BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

539 related articles for article (PubMed ID: 23851116)

  • 61. Synthesis and biological evaluation of novel pyrimidine-benzimidazol hybrids as potential anticancer agents.
    Shao KP; Zhang XY; Chen PJ; Xue DQ; He P; Ma LY; Zheng JX; Zhang QR; Liu HM
    Bioorg Med Chem Lett; 2014 Aug; 24(16):3877-81. PubMed ID: 25001482
    [TBL] [Abstract][Full Text] [Related]  

  • 62. Synthesis and antitumor properties of pyrazolo [3,4-D] pyrimidine derivatives.
    Witkiewicz K; Machoń Z; Mordarski M; Wieczorek J
    Pol J Pharmacol Pharm; 1987; 39(6):715-20. PubMed ID: 3503990
    [TBL] [Abstract][Full Text] [Related]  

  • 63. Microwave-assisted synthesis, crystal structure of pyrazolo[1,5-a]pyrazin-4(5H)-ones and their selective effects on lung cancer cells.
    Liu N; Zhang JH; Zhao BX; Zhao J; Su L; Dong WL; Zhang SL; Miao JY
    Eur J Med Chem; 2011 Jun; 46(6):2359-67. PubMed ID: 21463913
    [TBL] [Abstract][Full Text] [Related]  

  • 64. Synthesis and biological evaluation of 1-aryl-4,5-dihydro-1H-pyrazolo[3,4-d]pyrimidin-4-one inhibitors of cyclin-dependent kinases.
    Markwalder JA; Arnone MR; Benfield PA; Boisclair M; Burton CR; Chang CH; Cox SS; Czerniak PM; Dean CL; Doleniak D; Grafstrom R; Harrison BA; Kaltenbach RF; Nugiel DA; Rossi KA; Sherk SR; Sisk LM; Stouten P; Trainor GL; Worland P; Seitz SP
    J Med Chem; 2004 Nov; 47(24):5894-911. PubMed ID: 15537345
    [TBL] [Abstract][Full Text] [Related]  

  • 65. Synthesis and antiproliferative activity of imidazo[1,2-a]pyrimidine Mannich bases.
    Aeluri R; Alla M; Polepalli S; Jain N
    Eur J Med Chem; 2015 Jul; 100():18-23. PubMed ID: 26067381
    [TBL] [Abstract][Full Text] [Related]  

  • 66. Synthesis of new pyrazolo[3,4-d]pyrimidine derivatives and evaluation of their anti-inflammatory and anticancer activities.
    Abd El Razik HA; Mroueh M; Faour WH; Shebaby WN; Daher CF; Ashour HMA; Ragab HM
    Chem Biol Drug Des; 2017 Jul; 90(1):83-96. PubMed ID: 28032452
    [TBL] [Abstract][Full Text] [Related]  

  • 67. Synthesis and mechanistic aspects of 2-anilinonicotinyl-pyrazolo[1,5-a]pyrimidine conjugates that regulate cell proliferation in MCF-7 cells via estrogen signaling.
    Kamal A; Faazil S; Hussaini SM; Ramaiah MJ; Balakrishna M; Patel N; Pushpavalli SN; Pal-Bhadra M
    Bioorg Med Chem Lett; 2016 Apr; 26(8):2077-83. PubMed ID: 26948540
    [TBL] [Abstract][Full Text] [Related]  

  • 68. Novel 6-N-arylcarboxamidopyrazolo[4,3-d]pyrimidin-7-one derivatives as potential anti-cancer agents.
    Devegowda VN; Kim JH; Han KC; Yang EG; Choo H; Pae AN; Nam G; Choi KI
    Bioorg Med Chem Lett; 2010 Mar; 20(5):1630-3. PubMed ID: 20138760
    [TBL] [Abstract][Full Text] [Related]  

  • 69. Design and synthesis of pyrazolo[3,4-d]pyrimidines: Nitric oxide releasing compounds targeting hepatocellular carcinoma.
    Elshaier YAMM; Shaaban MA; Abd El Hamid MK; Abdelrahman MH; Abou-Salim MA; Elgazwi SM; Halaweish F
    Bioorg Med Chem; 2017 Jun; 25(12):2956-2970. PubMed ID: 28487127
    [TBL] [Abstract][Full Text] [Related]  

  • 70. Synthesis, Cytotoxicity, Antimicrobial and Docking Simulation of Novel Pyrazolo[3,4-d]pyrimidine and pyrazolo[4,3-e][1,2,4]triazolo[3,4-c] pyrimidine Derivatives.
    Hassaneen HM; Saleh FM; Abdallah TA; Mohamed MF; Mohamed YS; Awad EM; Abdelhamid IA
    Mini Rev Med Chem; 2019; 19(8):657-670. PubMed ID: 30332953
    [TBL] [Abstract][Full Text] [Related]  

  • 71. Design and synthesis of novel 3-sulfonylpyrazol-4-amino pyrimidines as potent anaplastic lymphoma kinase (ALK) inhibitors.
    Zhang P; Dong J; Zhong B; Zhang D; Yuan H; Jin C; Xu X; Li H; Zhou Y; Liang Z; Ji M; Xu T; Song G; Zhang L; Chen G; Meng X; Sun D; Shih J; Zhang R; Hou G; Wang C; Jin Y; Yang Q
    Bioorg Med Chem Lett; 2016 Apr; 26(8):1910-8. PubMed ID: 26979157
    [TBL] [Abstract][Full Text] [Related]  

  • 72. Synthesis, anticancer activity and effects on cell cycle profile and apoptosis of novel thieno[2,3-d]pyrimidine and thieno[3,2-e] triazolo[4,3-c]pyrimidine derivatives.
    Kandeel MM; Refaat HM; Kassab AE; Shahin IG; Abdelghany TM
    Eur J Med Chem; 2015 Jan; 90():620-32. PubMed ID: 25499930
    [TBL] [Abstract][Full Text] [Related]  

  • 73. An appraisal on synthetic and pharmaceutical perspectives of pyrazolo[4,3-d]pyrimidine scaffold.
    Cherukupalli S; Hampannavar GA; Chinnam S; Chandrasekaran B; Sayyad N; Kayamba F; Reddy Aleti R; Karpoormath R
    Bioorg Med Chem; 2018 Jan; 26(2):309-339. PubMed ID: 29273417
    [TBL] [Abstract][Full Text] [Related]  

  • 74. 2,4-diamino-5-deaza-6-substituted pyrido[2,3-d]pyrimidine antifolates as potent and selective nonclassical inhibitors of dihydrofolate reductases.
    Gangjee A; Vasudevan A; Queener SF; Kisliuk RL
    J Med Chem; 1996 Mar; 39(7):1438-46. PubMed ID: 8691474
    [TBL] [Abstract][Full Text] [Related]  

  • 75. The unsaturated acyclic nucleoside analogues bearing a sterically constrained (Z)-4'-benzamido-2'-butenyl moiety: Synthesis, X-ray crystal structure study, cytostatic and antiviral activity evaluations.
    Benci K; Wittine K; Radan M; Cetina M; Sedić M; Kraljević Pavelić S; Pavelić K; Clercq ED; Mintas M
    Bioorg Med Chem; 2010 Sep; 18(17):6249-57. PubMed ID: 20696582
    [TBL] [Abstract][Full Text] [Related]  

  • 76. Synthesis and kinase inhibitory activity of new sulfonamide derivatives of pyrazolo[4,3-e][1,2,4]triazines.
    Mojzych M; Šubertová V; Bielawska A; Bielawski K; Bazgier V; Berka K; Gucký T; Fornal E; Kryštof V
    Eur J Med Chem; 2014 May; 78():217-24. PubMed ID: 24681986
    [TBL] [Abstract][Full Text] [Related]  

  • 77. An unexpected Dimroth rearrangement leading to annelated thieno[3,2-d][1,2,3]triazolo[1,5-a]pyrimidines with potent antitumor activity.
    Lauria A; Patella C; Abbate I; Martorana A; Almerico AM
    Eur J Med Chem; 2013 Jul; 65():381-8. PubMed ID: 23747807
    [TBL] [Abstract][Full Text] [Related]  

  • 78. Synthesis, antimicrobial and anti-cancer activities of some new N-ethyl, N-benzyl and N-benzoyl-3-indolyl heterocycles.
    El-Sawy ER; Mandour AH; Mahmoud K; Islam IE; Abo-Salem HM
    Acta Pharm; 2012 Jun; 62(2):157-79. PubMed ID: 22750815
    [TBL] [Abstract][Full Text] [Related]  

  • 79. Identification of a novel pyrazolo[3,4-d]pyrimidine able to inhibit cell proliferation of a human osteogenic sarcoma in vitro and in a xenograft model in mice.
    Manetti F; Santucci A; Locatelli GA; Maga G; Spreafico A; Serchi T; Orlandini M; Bernardini G; Caradonna NP; Spallarossa A; Brullo C; Schenone S; Bruno O; Ranise A; Bondavalli F; Hoffmann O; Bologna M; Angelucci A; Botta M
    J Med Chem; 2007 Nov; 50(23):5579-88. PubMed ID: 17929792
    [TBL] [Abstract][Full Text] [Related]  

  • 80. Antiproliferative activity of new 1-aryl-4-amino-1H-pyrazolo[3,4-d]pyrimidine derivatives toward the human epidermoid carcinoma A431 cell line.
    Schenone S; Bruno O; Bondavalli F; Ranise A; Mosti L; Menozzi G; Fossa P; Donnini S; Santoro A; Ziche M; Manetti F; Botta M
    Eur J Med Chem; 2004 Nov; 39(11):939-46. PubMed ID: 15501543
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 27.