BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

207 related articles for article (PubMed ID: 23873119)

  • 1. A gene-gene interaction between polymorphisms in the OCT2 and MATE1 genes influences the renal clearance of metformin.
    Christensen MM; Pedersen RS; Stage TB; Brasch-Andersen C; Nielsen F; Damkier P; Beck-Nielsen H; Brøsen K
    Pharmacogenet Genomics; 2013 Oct; 23(10):526-34. PubMed ID: 23873119
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Effect of genetic variation in the organic cation transporter 2 on the renal elimination of metformin.
    Chen Y; Li S; Brown C; Cheatham S; Castro RA; Leabman MK; Urban TJ; Chen L; Yee SW; Choi JH; Huang Y; Brett CM; Burchard EG; Giacomini KM
    Pharmacogenet Genomics; 2009 Jul; 19(7):497-504. PubMed ID: 19483665
    [TBL] [Abstract][Full Text] [Related]  

  • 3. OCT2 polymorphisms and in-vivo renal functional consequence: studies with metformin and cimetidine.
    Wang ZJ; Yin OQ; Tomlinson B; Chow MS
    Pharmacogenet Genomics; 2008 Jul; 18(7):637-45. PubMed ID: 18551044
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The MATE1 rs2289669 polymorphism affects the renal clearance of metformin following ranitidine treatment.
    Cho SK; Chung JY
    Int J Clin Pharmacol Ther; 2016 Apr; 54(4):253-62. PubMed ID: 26784938
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The effect of novel promoter variants in MATE1 and MATE2 on the pharmacokinetics and pharmacodynamics of metformin.
    Stocker SL; Morrissey KM; Yee SW; Castro RA; Xu L; Dahlin A; Ramirez AH; Roden DM; Wilke RA; McCarty CA; Davis RL; Brett CM; Giacomini KM
    Clin Pharmacol Ther; 2013 Feb; 93(2):186-94. PubMed ID: 23267855
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Influences of organic cation transporter polymorphisms on the population pharmacokinetics of metformin in healthy subjects.
    Yoon H; Cho HY; Yoo HD; Kim SM; Lee YB
    AAPS J; 2013 Apr; 15(2):571-80. PubMed ID: 23417334
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Polymorphism of organic cation transporter 2 improves glucose-lowering effect of metformin via influencing its pharmacokinetics in Chinese type 2 diabetic patients.
    Hou W; Zhang D; Lu W; Zheng T; Wan L; Li Q; Bao Y; Liu F; Jia W
    Mol Diagn Ther; 2015 Feb; 19(1):25-33. PubMed ID: 25573751
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The effects of genetic polymorphisms in the organic cation transporters OCT1, OCT2, and OCT3 on the renal clearance of metformin.
    Tzvetkov MV; Vormfelde SV; Balen D; Meineke I; Schmidt T; Sehrt D; Sabolić I; Koepsell H; Brockmöller J
    Clin Pharmacol Ther; 2009 Sep; 86(3):299-306. PubMed ID: 19536068
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Trimethoprim-metformin interaction and its genetic modulation by OCT2 and MATE1 transporters.
    Grün B; Kiessling MK; Burhenne J; Riedel KD; Weiss J; Rauch G; Haefeli WE; Czock D
    Br J Clin Pharmacol; 2013 Nov; 76(5):787-96. PubMed ID: 23305245
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Clinical pharmacokinetics of metformin.
    Graham GG; Punt J; Arora M; Day RO; Doogue MP; Duong JK; Furlong TJ; Greenfield JR; Greenup LC; Kirkpatrick CM; Ray JE; Timmins P; Williams KM
    Clin Pharmacokinet; 2011 Feb; 50(2):81-98. PubMed ID: 21241070
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Genetic variants of the organic cation transporter 2 influence the disposition of metformin.
    Song IS; Shin HJ; Shim EJ; Jung IS; Kim WY; Shon JH; Shin JG
    Clin Pharmacol Ther; 2008 Nov; 84(5):559-62. PubMed ID: 18401339
    [TBL] [Abstract][Full Text] [Related]  

  • 12. A drug-drug interaction study to evaluate the impact of peficitinib on OCT1- and MATE1-mediated transport of metformin in healthy volunteers.
    Shibata M; Toyoshima J; Kaneko Y; Oda K; Nishimura T
    Eur J Clin Pharmacol; 2020 Aug; 76(8):1135-1141. PubMed ID: 32472157
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Pharmacogenetics meets metabolomics: discovery of tryptophan as a new endogenous OCT2 substrate related to metformin disposition.
    Song IS; Lee DY; Shin MH; Kim H; Ahn YG; Park I; Kim KH; Kind T; Shin JG; Fiehn O; Liu KH
    PLoS One; 2012; 7(5):e36637. PubMed ID: 22590580
    [TBL] [Abstract][Full Text] [Related]  

  • 14. N(1)-methylnicotinamide as an endogenous probe for drug interactions by renal cation transporters: studies on the metformin-trimethoprim interaction.
    Müller F; Pontones CA; Renner B; Mieth M; Hoier E; Auge D; Maas R; Zolk O; Fromm MF
    Eur J Clin Pharmacol; 2015 Jan; 71(1):85-94. PubMed ID: 25552403
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Genetic variation in the multidrug and toxin extrusion 1 transporter protein influences the glucose-lowering effect of metformin in patients with diabetes: a preliminary study.
    Becker ML; Visser LE; van Schaik RH; Hofman A; Uitterlinden AG; Stricker BH
    Diabetes; 2009 Mar; 58(3):745-9. PubMed ID: 19228809
    [TBL] [Abstract][Full Text] [Related]  

  • 16. SLC22A2 gene 808 G/T variant is related to plasma lactate concentration in Chinese type 2 diabetics treated with metformin.
    Li Q; Liu F; Zheng TS; Tang JL; Lu HJ; Jia WP
    Acta Pharmacol Sin; 2010 Feb; 31(2):184-90. PubMed ID: 20139901
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Human multidrug and toxin extrusion 1 (MATE1/SLC47A1) transporter: functional characterization, interaction with OCT2 (SLC22A2), and single nucleotide polymorphisms.
    Meyer zu Schwabedissen HE; Verstuyft C; Kroemer HK; Becquemont L; Kim RB
    Am J Physiol Renal Physiol; 2010 Apr; 298(4):F997-F1005. PubMed ID: 20053795
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Pregnancy Increases the Renal Secretion of N
    Bergagnini-Kolev MC; Hebert MF; Easterling TR; Lin YS
    Drug Metab Dispos; 2017 Mar; 45(3):325-329. PubMed ID: 28069720
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Steady-state pharmacokinetics of metformin is independent of the OCT1 genotype in healthy volunteers.
    Christensen MMH; Højlund K; Hother-Nielsen O; Stage TB; Damkier P; Beck-Nielsen H; Brøsen K
    Eur J Clin Pharmacol; 2015 Jun; 71(6):691-697. PubMed ID: 25939711
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Association of genetic variation in the organic cation transporters OCT1, OCT2 and multidrug and toxin extrusion 1 transporter protein genes with the gastrointestinal side effects and lower BMI in metformin-treated type 2 diabetes patients.
    Tarasova L; Kalnina I; Geldnere K; Bumbure A; Ritenberga R; Nikitina-Zake L; Fridmanis D; Vaivade I; Pirags V; Klovins J
    Pharmacogenet Genomics; 2012 Sep; 22(9):659-66. PubMed ID: 22735389
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.