BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

447 related articles for article (PubMed ID: 23900562)

  • 1. Reductive glutamine metabolism is a function of the α-ketoglutarate to citrate ratio in cells.
    Fendt SM; Bell EL; Keibler MA; Olenchock BA; Mayers JR; Wasylenko TM; Vokes NI; Guarente L; Vander Heiden MG; Stephanopoulos G
    Nat Commun; 2013; 4():2236. PubMed ID: 23900562
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Hypoxia promotes isocitrate dehydrogenase-dependent carboxylation of α-ketoglutarate to citrate to support cell growth and viability.
    Wise DR; Ward PS; Shay JE; Cross JR; Gruber JJ; Sachdeva UM; Platt JM; DeMatteo RG; Simon MC; Thompson CB
    Proc Natl Acad Sci U S A; 2011 Dec; 108(49):19611-6. PubMed ID: 22106302
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Fatty acid labeling from glutamine in hypoxia can be explained by isotope exchange without net reductive isocitrate dehydrogenase (IDH) flux.
    Fan J; Kamphorst JJ; Rabinowitz JD; Shlomi T
    J Biol Chem; 2013 Oct; 288(43):31363-9. PubMed ID: 24030823
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Reductive glutamine metabolism by IDH1 mediates lipogenesis under hypoxia.
    Metallo CM; Gameiro PA; Bell EL; Mattaini KR; Yang J; Hiller K; Jewell CM; Johnson ZR; Irvine DJ; Guarente L; Kelleher JK; Vander Heiden MG; Iliopoulos O; Stephanopoulos G
    Nature; 2011 Nov; 481(7381):380-4. PubMed ID: 22101433
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Metabolic and mind shifts: from glucose to glutamine and acetate addictions in cancer.
    Corbet C; Feron O
    Curr Opin Clin Nutr Metab Care; 2015 Jul; 18(4):346-53. PubMed ID: 26001655
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Quantifying reductive carboxylation flux of glutamine to lipid in a brown adipocyte cell line.
    Yoo H; Antoniewicz MR; Stephanopoulos G; Kelleher JK
    J Biol Chem; 2008 Jul; 283(30):20621-7. PubMed ID: 18364355
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Oxidation of alpha-ketoglutarate is required for reductive carboxylation in cancer cells with mitochondrial defects.
    Mullen AR; Hu Z; Shi X; Jiang L; Boroughs LK; Kovacs Z; Boriack R; Rakheja D; Sullivan LB; Linehan WM; Chandel NS; DeBerardinis RJ
    Cell Rep; 2014 Jun; 7(5):1679-1690. PubMed ID: 24857658
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Pathway of carbon flow during fatty acid synthesis from lactate and pyruvate in rat adipose tissue.
    Patel MS; Jomain-Baum M; Ballard FJ; Hanson RW
    J Lipid Res; 1971 Mar; 12(2):179-91. PubMed ID: 4396562
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Chronic Hypoxia Enhances β-Oxidation-Dependent Electron Transport via Electron Transferring Flavoproteins.
    Fuhrmann DC; Olesch C; Kurrle N; Schnütgen F; Zukunft S; Fleming I; Brüne B
    Cells; 2019 Feb; 8(2):. PubMed ID: 30781698
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Glutamine metabolism in AS-30D hepatoma cells. Evidence for its conversion into lipids via reductive carboxylation.
    Holleran AL; Briscoe DA; Fiskum G; Kelleher JK
    Mol Cell Biochem; 1995 Nov; 152(2):95-101. PubMed ID: 8751155
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Reductive carboxylation supports redox homeostasis during anchorage-independent growth.
    Jiang L; Shestov AA; Swain P; Yang C; Parker SJ; Wang QA; Terada LS; Adams ND; McCabe MT; Pietrak B; Schmidt S; Metallo CM; Dranka BP; Schwartz B; DeBerardinis RJ
    Nature; 2016 Apr; 532(7598):255-8. PubMed ID: 27049945
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Viral effects on metabolism: changes in glucose and glutamine utilization during human cytomegalovirus infection.
    Yu Y; Clippinger AJ; Alwine JC
    Trends Microbiol; 2011 Jul; 19(7):360-7. PubMed ID: 21570293
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Cofactor balance by nicotinamide nucleotide transhydrogenase (NNT) coordinates reductive carboxylation and glucose catabolism in the tricarboxylic acid (TCA) cycle.
    Gameiro PA; Laviolette LA; Kelleher JK; Iliopoulos O; Stephanopoulos G
    J Biol Chem; 2013 May; 288(18):12967-77. PubMed ID: 23504317
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Neonatal intestinal metabolism.
    Kimura RE
    Clin Perinatol; 1996 Jun; 23(2):245-63. PubMed ID: 8780904
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Reductive carboxylation supports growth in tumour cells with defective mitochondria.
    Mullen AR; Wheaton WW; Jin ES; Chen PH; Sullivan LB; Cheng T; Yang Y; Linehan WM; Chandel NS; DeBerardinis RJ
    Nature; 2011 Nov; 481(7381):385-8. PubMed ID: 22101431
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Acidosis Drives the Reprogramming of Fatty Acid Metabolism in Cancer Cells through Changes in Mitochondrial and Histone Acetylation.
    Corbet C; Pinto A; Martherus R; Santiago de Jesus JP; Polet F; Feron O
    Cell Metab; 2016 Aug; 24(2):311-23. PubMed ID: 27508876
    [TBL] [Abstract][Full Text] [Related]  

  • 17. 13C isotope-assisted methods for quantifying glutamine metabolism in cancer cells.
    Zhang J; Ahn WS; Gameiro PA; Keibler MA; Zhang Z; Stephanopoulos G
    Methods Enzymol; 2014; 542():369-89. PubMed ID: 24862276
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Acetyl-CoA and acetylcholine metabolism in nerve terminal compartment of thiamine deficient rat brain.
    Jankowska-Kulawy A; Bielarczyk H; Pawełczyk T; Wróblewska M; Szutowicz A
    J Neurochem; 2010 Oct; 115(2):333-42. PubMed ID: 20649840
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Knockdown of both mitochondrial isocitrate dehydrogenase enzymes in pancreatic beta cells inhibits insulin secretion.
    MacDonald MJ; Brown LJ; Longacre MJ; Stoker SW; Kendrick MA; Hasan NM
    Biochim Biophys Acta; 2013 Nov; 1830(11):5104-11. PubMed ID: 23876293
    [TBL] [Abstract][Full Text] [Related]  

  • 20. High extracellular lactate causes reductive carboxylation in breast tissue cell lines grown under normoxic conditions.
    Brodsky AN; Odenwelder DC; Harcum SW
    PLoS One; 2019; 14(6):e0213419. PubMed ID: 31181081
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 23.