These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

153 related articles for article (PubMed ID: 23883151)

  • 1. Temporally overlapped but uncoupled motions in dihydrofolate reductase catalysis.
    Liu CT; Wang L; Goodey NM; Hanoian P; Benkovic SJ
    Biochemistry; 2013 Aug; 52(32):5332-4. PubMed ID: 23883151
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The role of large-scale motions in catalysis by dihydrofolate reductase.
    Loveridge EJ; Tey LH; Behiry EM; Dawson WM; Evans RM; Whittaker SB; Günther UL; Williams C; Crump MP; Allemann RK
    J Am Chem Soc; 2011 Dec; 133(50):20561-70. PubMed ID: 22060818
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Protein motions and the activation of the CH bond catalyzed by dihydrofolate reductase.
    Francis K; Kohen A
    Curr Opin Chem Biol; 2014 Aug; 21():19-24. PubMed ID: 24742825
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Impact of distal mutations on the network of coupled motions correlated to hydride transfer in dihydrofolate reductase.
    Wong KF; Selzer T; Benkovic SJ; Hammes-Schiffer S
    Proc Natl Acad Sci U S A; 2005 May; 102(19):6807-12. PubMed ID: 15811945
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Multiple intermediates, diverse conformations, and cooperative conformational changes underlie the catalytic hydride transfer reaction of dihydrofolate reductase.
    Arora K; Brooks CL
    Top Curr Chem; 2013; 337():165-87. PubMed ID: 23420416
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Coupling of protein motions and hydrogen transfer during catalysis by Escherichia coli dihydrofolate reductase.
    Swanwick RS; Maglia G; Tey LH; Allemann RK
    Biochem J; 2006 Feb; 394(Pt 1):259-65. PubMed ID: 16241906
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Solvent effects on catalysis by Escherichia coli dihydrofolate reductase.
    Loveridge EJ; Tey LH; Allemann RK
    J Am Chem Soc; 2010 Jan; 132(3):1137-43. PubMed ID: 20047317
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Cryo-kinetics Reveal Dynamic Effects on the Chemistry of Human Dihydrofolate Reductase.
    Adesina AS; Luk LYP; Allemann RK
    Chembiochem; 2021 Jul; 22(14):2410-2414. PubMed ID: 33876533
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Backbone dynamics in dihydrofolate reductase complexes: role of loop flexibility in the catalytic mechanism.
    Osborne MJ; Schnell J; Benkovic SJ; Dyson HJ; Wright PE
    Biochemistry; 2001 Aug; 40(33):9846-59. PubMed ID: 11502178
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Catalysis by dihydrofolate reductase and other enzymes arises from electrostatic preorganization, not conformational motions.
    Adamczyk AJ; Cao J; Kamerlin SC; Warshel A
    Proc Natl Acad Sci U S A; 2011 Aug; 108(34):14115-20. PubMed ID: 21831831
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Evidence that a 'dynamic knockout' in Escherichia coli dihydrofolate reductase does not affect the chemical step of catalysis.
    Loveridge EJ; Behiry EM; Guo J; Allemann RK
    Nat Chem; 2012 Mar; 4(4):292-7. PubMed ID: 22437714
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Probing coupled motions in enzymatic hydrogen tunnelling reactions.
    Allemann RK; Evans RM; Loveridge EJ
    Biochem Soc Trans; 2009 Apr; 37(Pt 2):349-53. PubMed ID: 19290860
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Structure, dynamics, and catalytic function of dihydrofolate reductase.
    Schnell JR; Dyson HJ; Wright PE
    Annu Rev Biophys Biomol Struct; 2004; 33():119-40. PubMed ID: 15139807
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Solvent effects on environmentally coupled hydrogen tunnelling during catalysis by dihydrofolate reductase from Thermotoga maritima.
    Loveridge EJ; Evans RM; Allemann RK
    Chemistry; 2008; 14(34):10782-8. PubMed ID: 18924193
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Protein motions and dynamic effects in enzyme catalysis.
    Luk LY; Loveridge EJ; Allemann RK
    Phys Chem Chem Phys; 2015 Dec; 17(46):30817-27. PubMed ID: 25854702
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A dynamic knockout reveals that conformational fluctuations influence the chemical step of enzyme catalysis.
    Bhabha G; Lee J; Ekiert DC; Gam J; Wilson IA; Dyson HJ; Benkovic SJ; Wright PE
    Science; 2011 Apr; 332(6026):234-8. PubMed ID: 21474759
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Reaction-path energetics and kinetics of the hydride transfer reaction catalyzed by dihydrofolate reductase.
    Garcia-Viloca M; Truhlar DG; Gao J
    Biochemistry; 2003 Nov; 42(46):13558-75. PubMed ID: 14622003
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Distal Regions Regulate Dihydrofolate Reductase-Ligand Interactions.
    Goldstein M; Goodey NM
    Methods Mol Biol; 2021; 2253():185-219. PubMed ID: 33315225
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Conformational relaxation following hydride transfer plays a limiting role in dihydrofolate reductase catalysis.
    Boehr DD; Dyson HJ; Wright PE
    Biochemistry; 2008 Sep; 47(35):9227-33. PubMed ID: 18690714
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Relating protein motion to catalysis.
    Hammes-Schiffer S; Benkovic SJ
    Annu Rev Biochem; 2006; 75():519-41. PubMed ID: 16756501
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.