BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

146 related articles for article (PubMed ID: 23864426)

  • 1. Investigation into the feasibility of thioditaloside as a novel scaffold for galectin-3-specific inhibitors.
    Bum-Erdene K; Gagarinov IA; Collins PM; Winger M; Pearson AG; Wilson JC; Leffler H; Nilsson UJ; Grice ID; Blanchard H
    Chembiochem; 2013 Jul; 14(11):1331-42. PubMed ID: 23864426
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Taloside inhibitors of galectin-1 and galectin-3.
    Collins PM; Oberg CT; Leffler H; Nilsson UJ; Blanchard H
    Chem Biol Drug Des; 2012 Mar; 79(3):339-46. PubMed ID: 22136701
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Galectin inhibitory disaccharides promote tumour immunity in a breast cancer model.
    Stannard KA; Collins PM; Ito K; Sullivan EM; Scott SA; Gabutero E; Darren Grice I; Low P; Nilsson UJ; Leffler H; Blanchard H; Ralph SJ
    Cancer Lett; 2010 Dec; 299(2):95-110. PubMed ID: 20826047
    [TBL] [Abstract][Full Text] [Related]  

  • 4. 1H-1,2,3-triazol-1-yl thiodigalactoside derivatives as high affinity galectin-3 inhibitors.
    Salameh BA; Cumpstey I; Sundin A; Leffler H; Nilsson UJ
    Bioorg Med Chem; 2010 Jul; 18(14):5367-78. PubMed ID: 20538469
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Lactulose as a novel template for anticancer drug development targeting galectins.
    Kishor C; Ross RL; Blanchard H
    Chem Biol Drug Des; 2018 Oct; 92(4):1801-1808. PubMed ID: 29888844
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Synthesis, Structure-Activity Relationships, and In Vivo Evaluation of Novel Tetrahydropyran-Based Thiodisaccharide Mimics as Galectin-3 Inhibitors.
    Xu L; Hartz RA; Beno BR; Ghosh K; Shukla JK; Kumar A; Patel D; Kalidindi N; Lemos N; Gautam SS; Kumar A; Ellsworth BA; Shah D; Sale H; Cheng D; Regueiro-Ren A
    J Med Chem; 2021 May; 64(10):6634-6655. PubMed ID: 33988358
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Thiodigalactoside-Bovine Serum Albumin Conjugates as High-Potency Inhibitors of Galectin-3: An Outstanding Example of Multivalent Presentation of Small Molecule Inhibitors.
    Zhang H; Laaf D; Elling L; Pieters RJ
    Bioconjug Chem; 2018 Apr; 29(4):1266-1275. PubMed ID: 29474087
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Synthesis and evaluation of new thiodigalactoside-based chemical probes to label galectin-3.
    van Scherpenzeel M; Moret EE; Ballell L; Liskamp RM; Nilsson UJ; Leffler H; Pieters RJ
    Chembiochem; 2009 Jul; 10(10):1724-33. PubMed ID: 19492387
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Systematic Tuning of Fluoro-galectin-3 Interactions Provides Thiodigalactoside Derivatives with Single-Digit nM Affinity and High Selectivity.
    Peterson K; Kumar R; Stenström O; Verma P; Verma PR; Håkansson M; Kahl-Knutsson B; Zetterberg F; Leffler H; Akke M; Logan DT; Nilsson UJ
    J Med Chem; 2018 Feb; 61(3):1164-1175. PubMed ID: 29284090
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Screening for galectin-3 inhibitors from synthetic lacto-N-biose libraries using microscale affinity chromatography coupled to mass spectrometry.
    Fort S; Kim HS; Hindsgaul O
    J Org Chem; 2006 Sep; 71(19):7146-54. PubMed ID: 16958507
    [TBL] [Abstract][Full Text] [Related]  

  • 11. A Selective Galactose-Coumarin-Derived Galectin-3 Inhibitor Demonstrates Involvement of Galectin-3-glycan Interactions in a Pulmonary Fibrosis Model.
    Rajput VK; MacKinnon A; Mandal S; Collins P; Blanchard H; Leffler H; Sethi T; Schambye H; Mukhopadhyay B; Nilsson UJ
    J Med Chem; 2016 Sep; 59(17):8141-7. PubMed ID: 27500311
    [TBL] [Abstract][Full Text] [Related]  

  • 12. C2-symmetrical thiodigalactoside bis-benzamido derivatives as high-affinity inhibitors of galectin-3: efficient lectin inhibition through double arginine-arene interactions.
    Cumpstey I; Sundin A; Leffler H; Nilsson UJ
    Angew Chem Int Ed Engl; 2005 Aug; 44(32):5110-2. PubMed ID: 16007713
    [No Abstract]   [Full Text] [Related]  

  • 13. Molecular Recognition of a Thomsen-Friedenreich Antigen Mimetic Targeting Human Galectin-3.
    Santarsia S; Grosso AS; Trovão F; Jiménez-Barbero J; Carvalho AL; Nativi C; Marcelo F
    ChemMedChem; 2018 Oct; 13(19):2030-2036. PubMed ID: 30094951
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Elucidation of Hydrogen Bonding Patterns in Ligand-Free, Lactose- and Glycerol-Bound Galectin-3C by Neutron Crystallography to Guide Drug Design.
    Manzoni F; Wallerstein J; Schrader TE; Ostermann A; Coates L; Akke M; Blakeley MP; Oksanen E; Logan DT
    J Med Chem; 2018 May; 61(10):4412-4420. PubMed ID: 29672051
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Thermodynamics of bovine spleen galectin-1 binding to disaccharides: correlation with structure and its effect on oligomerization at the denaturation temperature.
    Schwarz FP; Ahmed H; Bianchet MA; Amzel LM; Vasta GR
    Biochemistry; 1998 Apr; 37(17):5867-77. PubMed ID: 9558320
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Structures of the Erythrina corallodendron lectin and of its complexes with mono- and disaccharides.
    Elgavish S; Shaanan B
    J Mol Biol; 1998 Apr; 277(4):917-32. PubMed ID: 9545381
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Structural and thermodynamic studies on cation-Pi interactions in lectin-ligand complexes: high-affinity galectin-3 inhibitors through fine-tuning of an arginine-arene interaction.
    Sörme P; Arnoux P; Kahl-Knutsson B; Leffler H; Rini JM; Nilsson UJ
    J Am Chem Soc; 2005 Feb; 127(6):1737-43. PubMed ID: 15701008
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Tuning the preference of thiodigalactoside- and lactosamine-based ligands to galectin-3 over galectin-1.
    van Hattum H; Branderhorst HM; Moret EE; Nilsson UJ; Leffler H; Pieters RJ
    J Med Chem; 2013 Feb; 56(3):1350-4. PubMed ID: 23281927
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Protein subtype-targeting through ligand epimerization: talose-selectivity of galectin-4 and galectin-8.
    Oberg CT; Blanchard H; Leffler H; Nilsson UJ
    Bioorg Med Chem Lett; 2008 Jul; 18(13):3691-4. PubMed ID: 18539029
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Binding free energy calculations of galectin-3-ligand interactions.
    Mandal TK; Mukhopadhyay C
    Protein Eng; 2002 Dec; 15(12):979-86. PubMed ID: 12601137
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.