These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

295 related articles for article (PubMed ID: 23878237)

  • 1. Capturing the mutational landscape of the beta-lactamase TEM-1.
    Jacquier H; Birgy A; Le Nagard H; Mechulam Y; Schmitt E; Glodt J; Bercot B; Petit E; Poulain J; Barnaud G; Gros PA; Tenaillon O
    Proc Natl Acad Sci U S A; 2013 Aug; 110(32):13067-72. PubMed ID: 23878237
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A secondary drug resistance mutation of TEM-1 beta-lactamase that suppresses misfolding and aggregation.
    Sideraki V; Huang W; Palzkill T; Gilbert HF
    Proc Natl Acad Sci U S A; 2001 Jan; 98(1):283-8. PubMed ID: 11114163
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Network models of TEM β-lactamase mutations coevolving under antibiotic selection show modular structure and anticipate evolutionary trajectories.
    Guthrie VB; Allen J; Camps M; Karchin R
    PLoS Comput Biol; 2011 Sep; 7(9):e1002184. PubMed ID: 21966264
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Quantitative Description of a Protein Fitness Landscape Based on Molecular Features.
    Meini MR; Tomatis PE; Weinreich DM; Vila AJ
    Mol Biol Evol; 2015 Jul; 32(7):1774-87. PubMed ID: 25767204
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Enzyme Efficiency but Not Thermostability Drives Cefotaxime Resistance Evolution in TEM-1 β-Lactamase.
    Knies JL; Cai F; Weinreich DM
    Mol Biol Evol; 2017 May; 34(5):1040-1054. PubMed ID: 28087769
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Predicting the emergence of antibiotic resistance by directed evolution and structural analysis.
    Orencia MC; Yoon JS; Ness JE; Stemmer WP; Stevens RC
    Nat Struct Biol; 2001 Mar; 8(3):238-42. PubMed ID: 11224569
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Back mutations to the TEM-1 beta-lactamase from TRC-1 lead to restored sensitivity to clavulanic acid.
    Thomson CJ; Amyes SG
    J Med Microbiol; 1995 Jun; 42(6):429-32. PubMed ID: 7791208
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The Fitness of Beta-Lactamase Mutants Depends Nonlinearly on Resistance Level at Sublethal Antibiotic Concentrations.
    Farr AD; Pesce D; Das SG; Zwart MP; de Visser JAGM
    mBio; 2023 Jun; 14(3):e0009823. PubMed ID: 37129484
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Initial mutations direct alternative pathways of protein evolution.
    Salverda ML; Dellus E; Gorter FA; Debets AJ; van der Oost J; Hoekstra RF; Tawfik DS; de Visser JA
    PLoS Genet; 2011 Mar; 7(3):e1001321. PubMed ID: 21408208
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Mutation supply and the repeatability of selection for antibiotic resistance.
    van Dijk T; Hwang S; Krug J; de Visser JAGM; Zwart MP
    Phys Biol; 2017 Aug; 14(5):055005. PubMed ID: 28699625
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Shifting Fitness and Epistatic Landscapes Reflect Trade-offs along an Evolutionary Pathway.
    Steinberg B; Ostermeier M
    J Mol Biol; 2016 Jul; 428(13):2730-43. PubMed ID: 27173379
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Darwinian evolution can follow only very few mutational paths to fitter proteins.
    Weinreich DM; Delaney NF; Depristo MA; Hartl DL
    Science; 2006 Apr; 312(5770):111-4. PubMed ID: 16601193
    [TBL] [Abstract][Full Text] [Related]  

  • 13. SHV-129: A Gateway to Global Suppressors in the SHV β-Lactamase Family?
    Winkler ML; Bonomo RA
    Mol Biol Evol; 2016 Feb; 33(2):429-41. PubMed ID: 26531195
    [TBL] [Abstract][Full Text] [Related]  

  • 14. A comprehensive, high-resolution map of a gene's fitness landscape.
    Firnberg E; Labonte JW; Gray JJ; Ostermeier M
    Mol Biol Evol; 2014 Jun; 31(6):1581-92. PubMed ID: 24567513
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Substitution of Met-69 by Ala or Gly in TEM-1 beta-lactamase confer an increased susceptibility to clavulanic acid and other inhibitors.
    Madec S; Blin C; Krishnamoorthy R; Picard B; Chaibi el B; Fouchereau-Péron M; Labia R
    FEMS Microbiol Lett; 2002 May; 211(1):13-6. PubMed ID: 12052544
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A natural polymorphism in beta-lactamase is a global suppressor.
    Huang W; Palzkill T
    Proc Natl Acad Sci U S A; 1997 Aug; 94(16):8801-6. PubMed ID: 9238058
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Environmental changes bridge evolutionary valleys.
    Steinberg B; Ostermeier M
    Sci Adv; 2016 Jan; 2(1):e1500921. PubMed ID: 26844293
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Unraveling the causes of adaptive benefits of synonymous mutations in TEM-1 β-lactamase.
    Zwart MP; Schenk MF; Hwang S; Koopmanschap B; de Lange N; van de Pol L; Nga TTT; Szendro IG; Krug J; de Visser JAGM
    Heredity (Edinb); 2018 Nov; 121(5):406-421. PubMed ID: 29967397
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Adaptive benefits from small mutation supplies in an antibiotic resistance enzyme.
    Salverda MLM; Koomen J; Koopmanschap B; Zwart MP; de Visser JAGM
    Proc Natl Acad Sci U S A; 2017 Nov; 114(48):12773-12778. PubMed ID: 29133391
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Selection of variants of the TEM-1 beta-lactamase, encoded by a plasmid of clinical origin, with increased resistance to beta-lactamase inhibitors.
    Thomson CJ; Amyes SG
    J Antimicrob Chemother; 1993 May; 31(5):655-64. PubMed ID: 8392995
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.