These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

186 related articles for article (PubMed ID: 23853097)

  • 1. Structural insights into the neutralization mechanism of monoclonal antibody 6C2 against ricin.
    Zhu Y; Dai J; Zhang T; Li X; Fang P; Wang H; Jiang Y; Yu X; Xia T; Niu L; Guo Y; Teng M
    J Biol Chem; 2013 Aug; 288(35):25165-25172. PubMed ID: 23853097
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Crystal structures of ricin toxin's enzymatic subunit (RTA) in complex with neutralizing and non-neutralizing single-chain antibodies.
    Rudolph MJ; Vance DJ; Cheung J; Franklin MC; Burshteyn F; Cassidy MS; Gary EN; Herrera C; Shoemaker CB; Mantis NJ
    J Mol Biol; 2014 Aug; 426(17):3057-68. PubMed ID: 24907552
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Arginine residues on the opposite side of the active site stimulate the catalysis of ribosome depurination by ricin A chain by interacting with the P-protein stalk.
    Li XP; Kahn PC; Kahn JN; Grela P; Tumer NE
    J Biol Chem; 2013 Oct; 288(42):30270-30284. PubMed ID: 24003229
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Structural analysis of nested neutralizing and non-neutralizing B cell epitopes on ricin toxin's enzymatic subunit.
    Rudolph MJ; Vance DJ; Cassidy MS; Rong Y; Shoemaker CB; Mantis NJ
    Proteins; 2016 Aug; 84(8):1162-72. PubMed ID: 27159829
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Single-domain antibodies neutralize ricin toxin intracellularly by blocking access to ribosomal P-stalk proteins.
    Czajka TF; Vance DJ; Davis S; Rudolph MJ; Mantis NJ
    J Biol Chem; 2022 Apr; 298(4):101742. PubMed ID: 35182523
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Stability of isolated antibody-antigen complexes as a predictive tool for selecting toxin neutralizing antibodies.
    Legler PM; Compton JR; Hale ML; Anderson GP; Olson MA; Millard CB; Goldman ER
    MAbs; 2017 Jan; 9(1):43-57. PubMed ID: 27660893
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Leucine 232 and hydrophobic residues at the ribosomal P stalk binding site are critical for biological activity of ricin.
    Zhou Y; Li XP; Kahn JN; McLaughlin JE; Tumer NE
    Biosci Rep; 2019 Oct; 39(10):. PubMed ID: 31548364
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The ribosomal stalk is required for ribosome binding, depurination of the rRNA and cytotoxicity of ricin A chain in Saccharomyces cerevisiae.
    Chiou JC; Li XP; Remacha M; Ballesta JP; Tumer NE
    Mol Microbiol; 2008 Dec; 70(6):1441-52. PubMed ID: 19019145
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Structural insights into the interaction of the ribosomal P stalk protein P2 with a type II ribosome-inactivating protein ricin.
    Fan X; Zhu Y; Wang C; Niu L; Teng M; Li X
    Sci Rep; 2016 Nov; 6():37803. PubMed ID: 27886256
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Structural basis for neutralization of cytotoxic abrin by monoclonal antibody D6F10.
    Bansia H; Bagaria S; Karande AA; Ramakumar S
    FEBS J; 2019 Mar; 286(5):1003-1029. PubMed ID: 30521151
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Pentameric organization of the ribosomal stalk accelerates recruitment of ricin a chain to the ribosome for depurination.
    Li XP; Grela P; Krokowski D; Tchórzewski M; Tumer NE
    J Biol Chem; 2010 Dec; 285(53):41463-71. PubMed ID: 20974854
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Structural Analysis of Single Domain Antibodies Bound to a Second Neutralizing Hot Spot on Ricin Toxin's Enzymatic Subunit.
    Rudolph MJ; Vance DJ; Cassidy MS; Rong Y; Mantis NJ
    J Biol Chem; 2017 Jan; 292(3):872-883. PubMed ID: 27903650
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Identification of a novel functional domain of ricin responsible for its potent toxicity.
    Dai J; Zhao L; Yang H; Guo H; Fan K; Wang H; Qian W; Zhang D; Li B; Wang H; Guo Y
    J Biol Chem; 2011 Apr; 286(14):12166-71. PubMed ID: 21303906
    [TBL] [Abstract][Full Text] [Related]  

  • 14. A two-step binding model proposed for the electrostatic interactions of ricin a chain with ribosomes.
    Li XP; Chiou JC; Remacha M; Ballesta JP; Tumer NE
    Biochemistry; 2009 May; 48(18):3853-63. PubMed ID: 19292477
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Intracellular Neutralization of Ricin Toxin by Single-domain Antibodies Targeting the Active Site.
    Rudolph MJ; Czajka TF; Davis SA; Thi Nguyen CM; Li XP; Tumer NE; Vance DJ; Mantis NJ
    J Mol Biol; 2020 Feb; 432(4):1109-1125. PubMed ID: 31931008
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Crystal Structure of Ribosome-Inactivating Protein Ricin A Chain in Complex with the C-Terminal Peptide of the Ribosomal Stalk Protein P2.
    Shi WW; Tang YS; Sze SY; Zhu ZN; Wong KB; Shaw PC
    Toxins (Basel); 2016 Oct; 8(10):. PubMed ID: 27754366
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Neutralizing monoclonal antibodies against ricin's enzymatic subunit interfere with protein disulfide isomerase-mediated reduction of ricin holotoxin in vitro.
    O'Hara JM; Mantis NJ
    J Immunol Methods; 2013 Sep; 395(1-2):71-8. PubMed ID: 23774033
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The P1/P2 proteins of the human ribosomal stalk are required for ribosome binding and depurination by ricin in human cells.
    May KL; Li XP; Martínez-Azorín F; Ballesta JP; Grela P; Tchórzewski M; Tumer NE
    FEBS J; 2012 Oct; 279(20):3925-36. PubMed ID: 22909382
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Ribosome depurination by ricin leads to inhibition of endoplasmic reticulum stress-induced
    Pierce M; Vengsarkar D; McLaughlin JE; Kahn JN; Tumer NE
    J Biol Chem; 2019 Nov; 294(47):17848-17862. PubMed ID: 31624149
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Peptide Mimics of the Ribosomal P Stalk Inhibit the Activity of Ricin A Chain by Preventing Ribosome Binding.
    Li XP; Kahn JN; Tumer NE
    Toxins (Basel); 2018 Sep; 10(9):. PubMed ID: 30217009
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.