184 related articles for article (PubMed ID: 23896737)
1. Identification of three novel natural product compounds that activate PXR and CAR and inhibit inflammation.
Kittayaruksakul S; Zhao W; Xu M; Ren S; Lu J; Wang J; Downes M; Evans RM; Venkataramanan R; Chatsudthipong V; Xie W
Pharm Res; 2013 Sep; 30(9):2199-208. PubMed ID: 23896737
[TBL] [Abstract][Full Text] [Related]
2. Effects of atorvastatin metabolites on induction of drug-metabolizing enzymes and membrane transporters through human pregnane X receptor.
Hoffart E; Ghebreghiorghis L; Nussler AK; Thasler WE; Weiss TS; Schwab M; Burk O
Br J Pharmacol; 2012 Mar; 165(5):1595-608. PubMed ID: 21913896
[TBL] [Abstract][Full Text] [Related]
3. Modulation of constitutive androstane receptor (CAR) and pregnane X receptor (PXR) by 6-arylpyrrolo[2,1-d][1,5]benzothiazepine derivatives, ligands of peripheral benzodiazepine receptor (PBR).
Anderson LE; Dring AM; Hamel LD; Stoner MA
Toxicol Lett; 2011 Apr; 202(2):148-54. PubMed ID: 21315811
[TBL] [Abstract][Full Text] [Related]
4. Coordinated roles of pregnane X receptor and constitutive androstane receptor in autoinduction of voriconazole metabolism in mice.
Ohbuchi M; Yoshinari K; Kaneko H; Matsumoto S; Inoue A; Kawamura A; Usui T; Yamazoe Y
Antimicrob Agents Chemother; 2013 Mar; 57(3):1332-8. PubMed ID: 23274663
[TBL] [Abstract][Full Text] [Related]
5. Differential activation of pregnane X receptor and constitutive androstane receptor by buprenorphine in primary human hepatocytes and HepG2 cells.
Li L; Hassan HE; Tolson AH; Ferguson SS; Eddington ND; Wang H
J Pharmacol Exp Ther; 2010 Dec; 335(3):562-71. PubMed ID: 20829393
[TBL] [Abstract][Full Text] [Related]
6. Sterol regulatory element binding protein 1 interacts with pregnane X receptor and constitutive androstane receptor and represses their target genes.
Roth A; Looser R; Kaufmann M; Meyer UA
Pharmacogenet Genomics; 2008 Apr; 18(4):325-37. PubMed ID: 18334917
[TBL] [Abstract][Full Text] [Related]
7. Opposing regulation of cytochrome P450 expression by CAR and PXR in hypothyroid mice.
Park YJ; Lee EK; Lee YK; Park DJ; Jang HC; Moore DD
Toxicol Appl Pharmacol; 2012 Sep; 263(2):131-7. PubMed ID: 22503787
[TBL] [Abstract][Full Text] [Related]
8. Bioactive terpenoids and flavonoids from Ginkgo biloba extract induce the expression of hepatic drug-metabolizing enzymes through pregnane X receptor, constitutive androstane receptor, and aryl hydrocarbon receptor-mediated pathways.
Li L; Stanton JD; Tolson AH; Luo Y; Wang H
Pharm Res; 2009 Apr; 26(4):872-82. PubMed ID: 19034627
[TBL] [Abstract][Full Text] [Related]
9. Endosulfan induces CYP2B6 and CYP3A4 by activating the pregnane X receptor.
Casabar RC; Das PC; Dekrey GK; Gardiner CS; Cao Y; Rose RL; Wallace AD
Toxicol Appl Pharmacol; 2010 Jun; 245(3):335-43. PubMed ID: 20361990
[TBL] [Abstract][Full Text] [Related]
10. A novel distal enhancer module regulated by pregnane X receptor/constitutive androstane receptor is essential for the maximal induction of CYP2B6 gene expression.
Wang H; Faucette S; Sueyoshi T; Moore R; Ferguson S; Negishi M; LeCluyse EL
J Biol Chem; 2003 Apr; 278(16):14146-52. PubMed ID: 12571232
[TBL] [Abstract][Full Text] [Related]
11. Human constitutive androstane receptor mediates induction of CYP2B6 gene expression by phenytoin.
Wang H; Faucette S; Moore R; Sueyoshi T; Negishi M; LeCluyse E
J Biol Chem; 2004 Jul; 279(28):29295-301. PubMed ID: 15123723
[TBL] [Abstract][Full Text] [Related]
12. Valproic acid induces CYP3A4 and MDR1 gene expression by activation of constitutive androstane receptor and pregnane X receptor pathways.
Cerveny L; Svecova L; Anzenbacherova E; Vrzal R; Staud F; Dvorak Z; Ulrichova J; Anzenbacher P; Pavek P
Drug Metab Dispos; 2007 Jul; 35(7):1032-41. PubMed ID: 17392393
[TBL] [Abstract][Full Text] [Related]
13. Thalidomide increases human hepatic cytochrome P450 3A enzymes by direct activation of the pregnane X receptor.
Murayama N; van Beuningen R; Suemizu H; Guillouzo CG; Shibata N; Yajima K; Utoh M; Shimizu M; Chesné C; Nakamura M; Guengerich FP; Houtman R; Yamazaki H
Chem Res Toxicol; 2014 Feb; 27(2):304-308. PubMed ID: 24460184
[TBL] [Abstract][Full Text] [Related]
14. Modulation of pregnane X receptor (PXR) and constitutive androstane receptor (CAR) activation by ursolic acid (UA) attenuates rifampin-isoniazid cytotoxicity.
Chang HY; Chen CJ; Ma WC; Cheng WK; Lin YN; Lee YR; Chen JJ; Lim YP
Phytomedicine; 2017 Dec; 36():37-49. PubMed ID: 29157826
[TBL] [Abstract][Full Text] [Related]
15. The phytoestrogen coumestrol is a naturally occurring antagonist of the human pregnane X receptor.
Wang H; Li H; Moore LB; Johnson MD; Maglich JM; Goodwin B; Ittoop OR; Wisely B; Creech K; Parks DJ; Collins JL; Willson TM; Kalpana GV; Venkatesh M; Xie W; Cho SY; Roboz J; Redinbo M; Moore JT; Mani S
Mol Endocrinol; 2008 Apr; 22(4):838-57. PubMed ID: 18096694
[TBL] [Abstract][Full Text] [Related]
16. The role of constitutive androstane receptor in oxazaphosphorine-mediated induction of drug-metabolizing enzymes in human hepatocytes.
Wang D; Li L; Fuhrman J; Ferguson S; Wang H
Pharm Res; 2011 Aug; 28(8):2034-44. PubMed ID: 21487929
[TBL] [Abstract][Full Text] [Related]
17. Reciprocal activation of xenobiotic response genes by nuclear receptors SXR/PXR and CAR.
Xie W; Barwick JL; Simon CM; Pierce AM; Safe S; Blumberg B; Guzelian PS; Evans RM
Genes Dev; 2000 Dec; 14(23):3014-23. PubMed ID: 11114890
[TBL] [Abstract][Full Text] [Related]
18. Differential regulation of hepatic CYP2B6 and CYP3A4 genes by constitutive androstane receptor but not pregnane X receptor.
Faucette SR; Sueyoshi T; Smith CM; Negishi M; Lecluyse EL; Wang H
J Pharmacol Exp Ther; 2006 Jun; 317(3):1200-9. PubMed ID: 16513849
[TBL] [Abstract][Full Text] [Related]
19. Dehydroepiandrosterone induces human CYP2B6 through the constitutive androstane receptor.
Kohalmy K; Tamási V; Kóbori L; Sárváry E; Pascussi JM; Porrogi P; Rozman D; Prough RA; Meyer UA; Monostory K
Drug Metab Dispos; 2007 Sep; 35(9):1495-501. PubMed ID: 17591676
[TBL] [Abstract][Full Text] [Related]
20. Glucocorticoid receptor enhancement of pregnane X receptor-mediated CYP2B6 regulation in primary human hepatocytes.
Wang H; Faucette SR; Gilbert D; Jolley SL; Sueyoshi T; Negishi M; LeCluyse EL
Drug Metab Dispos; 2003 May; 31(5):620-30. PubMed ID: 12695351
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
