BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

243 related articles for article (PubMed ID: 23877677)

  • 1. Structures of the class D Carbapenemases OXA-23 and OXA-146: mechanistic basis of activity against carbapenems, extended-spectrum cephalosporins, and aztreonam.
    Kaitany KC; Klinger NV; June CM; Ramey ME; Bonomo RA; Powers RA; Leonard DA
    Antimicrob Agents Chemother; 2013 Oct; 57(10):4848-55. PubMed ID: 23877677
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Multiple substitutions lead to increased loop flexibility and expanded specificity in
    Harper TM; June CM; Taracila MA; Bonomo RA; Powers RA; Leonard DA
    Biochem J; 2018 Jan; 475(1):273-288. PubMed ID: 29229762
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Structural basis of activity against aztreonam and extended spectrum cephalosporins for two carbapenem-hydrolyzing class D β-lactamases from Acinetobacter baumannii.
    Mitchell JM; Clasman JR; June CM; Kaitany KC; LaFleur JR; Taracila MA; Klinger NV; Bonomo RA; Wymore T; Szarecka A; Powers RA; Leonard DA
    Biochemistry; 2015 Mar; 54(10):1976-87. PubMed ID: 25710192
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Structural Basis for Different Substrate Profiles of Two Closely Related Class D β-Lactamases and Their Inhibition by Halogens.
    Stojanoski V; Chow DC; Fryszczyn B; Hu L; Nordmann P; Poirel L; Sankaran B; Prasad BV; Palzkill T
    Biochemistry; 2015 Jun; 54(21):3370-80. PubMed ID: 25938261
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Structural and Biochemical Features of OXA-517: a Carbapenem and Expanded-Spectrum Cephalosporin Hydrolyzing OXA-48 Variant.
    Dabos L; Raczynska JE; Bogaerts P; Zavala A; Girlich D; Bonnin RA; Dortet L; Peyrat A; Retailleau P; Iorga BI; Jaskólski M; Glupczynski Y; Naas T
    Antimicrob Agents Chemother; 2023 Feb; 67(2):e0109522. PubMed ID: 36648230
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Evolution to carbapenem-hydrolyzing activity in noncarbapenemase class D β-lactamase OXA-10 by rational protein design.
    De Luca F; Benvenuti M; Carboni F; Pozzi C; Rossolini GM; Mangani S; Docquier JD
    Proc Natl Acad Sci U S A; 2011 Nov; 108(45):18424-9. PubMed ID: 22042844
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Structural Insights into the Mechanism of Carbapenemase Activity of the OXA-48 β-Lactamase.
    Smith CA; Stewart NK; Toth M; Vakulenko SB
    Antimicrob Agents Chemother; 2019 Oct; 63(10):. PubMed ID: 31358584
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Structures of the class D carbapenemase OXA-24 from Acinetobacter baumannii in complex with doripenem.
    Schneider KD; Ortega CJ; Renck NA; Bonomo RA; Powers RA; Leonard DA
    J Mol Biol; 2011 Mar; 406(4):583-94. PubMed ID: 21215758
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Comparative activities of doripenem versus isolates, mutants, and transconjugants of Enterobacteriaceae and Acinetobacter spp. with characterized beta-lactamases.
    Mushtaq S; Ge Y; Livermore DM
    Antimicrob Agents Chemother; 2004 Apr; 48(4):1313-9. PubMed ID: 15047535
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Conformational flexibility in carbapenem hydrolysis drives substrate specificity of the class D carbapenemase OXA-24/40.
    Mitchell JM; June CM; Baggett VL; Lowe BC; Ruble JF; Bonomo RA; Leonard DA; Powers RA
    J Biol Chem; 2022 Jul; 298(7):102127. PubMed ID: 35709986
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Activity of the β-Lactamase Inhibitor LN-1-255 against Carbapenem-Hydrolyzing Class D β-Lactamases from Acinetobacter baumannii.
    Vázquez-Ucha JC; Maneiro M; Martínez-Guitián M; Buynak J; Bethel CR; Bonomo RA; Bou G; Poza M; González-Bello C; Beceiro A
    Antimicrob Agents Chemother; 2017 Nov; 61(11):. PubMed ID: 28807908
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Class D β-lactamases: are they all carbapenemases?
    Antunes NT; Lamoureaux TL; Toth M; Stewart NK; Frase H; Vakulenko SB
    Antimicrob Agents Chemother; 2014; 58(4):2119-25. PubMed ID: 24468778
    [TBL] [Abstract][Full Text] [Related]  

  • 13. WCK 4234, a novel diazabicyclooctane potentiating carbapenems against Enterobacteriaceae, Pseudomonas and Acinetobacter with class A, C and D β-lactamases.
    Mushtaq S; Vickers A; Woodford N; Livermore DM
    J Antimicrob Chemother; 2017 Jun; 72(6):1688-1695. PubMed ID: 28333319
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Expanded Substrate Activity of OXA-24/40 in Carbapenem-Resistant Acinetobacter baumannii Involves Enhanced Binding Loop Flexibility.
    Staude MW; Leonard DA; Peng JW
    Biochemistry; 2016 Nov; 55(47):6535-6544. PubMed ID: 27783477
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Molecular docking, dynamics and free energy analyses of
    Ramachandran B; Jeyakanthan J; Lopes BS
    J Med Microbiol; 2020 Aug; 69(8):1062-1078. PubMed ID: 32773005
    [No Abstract]   [Full Text] [Related]  

  • 16. Characterization of OXA-25, OXA-26, and OXA-27, molecular class D beta-lactamases associated with carbapenem resistance in clinical isolates of Acinetobacter baumannii.
    Afzal-Shah M; Woodford N; Livermore DM
    Antimicrob Agents Chemother; 2001 Feb; 45(2):583-8. PubMed ID: 11158758
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Crystal structure of carbapenemase OXA-58 from Acinetobacter baumannii.
    Smith CA; Antunes NT; Toth M; Vakulenko SB
    Antimicrob Agents Chemother; 2014; 58(4):2135-43. PubMed ID: 24468777
    [TBL] [Abstract][Full Text] [Related]  

  • 18. OXA-427, a new plasmid-borne carbapenem-hydrolysing class D β-lactamase in Enterobacteriaceae.
    Bogaerts P; Naas T; Saegeman V; Bonnin RA; Schuermans A; Evrard S; Bouchahrouf W; Jove T; Tande D; de Bolle X; Huang TD; Dortet L; Glupczynski Y
    J Antimicrob Chemother; 2017 Sep; 72(9):2469-2477. PubMed ID: 28859446
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Substrate Specificity of OXA-48 after β5-β6 Loop Replacement.
    Dabos L; Zavala A; Bonnin RA; Beckstein O; Retailleau P; Iorga BI; Naas T
    ACS Infect Dis; 2020 May; 6(5):1032-1043. PubMed ID: 32156115
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Mechanistic Basis of OXA-48-like β-Lactamases' Hydrolysis of Carbapenems.
    Stojanoski V; Hu L; Sankaran B; Wang F; Tao P; Prasad BVV; Palzkill T
    ACS Infect Dis; 2021 Feb; 7(2):445-460. PubMed ID: 33492952
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.