These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

1117 related articles for article (PubMed ID: 23845848)

  • 1. Polycyclic aromatic hydrocarbons stimulate human CYP3A4 promoter activity via PXR.
    Luckert C; Ehlers A; Buhrke T; Seidel A; Lampen A; Hessel S
    Toxicol Lett; 2013 Oct; 222(2):180-8. PubMed ID: 23845848
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The induction of human UDP-glucuronosyltransferase 1A1 mediated through a distal enhancer module by flavonoids and xenobiotics.
    Sugatani J; Yamakawa K; Tonda E; Nishitani S; Yoshinari K; Degawa M; Abe I; Noguchi H; Miwa M
    Biochem Pharmacol; 2004 Mar; 67(5):989-1000. PubMed ID: 15104253
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Modulation of pregnane X receptor (PXR) and constitutive androstane receptor (CAR) activation by ursolic acid (UA) attenuates rifampin-isoniazid cytotoxicity.
    Chang HY; Chen CJ; Ma WC; Cheng WK; Lin YN; Lee YR; Chen JJ; Lim YP
    Phytomedicine; 2017 Dec; 36():37-49. PubMed ID: 29157826
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Polycyclic aromatic hydrocarbons activate CYP3A4 gene transcription through human pregnane X receptor.
    Kumagai T; Suzuki H; Sasaki T; Sakaguchi S; Miyairi S; Yamazoe Y; Nagata K
    Drug Metab Pharmacokinet; 2012; 27(2):200-6. PubMed ID: 22076448
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Valproic acid induces CYP3A4 and MDR1 gene expression by activation of constitutive androstane receptor and pregnane X receptor pathways.
    Cerveny L; Svecova L; Anzenbacherova E; Vrzal R; Staud F; Dvorak Z; Ulrichova J; Anzenbacher P; Pavek P
    Drug Metab Dispos; 2007 Jul; 35(7):1032-41. PubMed ID: 17392393
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Effects of atorvastatin metabolites on induction of drug-metabolizing enzymes and membrane transporters through human pregnane X receptor.
    Hoffart E; Ghebreghiorghis L; Nussler AK; Thasler WE; Weiss TS; Schwab M; Burk O
    Br J Pharmacol; 2012 Mar; 165(5):1595-608. PubMed ID: 21913896
    [TBL] [Abstract][Full Text] [Related]  

  • 7. PXR-mediated transcriptional activation of CYP3A4 by cryptotanshinone and tanshinone IIA.
    Yu C; Ye S; Sun H; Liu Y; Gao L; Shen C; Chen S; Zeng S
    Chem Biol Interact; 2009 Jan; 177(1):58-64. PubMed ID: 18805405
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Pregnane X receptor regulates the AhR/Cyp1A1 pathway and protects liver cells from benzo-[α]-pyrene-induced DNA damage.
    Cui H; Gu X; Chen J; Xie Y; Ke S; Wu J; Golovko A; Morpurgo B; Yan C; Phillips TD; Xie W; Luo J; Zhou Z; Tian Y
    Toxicol Lett; 2017 Jun; 275():67-76. PubMed ID: 28428138
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Genotoxic polycyclic aromatic hydrocarbon ortho-quinones generated by aldo-keto reductases induce CYP1A1 via nuclear translocation of the aryl hydrocarbon receptor.
    Burczynski ME; Penning TM
    Cancer Res; 2000 Feb; 60(4):908-15. PubMed ID: 10706104
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Endosulfan induces CYP2B6 and CYP3A4 by activating the pregnane X receptor.
    Casabar RC; Das PC; Dekrey GK; Gardiner CS; Cao Y; Rose RL; Wallace AD
    Toxicol Appl Pharmacol; 2010 Jun; 245(3):335-43. PubMed ID: 20361990
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Lower expression of HNF4α and PGC1α might impair rifampicin-mediated CYP3A4 induction under conditions where PXR is overexpressed in human fetal liver cells.
    Takezawa T; Matsunaga T; Aikawa K; Nakamura K; Ohmori S
    Drug Metab Pharmacokinet; 2012; 27(4):430-8. PubMed ID: 22333269
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Aryl hydrocarbon receptor-mediated activity of mutagenic polycyclic aromatic hydrocarbons determined using in vitro reporter gene assay.
    Machala M; Vondrácek J; Bláha L; Ciganek M; Neca JV
    Mutat Res; 2001 Oct; 497(1-2):49-62. PubMed ID: 11525907
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Carcinogenic polycyclic aromatic hydrocarbons induce CYP1A1 in human cells via a p53-dependent mechanism.
    Wohak LE; Krais AM; Kucab JE; Stertmann J; Øvrebø S; Seidel A; Phillips DH; Arlt VM
    Arch Toxicol; 2016 Feb; 90(2):291-304. PubMed ID: 25398514
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Roles of individual human cytochrome P-450 enzymes in the bioactivation of benzo(a)pyrene, 7,8-dihydroxy-7,8-dihydrobenzo(a)pyrene, and other dihydrodiol derivatives of polycyclic aromatic hydrocarbons.
    Shimada T; Martin MV; Pruess-Schwartz D; Marnett LJ; Guengerich FP
    Cancer Res; 1989 Nov; 49(22):6304-12. PubMed ID: 2509067
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Urban dust particulate matter alters PAH-induced carcinogenesis by inhibition of CYP1A1 and CYP1B1.
    Courter LA; Musafia-Jeknic T; Fischer K; Bildfell R; Giovanini J; Pereira C; Baird WM
    Toxicol Sci; 2007 Jan; 95(1):63-73. PubMed ID: 17060372
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Role of c-Jun-N-Terminal Kinase in Pregnane X Receptor-Mediated Induction of Human Cytochrome P4503A4 In Vitro.
    Taneja G; Chu C; Maturu P; Moorthy B; Ghose R
    Drug Metab Dispos; 2018 Apr; 46(4):397-404. PubMed ID: 29440179
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Simultaneous assessment of cytochrome P450 activity in cultured human hepatocytes for compound-mediated induction of CYP3A4, CYP2B6, and CYP1A2.
    Rhodes SP; Otten JN; Hingorani GP; Hartley DP; Franklin RB
    J Pharmacol Toxicol Methods; 2011; 63(3):223-6. PubMed ID: 21111054
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Activation of the aryl hydrocarbon receptor decreases rifampicin-induced CYP3A4 expression in primary human hepatocytes and HepaRG.
    Rasmussen MK; Daujat-Chavanieu M; Gerbal-Chaloin S
    Toxicol Lett; 2017 Aug; 277():1-8. PubMed ID: 28571685
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Glutathione depletion suppresses conjugation of benzo[a]pyrene metabolites and (+/-)-trans-7,8-dihydroxy-7,8-dihydrobenzo[a]pyrene metabolites with glutathione but does not affect their binding to DNA in C3H/10T1/2 mouse fibroblasts.
    Hesse S; Krupski-Brennstuhl G; Cumpelik O; Mezger M; Wiebel FJ
    Carcinogenesis; 1987 Aug; 8(8):1051-8. PubMed ID: 3608089
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Glucocorticoid-mediated induction of CYP3A4 is decreased by disruption of a protein: DNA interaction distinct from the pregnane X receptor response element.
    El-Sankary W; Bombail V; Gibson GG; Plant N
    Drug Metab Dispos; 2002 Sep; 30(9):1029-34. PubMed ID: 12167569
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 56.