447 related articles for article (PubMed ID: 23900562)
1. Reductive glutamine metabolism is a function of the α-ketoglutarate to citrate ratio in cells.
Fendt SM; Bell EL; Keibler MA; Olenchock BA; Mayers JR; Wasylenko TM; Vokes NI; Guarente L; Vander Heiden MG; Stephanopoulos G
Nat Commun; 2013; 4():2236. PubMed ID: 23900562
[TBL] [Abstract][Full Text] [Related]
2. Hypoxia promotes isocitrate dehydrogenase-dependent carboxylation of α-ketoglutarate to citrate to support cell growth and viability.
Wise DR; Ward PS; Shay JE; Cross JR; Gruber JJ; Sachdeva UM; Platt JM; DeMatteo RG; Simon MC; Thompson CB
Proc Natl Acad Sci U S A; 2011 Dec; 108(49):19611-6. PubMed ID: 22106302
[TBL] [Abstract][Full Text] [Related]
3. Fatty acid labeling from glutamine in hypoxia can be explained by isotope exchange without net reductive isocitrate dehydrogenase (IDH) flux.
Fan J; Kamphorst JJ; Rabinowitz JD; Shlomi T
J Biol Chem; 2013 Oct; 288(43):31363-9. PubMed ID: 24030823
[TBL] [Abstract][Full Text] [Related]
4. Reductive glutamine metabolism by IDH1 mediates lipogenesis under hypoxia.
Metallo CM; Gameiro PA; Bell EL; Mattaini KR; Yang J; Hiller K; Jewell CM; Johnson ZR; Irvine DJ; Guarente L; Kelleher JK; Vander Heiden MG; Iliopoulos O; Stephanopoulos G
Nature; 2011 Nov; 481(7381):380-4. PubMed ID: 22101433
[TBL] [Abstract][Full Text] [Related]
5. Metabolic and mind shifts: from glucose to glutamine and acetate addictions in cancer.
Corbet C; Feron O
Curr Opin Clin Nutr Metab Care; 2015 Jul; 18(4):346-53. PubMed ID: 26001655
[TBL] [Abstract][Full Text] [Related]
6. Quantifying reductive carboxylation flux of glutamine to lipid in a brown adipocyte cell line.
Yoo H; Antoniewicz MR; Stephanopoulos G; Kelleher JK
J Biol Chem; 2008 Jul; 283(30):20621-7. PubMed ID: 18364355
[TBL] [Abstract][Full Text] [Related]
7. Oxidation of alpha-ketoglutarate is required for reductive carboxylation in cancer cells with mitochondrial defects.
Mullen AR; Hu Z; Shi X; Jiang L; Boroughs LK; Kovacs Z; Boriack R; Rakheja D; Sullivan LB; Linehan WM; Chandel NS; DeBerardinis RJ
Cell Rep; 2014 Jun; 7(5):1679-1690. PubMed ID: 24857658
[TBL] [Abstract][Full Text] [Related]
8. Pathway of carbon flow during fatty acid synthesis from lactate and pyruvate in rat adipose tissue.
Patel MS; Jomain-Baum M; Ballard FJ; Hanson RW
J Lipid Res; 1971 Mar; 12(2):179-91. PubMed ID: 4396562
[TBL] [Abstract][Full Text] [Related]
9. Chronic Hypoxia Enhances β-Oxidation-Dependent Electron Transport via Electron Transferring Flavoproteins.
Fuhrmann DC; Olesch C; Kurrle N; Schnütgen F; Zukunft S; Fleming I; Brüne B
Cells; 2019 Feb; 8(2):. PubMed ID: 30781698
[TBL] [Abstract][Full Text] [Related]
10. Glutamine metabolism in AS-30D hepatoma cells. Evidence for its conversion into lipids via reductive carboxylation.
Holleran AL; Briscoe DA; Fiskum G; Kelleher JK
Mol Cell Biochem; 1995 Nov; 152(2):95-101. PubMed ID: 8751155
[TBL] [Abstract][Full Text] [Related]
11. Reductive carboxylation supports redox homeostasis during anchorage-independent growth.
Jiang L; Shestov AA; Swain P; Yang C; Parker SJ; Wang QA; Terada LS; Adams ND; McCabe MT; Pietrak B; Schmidt S; Metallo CM; Dranka BP; Schwartz B; DeBerardinis RJ
Nature; 2016 Apr; 532(7598):255-8. PubMed ID: 27049945
[TBL] [Abstract][Full Text] [Related]
12. Viral effects on metabolism: changes in glucose and glutamine utilization during human cytomegalovirus infection.
Yu Y; Clippinger AJ; Alwine JC
Trends Microbiol; 2011 Jul; 19(7):360-7. PubMed ID: 21570293
[TBL] [Abstract][Full Text] [Related]
13. Cofactor balance by nicotinamide nucleotide transhydrogenase (NNT) coordinates reductive carboxylation and glucose catabolism in the tricarboxylic acid (TCA) cycle.
Gameiro PA; Laviolette LA; Kelleher JK; Iliopoulos O; Stephanopoulos G
J Biol Chem; 2013 May; 288(18):12967-77. PubMed ID: 23504317
[TBL] [Abstract][Full Text] [Related]
14. Neonatal intestinal metabolism.
Kimura RE
Clin Perinatol; 1996 Jun; 23(2):245-63. PubMed ID: 8780904
[TBL] [Abstract][Full Text] [Related]
15. Reductive carboxylation supports growth in tumour cells with defective mitochondria.
Mullen AR; Wheaton WW; Jin ES; Chen PH; Sullivan LB; Cheng T; Yang Y; Linehan WM; Chandel NS; DeBerardinis RJ
Nature; 2011 Nov; 481(7381):385-8. PubMed ID: 22101431
[TBL] [Abstract][Full Text] [Related]
16. Acidosis Drives the Reprogramming of Fatty Acid Metabolism in Cancer Cells through Changes in Mitochondrial and Histone Acetylation.
Corbet C; Pinto A; Martherus R; Santiago de Jesus JP; Polet F; Feron O
Cell Metab; 2016 Aug; 24(2):311-23. PubMed ID: 27508876
[TBL] [Abstract][Full Text] [Related]
17. 13C isotope-assisted methods for quantifying glutamine metabolism in cancer cells.
Zhang J; Ahn WS; Gameiro PA; Keibler MA; Zhang Z; Stephanopoulos G
Methods Enzymol; 2014; 542():369-89. PubMed ID: 24862276
[TBL] [Abstract][Full Text] [Related]
18. Acetyl-CoA and acetylcholine metabolism in nerve terminal compartment of thiamine deficient rat brain.
Jankowska-Kulawy A; Bielarczyk H; Pawełczyk T; Wróblewska M; Szutowicz A
J Neurochem; 2010 Oct; 115(2):333-42. PubMed ID: 20649840
[TBL] [Abstract][Full Text] [Related]
19. Knockdown of both mitochondrial isocitrate dehydrogenase enzymes in pancreatic beta cells inhibits insulin secretion.
MacDonald MJ; Brown LJ; Longacre MJ; Stoker SW; Kendrick MA; Hasan NM
Biochim Biophys Acta; 2013 Nov; 1830(11):5104-11. PubMed ID: 23876293
[TBL] [Abstract][Full Text] [Related]
20. High extracellular lactate causes reductive carboxylation in breast tissue cell lines grown under normoxic conditions.
Brodsky AN; Odenwelder DC; Harcum SW
PLoS One; 2019; 14(6):e0213419. PubMed ID: 31181081
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]