 2005; 2(3-4):115-27. PubMed ID: 16909016
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Heterodimer formation of wild-type and amyotrophic lateral sclerosis-causing mutant Cu/Zn-superoxide dismutase induces toxicity independent of protein aggregation.
    Witan H; Kern A; Koziollek-Drechsler I; Wade R; Behl C; Clement AM
    Hum Mol Genet; 2008 May; 17(10):1373-85. PubMed ID: 18211954
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.