BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

364 related articles for article (PubMed ID: 23846654)

  • 1. Temporal regulation of EGF signalling networks by the scaffold protein Shc1.
    Zheng Y; Zhang C; Croucher DR; Soliman MA; St-Denis N; Pasculescu A; Taylor L; Tate SA; Hardy WR; Colwill K; Dai AY; Bagshaw R; Dennis JW; Gingras AC; Daly RJ; Pawson T
    Nature; 2013 Jul; 499(7457):166-71. PubMed ID: 23846654
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Signaling adaptor ShcD suppresses extracellular signal-regulated kinase (Erk) phosphorylation distal to the Ret and Trk neurotrophic receptors.
    Wills MK; Keyvani Chahi A; Lau HR; Tilak M; Guild BD; New LA; Lu P; Jacquet K; Meakin SO; Bisson N; Jones N
    J Biol Chem; 2017 Apr; 292(14):5748-5759. PubMed ID: 28213521
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Epidermal growth factor receptors containing a single tyrosine in their C-terminal tail bind different effector molecules and are signaling-competent.
    Gill K; Macdonald-Obermann JL; Pike LJ
    J Biol Chem; 2017 Dec; 292(50):20744-20755. PubMed ID: 29074618
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The adaptor proteins p66Shc and Grb2 regulate the activation of the GTPases ARF1 and ARF6 in invasive breast cancer cells.
    Haines E; Saucier C; Claing A
    J Biol Chem; 2014 Feb; 289(9):5687-703. PubMed ID: 24407288
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Tyrosine phosphorylation of Cbl upon epidermal growth factor (EGF) stimulation and its association with EGF receptor and downstream signaling proteins.
    Fukazawa T; Miyake S; Band V; Band H
    J Biol Chem; 1996 Jun; 271(24):14554-9. PubMed ID: 8662998
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Related adhesion focal tyrosine kinase and the epidermal growth factor receptor mediate the stimulation of mitogen-activated protein kinase by the G-protein-coupled P2Y2 receptor. Phorbol ester or [Ca2+]i elevation can substitute for receptor activation.
    Soltoff SP
    J Biol Chem; 1998 Sep; 273(36):23110-7. PubMed ID: 9722539
    [TBL] [Abstract][Full Text] [Related]  

  • 7. EGF-receptor specificity for phosphotyrosine-primed substrates provides signal integration with Src.
    Begley MJ; Yun CH; Gewinner CA; Asara JM; Johnson JL; Coyle AJ; Eck MJ; Apostolou I; Cantley LC
    Nat Struct Mol Biol; 2015 Dec; 22(12):983-90. PubMed ID: 26551075
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The involvement of the docking protein Gab1 in mitogenic signalling induced by EGF and HGF in rat hepatocytes.
    Aasrum M; Ødegård J; Sandnes D; Christoffersen T
    Biochim Biophys Acta; 2013 Dec; 1833(12):3286-3294. PubMed ID: 24126105
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Functional importance of amino-terminal domain of Shc for interaction with insulin and epidermal growth factor receptors in phosphorylation-independent manner.
    Sasaoka T; Ishihara H; Sawa T; Ishiki M; Morioka H; Imamura T; Usui I; Takata Y; Kobayashi M
    J Biol Chem; 1996 Aug; 271(33):20082-7. PubMed ID: 8702728
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Cholecystokinin stimulates extracellular signal-regulated kinase through activation of the epidermal growth factor receptor, Yes, and protein kinase C. Signal amplification at the level of Raf by activation of protein kinase Cepsilon.
    Piiper A; Elez R; You SJ; Kronenberger B; Loitsch S; Roche S; Zeuzem S
    J Biol Chem; 2003 Feb; 278(9):7065-72. PubMed ID: 12496267
    [TBL] [Abstract][Full Text] [Related]  

  • 11. A conserved amino-terminal Shc domain binds to phosphotyrosine motifs in activated receptors and phosphopeptides.
    van der Geer P; Wiley S; Lai VK; Olivier JP; Gish GD; Stephens R; Kaplan D; Shoelson S; Pawson T
    Curr Biol; 1995 Apr; 5(4):404-12. PubMed ID: 7542991
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The Shc adaptor protein is highly phosphorylated at conserved, twin tyrosine residues (Y239/240) that mediate protein-protein interactions.
    van der Geer P; Wiley S; Gish GD; Pawson T
    Curr Biol; 1996 Nov; 6(11):1435-44. PubMed ID: 8939605
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Differential utilization of ShcA tyrosine residues and functional domains in the transduction of epidermal growth factor-induced mitogen-activated protein kinase activation in 293T cells and nerve growth factor-induced neurite outgrowth in PC12 cells. Identification of a new Grb2.Sos1 binding site.
    Thomas D; Bradshaw RA
    J Biol Chem; 1997 Aug; 272(35):22293-9. PubMed ID: 9268379
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Signaling complexes and protein-protein interactions involved in the activation of the Ras and phosphatidylinositol 3-kinase pathways by the c-Ret receptor tyrosine kinase.
    Besset V; Scott RP; Ibáñez CF
    J Biol Chem; 2000 Dec; 275(50):39159-66. PubMed ID: 10995764
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Analytical reduction of combinatorial complexity arising from multiple protein modification sites.
    Birtwistle MR
    J R Soc Interface; 2015 Feb; 12(103):. PubMed ID: 25519995
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Involvement of ErbB2 in the signaling pathway leading to cell cycle progression from a truncated epidermal growth factor receptor lacking the C-terminal autophosphorylation sites.
    Sasaoka T; Langlois WJ; Bai F; Rose DW; Leitner JW; Decker SJ; Saltiel A; Gill GN; Kobayashi M; Draznin B; Olefsky JM
    J Biol Chem; 1996 Apr; 271(14):8338-44. PubMed ID: 8626530
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Adaptor protein Shc undergoes translocation and mediates up-regulation of the tyrosine kinase c-Src in EGF-stimulated A431 cells.
    Sato K; Kimoto M; Kakumoto M; Horiuchi D; Iwasaki T; Tokmakov AA; Fukami Y
    Genes Cells; 2000 Sep; 5(9):749-64. PubMed ID: 10971656
    [TBL] [Abstract][Full Text] [Related]  

  • 18. p66shc inhibits pro-survival epidermal growth factor receptor/ERK signaling during severe oxidative stress in mouse renal proximal tubule cells.
    Arany I; Faisal A; Nagamine Y; Safirstein RL
    J Biol Chem; 2008 Mar; 283(10):6110-7. PubMed ID: 18174162
    [TBL] [Abstract][Full Text] [Related]  

  • 19. GAREM, a novel adaptor protein for growth factor receptor-bound protein 2, contributes to cellular transformation through the activation of extracellular signal-regulated kinase signaling.
    Tashiro K; Tsunematsu T; Okubo H; Ohta T; Sano E; Yamauchi E; Taniguchi H; Konishi H
    J Biol Chem; 2009 Jul; 284(30):20206-14. PubMed ID: 19509291
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The ShcD signaling adaptor facilitates ligand-independent phosphorylation of the EGF receptor.
    Wills MK; Tong J; Tremblay SL; Moran MF; Jones N
    Mol Biol Cell; 2014 Mar; 25(6):739-52. PubMed ID: 24430869
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 19.