191 related articles for article (PubMed ID: 23851339)
1. A sensitive fluorigenic substrate for selective in vitro and in vivo assay of leukotriene A4 hydrolase activity.
Poras H; Duquesnoy S; Fournié-Zaluski MC; Ratinaud-Giraud C; Roques BP; Ouimet T
Anal Biochem; 2013 Oct; 441(2):152-61. PubMed ID: 23851339
[TBL] [Abstract][Full Text] [Related]
2. Dual anti-inflammatory and selective inhibition mechanism of leukotriene A4 hydrolase/aminopeptidase: insights from comparative molecular dynamics and binding free energy analyses.
Appiah-Kubi P; Soliman ME
J Biomol Struct Dyn; 2016 Nov; 34(11):2418-33. PubMed ID: 26555301
[TBL] [Abstract][Full Text] [Related]
3. Capturing LTA
Stsiapanava A; Samuelsson B; Haeggström JZ
Proc Natl Acad Sci U S A; 2017 Sep; 114(36):9689-9694. PubMed ID: 28827365
[TBL] [Abstract][Full Text] [Related]
4. Feasibility and physiological relevance of designing highly potent aminopeptidase-sparing leukotriene A4 hydrolase inhibitors.
Numao S; Hasler F; Laguerre C; Srinivas H; Wack N; Jäger P; Schmid A; Osmont A; Röthlisberger P; Houguenade J; Bergsdorf C; Dawson J; Carte N; Hofmann A; Markert C; Hardaker L; Billich A; Wolf RM; Penno CA; Bollbuck B; Miltz W; Röhn TA
Sci Rep; 2017 Oct; 7(1):13591. PubMed ID: 29051536
[TBL] [Abstract][Full Text] [Related]
5. Binding of Pro-Gly-Pro at the active site of leukotriene A4 hydrolase/aminopeptidase and development of an epoxide hydrolase selective inhibitor.
Stsiapanava A; Olsson U; Wan M; Kleinschmidt T; Rutishauser D; Zubarev RA; Samuelsson B; Rinaldo-Matthis A; Haeggström JZ
Proc Natl Acad Sci U S A; 2014 Mar; 111(11):4227-32. PubMed ID: 24591641
[TBL] [Abstract][Full Text] [Related]
6. Hybrid Receptor-Bound/MM-GBSA-Per-residue Energy-Based Pharmacophore Modelling: Enhanced Approach for Identification of Selective LTA4H Inhibitors as Potential Anti-inflammatory Drugs.
Appiah-Kubi P; Soliman M
Cell Biochem Biophys; 2017 Mar; 75(1):35-48. PubMed ID: 27914004
[TBL] [Abstract][Full Text] [Related]
7. Synthesis, docking, cytotoxicity, and LTA
El-Naggar MH; Mira A; Abdel Bar FM; Shimizu K; Amer MM; Badria FA
Bioorg Med Chem; 2017 Feb; 25(3):1277-1285. PubMed ID: 28065501
[TBL] [Abstract][Full Text] [Related]
8. The development of novel LTA
Low CM; Akthar S; Patel DF; Löser S; Wong CT; Jackson PL; Blalock JE; Hare SA; Lloyd CM; Snelgrove RJ
Sci Rep; 2017 Mar; 7():44449. PubMed ID: 28303931
[TBL] [Abstract][Full Text] [Related]
9. A remarkable activity of human leukotriene A4 hydrolase (LTA4H) toward unnatural amino acids.
Byzia A; Haeggström JZ; Salvesen GS; Drag M
Amino Acids; 2014 May; 46(5):1313-20. PubMed ID: 24573245
[TBL] [Abstract][Full Text] [Related]
10. Leukotriene A4 hydrolase as a target for cancer prevention and therapy.
Chen X; Wang S; Wu N; Yang CS
Curr Cancer Drug Targets; 2004 May; 4(3):267-83. PubMed ID: 15134534
[TBL] [Abstract][Full Text] [Related]
11. Identification of Human Leukotriene A4 Hydrolase Inhibitors Using Structure-Based Pharmacophore Modeling and Molecular Docking.
Audat SA; Al-Shar'i NA; Al-Oudat BA; Bryant-Friedrich A; Bedi MF; Zayed AL; Al-Balas QA
Molecules; 2020 Jun; 25(12):. PubMed ID: 32580506
[TBL] [Abstract][Full Text] [Related]
12. In silico modeling of the molecular structure and binding of leukotriene A4 into leukotriene A4 hydrolase.
Paz PB; Vega-Hissi EG; Estrada MR; Garro Martinez JC
Chem Biol Drug Des; 2012 Dec; 80(6):902-8. PubMed ID: 22913921
[TBL] [Abstract][Full Text] [Related]
13. Development of a homogeneous time-resolved fluorescence leukotriene B4 assay for determining the activity of leukotriene A4 hydrolase.
Liang AM; Claret E; Ouled-Diaf J; Jean A; Vogel D; Light DR; Jones SW; Guilford WJ; Parkinson JF; Snider RM
J Biomol Screen; 2007 Jun; 12(4):536-45. PubMed ID: 17384330
[TBL] [Abstract][Full Text] [Related]
14. Leukotriene A4 hydrolase, insights into the molecular evolution by homology modeling and mutational analysis of enzyme from Saccharomyces cerevisiae.
Tholander F; Kull F; Ohlson E; Shafqat J; Thunnissen MM; Haeggström JZ
J Biol Chem; 2005 Sep; 280(39):33477-86. PubMed ID: 16024909
[TBL] [Abstract][Full Text] [Related]
15. Thermodynamic properties of leukotriene A
Wittmann SK; Kalinowsky L; Kramer JS; Bloecher R; Knapp S; Steinhilber D; Pogoryelov D; Proschak E; Heering J
Bioorg Med Chem; 2016 Nov; 24(21):5243-5248. PubMed ID: 27651294
[TBL] [Abstract][Full Text] [Related]
16. Leukotriene A4 hydrolase: identification of a common carboxylate recognition site for the epoxide hydrolase and aminopeptidase substrates.
Rudberg PC; Tholander F; Andberg M; Thunnissen MM; Haeggström JZ
J Biol Chem; 2004 Jun; 279(26):27376-82. PubMed ID: 15078870
[TBL] [Abstract][Full Text] [Related]
17. Modification of leukotriene A(4) hydrolase/aminopeptidase by sulfhydryl-blocking reagents: differential effects on dual enzyme activities by methyl-methane thiosulfonate.
Orning L; Fitzpatrick FA
Arch Biochem Biophys; 1999 Aug; 368(1):131-8. PubMed ID: 10415120
[TBL] [Abstract][Full Text] [Related]
18. Product formation controlled by substrate dynamics in leukotriene A4 hydrolase.
Stsiapanava A; Tholander F; Kumar RB; Qureshi AA; Niegowski D; Hasan M; Thunnissen M; Haeggström JZ; Rinaldo-Matthis A
Biochim Biophys Acta; 2014 Feb; 1844(2):439-46. PubMed ID: 24333438
[TBL] [Abstract][Full Text] [Related]
19. Aminopeptidase B is structurally related to leukotriene-A4 hydrolase but is not a bifunctional enzyme with epoxide hydrolase activity.
Fukasawa KM; Fukasawa K; Harada M; Hirose J; Izumi T; Shimizu T
Biochem J; 1999 May; 339 ( Pt 3)(Pt 3):497-502. PubMed ID: 10215585
[TBL] [Abstract][Full Text] [Related]
20. Leukotriene A4 hydrolase: mapping of a henicosapeptide involved in mechanism-based inactivation.
Mueller MJ; Wetterholm A; Blomster M; Jörnvall H; Samuelsson B; Haeggström JZ
Proc Natl Acad Sci U S A; 1995 Aug; 92(18):8383-7. PubMed ID: 7667299
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
