160 related articles for article (PubMed ID: 23859074)
21. 4-Benzylideneisoquinoline-1,3(
Senaweera S; He T; Cui H; Aihara H; Wang Z
Med Chem Res; 2021 Feb; 30(2):371-386. PubMed ID: 33776385
[TBL] [Abstract][Full Text] [Related]
22. Multiple Topoisomerase I (TopoI), Topoisomerase II (TopoII) and Tyrosyl-DNA Phosphodiesterase (TDP) inhibitors in the development of anticancer drugs.
Baglini E; Salerno S; Barresi E; Robello M; Da Settimo F; Taliani S; Marini AM
Eur J Pharm Sci; 2021 Jan; 156():105594. PubMed ID: 33059042
[TBL] [Abstract][Full Text] [Related]
23. Repair of trapped topoisomerase II covalent cleavage complexes: Novel proteasome-independent mechanisms.
Tsuda M; Kitamasu K; Hosokawa S; Nakano T; Ide H
Nucleosides Nucleotides Nucleic Acids; 2020; 39(1-3):170-184. PubMed ID: 31608820
[TBL] [Abstract][Full Text] [Related]
24. ERK3 regulates TDP2-mediated DNA damage response and chemoresistance in lung cancer cells.
Bian K; Muppani NR; Elkhadragy L; Wang W; Zhang C; Chen T; Jung S; Seternes OM; Long W
Oncotarget; 2016 Feb; 7(6):6665-75. PubMed ID: 26701725
[TBL] [Abstract][Full Text] [Related]
25. Biochemical characterization of human tyrosyl-DNA phosphodiesterase 2 (TDP2/TTRAP): a Mg(2+)/Mn(2+)-dependent phosphodiesterase specific for the repair of topoisomerase cleavage complexes.
Gao R; Huang SY; Marchand C; Pommier Y
J Biol Chem; 2012 Aug; 287(36):30842-52. PubMed ID: 22822062
[TBL] [Abstract][Full Text] [Related]
26. Novel TDP2-ubiquitin interactions and their importance for the repair of topoisomerase II-mediated DNA damage.
Rao T; Gao R; Takada S; Al Abo M; Chen X; Walters KJ; Pommier Y; Aihara H
Nucleic Acids Res; 2016 Dec; 44(21):10201-10215. PubMed ID: 27543075
[TBL] [Abstract][Full Text] [Related]
27. Effect of TDP2 on the Level of TOP2-DNA Complexes and SUMOylated TOP2-DNA Complexes.
Lee KC; Swan RL; Sondka Z; Padget K; Cowell IG; Austin CA
Int J Mol Sci; 2018 Jul; 19(7):. PubMed ID: 30011940
[TBL] [Abstract][Full Text] [Related]
28. [Tyrosyl-DNA phosphodiesterases: potential targets for cancer treatment].
Hu Z; Wang HW; An LK
Yao Xue Xue Bao; 2016 Feb; 51(2):215-25. PubMed ID: 29856574
[TBL] [Abstract][Full Text] [Related]
29. Synthesis and Biological Evaluation of the First Triple Inhibitors of Human Topoisomerase 1, Tyrosyl-DNA Phosphodiesterase 1 (Tdp1), and Tyrosyl-DNA Phosphodiesterase 2 (Tdp2).
Wang P; Elsayed MSA; Plescia CB; Ravji A; Redon CE; Kiselev E; Marchand C; Zeleznik O; Agama K; Pommier Y; Cushman M
J Med Chem; 2017 Apr; 60(8):3275-3288. PubMed ID: 28418653
[TBL] [Abstract][Full Text] [Related]
30. Triazolopyrimidine and triazolopyridine scaffolds as TDP2 inhibitors.
Ribeiro CJA; Kankanala J; Xie J; Williams J; Aihara H; Wang Z
Bioorg Med Chem Lett; 2019 Jan; 29(2):257-261. PubMed ID: 30522956
[TBL] [Abstract][Full Text] [Related]
31. Proteolytic degradation of topoisomerase II (Top2) enables the processing of Top2·DNA and Top2·RNA covalent complexes by tyrosyl-DNA-phosphodiesterase 2 (TDP2).
Gao R; Schellenberg MJ; Huang SY; Abdelmalak M; Marchand C; Nitiss KC; Nitiss JL; Williams RS; Pommier Y
J Biol Chem; 2014 Jun; 289(26):17960-9. PubMed ID: 24808172
[TBL] [Abstract][Full Text] [Related]
32. An internal ribosome entry site in the coding region of tyrosyl-DNA phosphodiesterase 2 drives alternative translation start.
Chou AC; Aslanian A; Sun H; Hunter T
J Biol Chem; 2019 Feb; 294(8):2665-2677. PubMed ID: 30593505
[TBL] [Abstract][Full Text] [Related]
33. A human 5'-tyrosyl DNA phosphodiesterase that repairs topoisomerase-mediated DNA damage.
Cortes Ledesma F; El Khamisy SF; Zuma MC; Osborn K; Caldecott KW
Nature; 2009 Oct; 461(7264):674-8. PubMed ID: 19794497
[TBL] [Abstract][Full Text] [Related]
34. The Topoisomerase I Inhibitor Irinotecan and the Tyrosyl-DNA Phosphodiesterase 1 Inhibitor Furamidine Synergistically Suppress Murine Lupus Nephritis.
Keil A; Frese-Schaper M; Steiner SK; Körner M; Schmid RA; Frese S
Arthritis Rheumatol; 2015 Jul; 67(7):1858-67. PubMed ID: 25779651
[TBL] [Abstract][Full Text] [Related]
35. Novel ciprofloxacin hybrids using biology oriented drug synthesis (BIODS) approach: Anticancer activity, effects on cell cycle profile, caspase-3 mediated apoptosis, topoisomerase II inhibition, and antibacterial activity.
Kassab AE; Gedawy EM
Eur J Med Chem; 2018 Apr; 150():403-418. PubMed ID: 29547830
[TBL] [Abstract][Full Text] [Related]
36. Tirapazamine: a hypoxia-activated topoisomerase II poison.
Peters KB; Brown JM
Cancer Res; 2002 Sep; 62(18):5248-53. PubMed ID: 12234992
[TBL] [Abstract][Full Text] [Related]
37. Synthesis and evaluation of (18)F-labeled ATP competitive inhibitors of topoisomerase II as probes for imaging topoisomerase II expression.
Daumar P; Zeglis BM; Ramos N; Divilov V; Sevak KK; Pillarsetty N; Lewis JS
Eur J Med Chem; 2014 Oct; 86():769-81. PubMed ID: 25240701
[TBL] [Abstract][Full Text] [Related]
38. TDP2-dependent non-homologous end-joining protects against topoisomerase II-induced DNA breaks and genome instability in cells and in vivo.
Gómez-Herreros F; Romero-Granados R; Zeng Z; Alvarez-Quilón A; Quintero C; Ju L; Umans L; Vermeire L; Huylebroeck D; Caldecott KW; Cortés-Ledesma F
PLoS Genet; 2013; 9(3):e1003226. PubMed ID: 23505375
[TBL] [Abstract][Full Text] [Related]
39. Recent advances in the development of dual topoisomerase I and II inhibitors as anticancer drugs.
Salerno S; Da Settimo F; Taliani S; Simorini F; La Motta C; Fornaciari G; Marini AM
Curr Med Chem; 2010; 17(35):4270-90. PubMed ID: 20939813
[TBL] [Abstract][Full Text] [Related]
40. Development of a novel assay for human tyrosyl DNA phosphodiesterase 2.
Adhikari S; Karmahapatra SK; Elias H; Dhopeshwarkar P; Williams RS; Byers S; Uren A; Roy R
Anal Biochem; 2011 Sep; 416(1):112-6. PubMed ID: 21620793
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]