312 related articles for article (PubMed ID: 23859207)
1. Small-molecule inhibition of bacterial two-component systems to combat antibiotic resistance and virulence.
Worthington RJ; Blackledge MS; Melander C
Future Med Chem; 2013 Jul; 5(11):1265-84. PubMed ID: 23859207
[TBL] [Abstract][Full Text] [Related]
2. Two-component signal transduction as potential drug targets in pathogenic bacteria.
Gotoh Y; Eguchi Y; Watanabe T; Okamoto S; Doi A; Utsumi R
Curr Opin Microbiol; 2010 Apr; 13(2):232-9. PubMed ID: 20138000
[TBL] [Abstract][Full Text] [Related]
3. Evaluation of small molecule kinase inhibitors as novel antimicrobial and antibiofilm agents.
King A; Blackledge MS
Chem Biol Drug Des; 2021 Dec; 98(6):1038-1064. PubMed ID: 34581492
[TBL] [Abstract][Full Text] [Related]
4. Paradigm shift in discovering next-generation anti-infective agents: targeting quorum sensing, c-di-GMP signaling and biofilm formation in bacteria with small molecules.
Sintim HO; Smith JA; Wang J; Nakayama S; Yan L
Future Med Chem; 2010 Jun; 2(6):1005-35. PubMed ID: 21426116
[TBL] [Abstract][Full Text] [Related]
5. Anti-virulence Strategies to Target Bacterial Infections.
Mühlen S; Dersch P
Curr Top Microbiol Immunol; 2016; 398():147-183. PubMed ID: 26942418
[TBL] [Abstract][Full Text] [Related]
6. [Two-component signal transduction as attractive drug targets in pathogenic bacteria].
Utsumi R; Igarashi M
Yakugaku Zasshi; 2012; 132(1):51-8. PubMed ID: 22214580
[TBL] [Abstract][Full Text] [Related]
7. Inhibitors targeting two-component signal transduction.
Watanabe T; Okada A; Gotoh Y; Utsumi R
Adv Exp Med Biol; 2008; 631():229-36. PubMed ID: 18792693
[TBL] [Abstract][Full Text] [Related]
8. Small molecule downregulation of PmrAB reverses lipid A modification and breaks colistin resistance.
Harris TL; Worthington RJ; Hittle LE; Zurawski DV; Ernst RK; Melander C
ACS Chem Biol; 2014 Jan; 9(1):122-7. PubMed ID: 24131198
[TBL] [Abstract][Full Text] [Related]
9. Virulence-targeted Antibacterials: Concept, Promise, and Susceptibility to Resistance Mechanisms.
Ruer S; Pinotsis N; Steadman D; Waksman G; Remaut H
Chem Biol Drug Des; 2015 Oct; 86(4):379-99. PubMed ID: 25589217
[TBL] [Abstract][Full Text] [Related]
10. Global priority pathogens: virulence, antimicrobial resistance and prospective treatment options.
M Campos JC; Antunes LC; Ferreira RB
Future Microbiol; 2020 May; 15():649-677. PubMed ID: 32495702
[No Abstract] [Full Text] [Related]
11. Bacterial histidine kinases as novel antibacterial drug targets.
Bem AE; Velikova N; Pellicer MT; Baarlen Pv; Marina A; Wells JM
ACS Chem Biol; 2015 Jan; 10(1):213-24. PubMed ID: 25436989
[TBL] [Abstract][Full Text] [Related]
12. Traffic jam at the bacterial sec translocase: targeting the SecA nanomotor by small-molecule inhibitors.
Segers K; Anné J
Chem Biol; 2011 Jun; 18(6):685-98. PubMed ID: 21700205
[TBL] [Abstract][Full Text] [Related]
13. Agents that inhibit bacterial biofilm formation.
Rabin N; Zheng Y; Opoku-Temeng C; Du Y; Bonsu E; Sintim HO
Future Med Chem; 2015; 7(5):647-71. PubMed ID: 25921403
[TBL] [Abstract][Full Text] [Related]
14. The use of quorum-sensing blockers as therapeutic agents for the control of biofilm-associated infections.
Rice SA; McDougald D; Kumar N; Kjelleberg S
Curr Opin Investig Drugs; 2005 Feb; 6(2):178-84. PubMed ID: 15751741
[TBL] [Abstract][Full Text] [Related]
15. Structure-based discovery of inhibitors of the YycG histidine kinase: new chemical leads to combat Staphylococcus epidermidis infections.
Qin Z; Zhang J; Xu B; Chen L; Wu Y; Yang X; Shen X; Molin S; Danchin A; Jiang H; Qu D
BMC Microbiol; 2006 Nov; 6():96. PubMed ID: 17094812
[TBL] [Abstract][Full Text] [Related]
16. The Small Molecule DAM Inhibitor, Pyrimidinedione, Disrupts Streptococcus pneumoniae Biofilm Growth In Vitro.
Yadav MK; Go YY; Chae SW; Song JJ
PLoS One; 2015; 10(10):e0139238. PubMed ID: 26431532
[TBL] [Abstract][Full Text] [Related]
17. Small Molecules That Sabotage Bacterial Virulence.
Johnson BK; Abramovitch RB
Trends Pharmacol Sci; 2017 Apr; 38(4):339-362. PubMed ID: 28209403
[TBL] [Abstract][Full Text] [Related]
18. Bisphosphocins: novel antimicrobials for enhanced killing of drug-resistant and biofilm-forming bacteria.
Wong JP; DiTullio P; Parkinson S
Future Microbiol; 2015; 10(11):1751-8. PubMed ID: 26597426
[TBL] [Abstract][Full Text] [Related]
19. Targeting Two-Component Systems Uncovers a Small-Molecule Inhibitor of Salmonella Virulence.
Tsai CN; MacNair CR; Cao MPT; Perry JN; Magolan J; Brown ED; Coombes BK
Cell Chem Biol; 2020 Jul; 27(7):793-805.e7. PubMed ID: 32413287
[TBL] [Abstract][Full Text] [Related]
20. [Quorum sensing of genes expression--perspective drug target against bacterial pathogenicity].
Khmel' IA; Metlitskaia AZ
Mol Biol (Mosk); 2006; 40(2):195-210. PubMed ID: 16637260
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
