These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

427 related articles for article (PubMed ID: 23888040)

  • 1. Nuclear PTEN controls DNA repair and sensitivity to genotoxic stress.
    Bassi C; Ho J; Srikumar T; Dowling RJ; Gorrini C; Miller SJ; Mak TW; Neel BG; Raught B; Stambolic V
    Science; 2013 Jul; 341(6144):395-9. PubMed ID: 23888040
    [TBL] [Abstract][Full Text] [Related]  

  • 2. ATM-mediated PTEN phosphorylation promotes PTEN nuclear translocation and autophagy in response to DNA-damaging agents in cancer cells.
    Chen JH; Zhang P; Chen WD; Li DD; Wu XQ; Deng R; Jiao L; Li X; Ji J; Feng GK; Zeng YX; Jiang JW; Zhu XF
    Autophagy; 2015; 11(2):239-52. PubMed ID: 25701194
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Cell cycle checkpoint defects contribute to genomic instability in PTEN deficient cells independent of DNA DSB repair.
    Gupta A; Yang Q; Pandita RK; Hunt CR; Xiang T; Misri S; Zeng S; Pagan J; Jeffery J; Puc J; Kumar R; Feng Z; Powell SN; Bhat A; Yaguchi T; Wadhwa R; Kaul SC; Parsons R; Khanna KK; Pandita TK
    Cell Cycle; 2009 Jul; 8(14):2198-210. PubMed ID: 19502790
    [TBL] [Abstract][Full Text] [Related]  

  • 4. MRE11 promotes AKT phosphorylation in direct response to DNA double-strand breaks.
    Fraser M; Harding SM; Zhao H; Coackley C; Durocher D; Bristow RG
    Cell Cycle; 2011 Jul; 10(13):2218-32. PubMed ID: 21623170
    [TBL] [Abstract][Full Text] [Related]  

  • 5. PTEN nuclear localization is regulated by oxidative stress and mediates p53-dependent tumor suppression.
    Chang CJ; Mulholland DJ; Valamehr B; Mosessian S; Sellers WR; Wu H
    Mol Cell Biol; 2008 May; 28(10):3281-9. PubMed ID: 18332125
    [TBL] [Abstract][Full Text] [Related]  

  • 6. A cytoplasmic ATM-TRAF6-cIAP1 module links nuclear DNA damage signaling to ubiquitin-mediated NF-κB activation.
    Hinz M; Stilmann M; Arslan SÇ; Khanna KK; Dittmar G; Scheidereit C
    Mol Cell; 2010 Oct; 40(1):63-74. PubMed ID: 20932475
    [TBL] [Abstract][Full Text] [Related]  

  • 7. A positive role for c-Abl in Atm and Atr activation in DNA damage response.
    Wang X; Zeng L; Wang J; Chau JF; Lai KP; Jia D; Poonepalli A; Hande MP; Liu H; He G; He L; Li B
    Cell Death Differ; 2011 Jan; 18(1):5-15. PubMed ID: 20798688
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Chromatin PTEN is involved in DNA damage response partly through regulating Rad52 sumoylation.
    Choi BH; Chen Y; Dai W
    Cell Cycle; 2013 Nov; 12(21):3442-7. PubMed ID: 24047694
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Doxorubicin activates ATM-dependent phosphorylation of multiple downstream targets in part through the generation of reactive oxygen species.
    Kurz EU; Douglas P; Lees-Miller SP
    J Biol Chem; 2004 Dec; 279(51):53272-81. PubMed ID: 15489221
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Resistance to DNA-damaging treatment in non-small cell lung cancer tumor-initiating cells involves reduced DNA-PK/ATM activation and diminished cell cycle arrest.
    Lundholm L; Hååg P; Zong D; Juntti T; Mörk B; Lewensohn R; Viktorsson K
    Cell Death Dis; 2013 Jan; 4(1):e478. PubMed ID: 23370278
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Biochemical and cellular characterization of VRX0466617, a novel and selective inhibitor for the checkpoint kinase Chk2.
    Carlessi L; Buscemi G; Larson G; Hong Z; Wu JZ; Delia D
    Mol Cancer Ther; 2007 Mar; 6(3):935-44. PubMed ID: 17363488
    [TBL] [Abstract][Full Text] [Related]  

  • 12. PTEN induces cell cycle arrest by decreasing the level and nuclear localization of cyclin D1.
    Radu A; Neubauer V; Akagi T; Hanafusa H; Georgescu MM
    Mol Cell Biol; 2003 Sep; 23(17):6139-49. PubMed ID: 12917336
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Characterization of nuclear PTEN and its post translational modifications.
    Ho J; Bassi C; Stambolic V
    Methods; 2015 May; 77-78():104-11. PubMed ID: 25616216
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Role of autophagy in chemoresistance: regulation of the ATM-mediated DNA-damage signaling pathway through activation of DNA-PKcs and PARP-1.
    Yoon JH; Ahn SG; Lee BH; Jung SH; Oh SH
    Biochem Pharmacol; 2012 Mar; 83(6):747-57. PubMed ID: 22226932
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Clustered DNA damage induces pan-nuclear H2AX phosphorylation mediated by ATM and DNA-PK.
    Meyer B; Voss KO; Tobias F; Jakob B; Durante M; Taucher-Scholz G
    Nucleic Acids Res; 2013 Jul; 41(12):6109-18. PubMed ID: 23620287
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Ku70/80 modulates ATM and ATR signaling pathways in response to DNA double strand breaks.
    Tomimatsu N; Tahimic CG; Otsuki A; Burma S; Fukuhara A; Sato K; Shiota G; Oshimura M; Chen DJ; Kurimasa A
    J Biol Chem; 2007 Apr; 282(14):10138-45. PubMed ID: 17272272
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Role for KAP1 serine 824 phosphorylation and sumoylation/desumoylation switch in regulating KAP1-mediated transcriptional repression.
    Li X; Lee YK; Jeng JC; Yen Y; Schultz DC; Shih HM; Ann DK
    J Biol Chem; 2007 Dec; 282(50):36177-89. PubMed ID: 17942393
    [TBL] [Abstract][Full Text] [Related]  

  • 18. An ATM/TRIM37/NEMO Axis Counteracts Genotoxicity by Activating Nuclear-to-Cytoplasmic NF-κB Signaling.
    Wu G; Song L; Zhu J; Hu Y; Cao L; Tan Z; Zhang S; Li Z; Li J
    Cancer Res; 2018 Nov; 78(22):6399-6412. PubMed ID: 30254148
    [TBL] [Abstract][Full Text] [Related]  

  • 19. PTEN deficiency sensitizes endometrioid endometrial cancer to compound PARP-PI3K inhibition but not PARP inhibition as monotherapy.
    Bian X; Gao J; Luo F; Rui C; Zheng T; Wang D; Wang Y; Roberts TM; Liu P; Zhao JJ; Cheng H
    Oncogene; 2018 Jan; 37(3):341-351. PubMed ID: 28945226
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Sequential modification of NEMO/IKKgamma by SUMO-1 and ubiquitin mediates NF-kappaB activation by genotoxic stress.
    Huang TT; Wuerzberger-Davis SM; Wu ZH; Miyamoto S
    Cell; 2003 Nov; 115(5):565-76. PubMed ID: 14651848
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 22.