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8. HACE1 negatively regulates neuroinflammation through ubiquitylating and degrading Rac1 in Parkinson's disease models. Zang CX; Wang L; Yang HY; Shang JM; Liu H; Zhang ZH; Ju C; Yuan FY; Li FY; Bao XQ; Zhang D Acta Pharmacol Sin; 2022 Feb; 43(2):285-294. PubMed ID: 34593974 [TBL] [Abstract][Full Text] [Related]
9. The HACE1 E3 ligase mediates RAC1-dependent control of mTOR signaling complexes. Turgu B; El-Naggar A; Kogler M; Tortola L; Zhang HF; Hassan M; Lizardo MM; Kung SH; Lam W; Penninger JM; Sorensen PH EMBO Rep; 2023 Dec; 24(12):e56815. PubMed ID: 37846480 [TBL] [Abstract][Full Text] [Related]
10. HACE1 blocks HIF1α accumulation under hypoxia in a RAC1 dependent manner. Turgu B; Zhang F; El-Naggar A; Negri GL; Kogler M; Tortola L; Johnson F; Ng T; Li A; Yapp D; Lockwood W; Martinez D; Maris JM; Daugaard M; Penninger JM; Hughes CS; Sorensen PH Oncogene; 2021 Mar; 40(11):1988-2001. PubMed ID: 33603169 [TBL] [Abstract][Full Text] [Related]
11. The tumour suppressor HACE1 controls cell migration by regulating Rac1 degradation. Castillo-Lluva S; Tan CT; Daugaard M; Sorensen PH; Malliri A Oncogene; 2013 Mar; 32(13):1735-42. PubMed ID: 22614015 [TBL] [Abstract][Full Text] [Related]
12. Rac1 is required for cardiomyocyte apoptosis during hyperglycemia. Shen E; Li Y; Li Y; Shan L; Zhu H; Feng Q; Arnold JM; Peng T Diabetes; 2009 Oct; 58(10):2386-95. PubMed ID: 19592621 [TBL] [Abstract][Full Text] [Related]
13. Phosphatidylinositol 3-kinase-dependent membrane recruitment of Rac-1 and p47phox is critical for alpha-platelet-derived growth factor receptor-induced production of reactive oxygen species. Bäumer AT; Ten Freyhaus H; Sauer H; Wartenberg M; Kappert K; Schnabel P; Konkol C; Hescheler J; Vantler M; Rosenkranz S J Biol Chem; 2008 Mar; 283(12):7864-76. PubMed ID: 18070887 [TBL] [Abstract][Full Text] [Related]
15. A novel Rac1 GAP splice variant relays poly-Ub accumulation signals to mediate Rac1 inactivation. Huang TY; Michael S; Xu T; Sarkeshik A; Moresco JJ; Yates JR; Masliah E; Bokoch GM; DerMardirossian C Mol Biol Cell; 2013 Feb; 24(3):194-209. PubMed ID: 23223568 [TBL] [Abstract][Full Text] [Related]
16. Oxygen sensor FIH inhibits HACE1-dependent ubiquitination of Rac1 to enhance metastatic potential in breast cancer cells. Kim I; Shin SH; Lee JE; Park JW Oncogene; 2019 May; 38(19):3651-3666. PubMed ID: 30659265 [TBL] [Abstract][Full Text] [Related]
17. Identification of cancer-associated missense mutations in hace1 that impair cell growth control and Rac1 ubiquitylation. Andrio E; Lotte R; Hamaoui D; Cherfils J; Doye A; Daugaard M; Sorensen PH; Bost F; Ruimy R; Mettouchi A; Lemichez E Sci Rep; 2017 Mar; 7():44779. PubMed ID: 28317937 [TBL] [Abstract][Full Text] [Related]
18. Role of Rac1 GTPase in NADPH oxidase activation and cognitive impairment following cerebral ischemia in the rat. Raz L; Zhang QG; Zhou CF; Han D; Gulati P; Yang LC; Yang F; Wang RM; Brann DW PLoS One; 2010 Sep; 5(9):e12606. PubMed ID: 20830300 [TBL] [Abstract][Full Text] [Related]
19. Alsin and SOD1(G93A) proteins regulate endosomal reactive oxygen species production by glial cells and proinflammatory pathways responsible for neurotoxicity. Li Q; Spencer NY; Pantazis NJ; Engelhardt JF J Biol Chem; 2011 Nov; 286(46):40151-62. PubMed ID: 21937428 [TBL] [Abstract][Full Text] [Related]
20. Rac1-NADPH oxidase signaling promotes CD36 activation under glucotoxic conditions in pancreatic beta cells. Elumalai S; Karunakaran U; Lee IK; Moon JS; Won KC Redox Biol; 2017 Apr; 11():126-134. PubMed ID: 27912197 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]