106 related articles for article (PubMed ID: 23903227)
1. [Enhancement of quinone hepatotoxicity by cytochrome P450 inhibition].
Ishihara Y
Yakugaku Zasshi; 2013; 133(8):873-8. PubMed ID: 23903227
[TBL] [Abstract][Full Text] [Related]
2. Enhancement of DMNQ-induced hepatocyte toxicity by cytochrome P450 inhibition.
Ishihara Y; Shiba D; Shimamoto N
Toxicol Appl Pharmacol; 2006 Jul; 214(2):109-17. PubMed ID: 16430935
[TBL] [Abstract][Full Text] [Related]
3. Crucial role of cytochrome P450 in hepatotoxicity induced by 2,3-dimethoxy-1,4-naphthoquinone in rats.
Ishihara Y; Ishii S; Sakai Y; Yamamura N; Onishi Y; Shimamoto N
J Appl Toxicol; 2011 Mar; 31(2):173-8. PubMed ID: 20803752
[TBL] [Abstract][Full Text] [Related]
4. Cytotoxicity of RH1 and related aziridinylbenzoquinones: involvement of activation by NAD(P)H:quinone oxidoreductase (NQO1) and oxidative stress.
Nemeikaite-Ceniene A; Sarlauskas J; Anusevicius Z; Nivinskas H; Cenas N
Arch Biochem Biophys; 2003 Aug; 416(1):110-8. PubMed ID: 12859987
[TBL] [Abstract][Full Text] [Related]
5. Cytochrome P450 destruction by benzene metabolites 1,4-benzoquinone and 1,4-hydroquinone and the formation of hydroxyl radicals in minipig liver microsomes.
Kondrová E; Stopka P; Soucek P
Toxicol In Vitro; 2007 Jun; 21(4):566-75. PubMed ID: 17187958
[TBL] [Abstract][Full Text] [Related]
6. Bioactivation of the nontricyclic antidepressant nefazodone to a reactive quinone-imine species in human liver microsomes and recombinant cytochrome P450 3A4.
Kalgutkar AS; Vaz AD; Lame ME; Henne KR; Soglia J; Zhao SX; Abramov YA; Lombardo F; Collin C; Hendsch ZS; Hop CE
Drug Metab Dispos; 2005 Feb; 33(2):243-53. PubMed ID: 15523046
[TBL] [Abstract][Full Text] [Related]
7. Mechanism of arylating quinone toxicity involving Michael adduct formation and induction of endoplasmic reticulum stress.
Wang X; Thomas B; Sachdeva R; Arterburn L; Frye L; Hatcher PG; Cornwell DG; Ma J
Proc Natl Acad Sci U S A; 2006 Mar; 103(10):3604-9. PubMed ID: 16505371
[TBL] [Abstract][Full Text] [Related]
8. One-electron reductive bioactivation of 2,3,5,6-tetramethylbenzoquinone by cytochrome P450.
Goeptar AR; te Koppele JM; van Maanen JM; Zoetemelk CE; Vermeulen NP
Biochem Pharmacol; 1992 Jan; 43(2):343-52. PubMed ID: 1310854
[TBL] [Abstract][Full Text] [Related]
9. Catalysis of the oxidation of steroid and stilbene estrogens to estrogen quinone metabolites by the beta-naphthoflavone-inducible cytochrome P450 IA family.
Roy D; Bernhardt A; Strobel HW; Liehr JG
Arch Biochem Biophys; 1992 Aug; 296(2):450-6. PubMed ID: 1632637
[TBL] [Abstract][Full Text] [Related]
10. Enalapril hepatotoxicity in the rat. Effects of modulators of cytochrome P450 and glutathione.
Jurima-Romet M; Huang HS
Biochem Pharmacol; 1992 Nov; 44(9):1803-10. PubMed ID: 1449535
[TBL] [Abstract][Full Text] [Related]
11. Role of CYP3A and CYP2E1 in alcohol-mediated increases in acetaminophen hepatotoxicity: comparison of wild-type and Cyp2e1(-/-) mice.
Wolf KK; Wood SG; Allard JL; Hunt JA; Gorman N; Walton-Strong BW; Szakacs JG; Duan SX; Hao Q; Court MH; von Moltke LL; Greenblatt DJ; Kostrubsky V; Jeffery EH; Wrighton SA; Gonzalez FJ; Sinclair PR; Sinclair JF
Drug Metab Dispos; 2007 Jul; 35(7):1223-31. PubMed ID: 17392391
[TBL] [Abstract][Full Text] [Related]
12. Contribution of reductase activity to quinone toxicity in three kinds of hepatic cells.
Ishihara Y; Tsuji K; Ishii S; Kashiwagi K; Shimamoto N
Biol Pharm Bull; 2012; 35(4):634-8. PubMed ID: 22466573
[TBL] [Abstract][Full Text] [Related]
13. Mechanism-based inhibition of CYP450: an indicator of drug-induced hepatotoxicity.
Feng S; He X
Curr Drug Metab; 2013 Nov; 14(9):921-45. PubMed ID: 24016115
[TBL] [Abstract][Full Text] [Related]
14. Bioactivation of sitaxentan in liver microsomes, hepatocytes, and expressed human P450s with characterization of the glutathione conjugate by liquid chromatography tandem mass spectrometry.
Erve JC; Gauby S; Maynard JW; Svensson MA; Tonn G; Quinn KP
Chem Res Toxicol; 2013 Jun; 26(6):926-36. PubMed ID: 23721565
[TBL] [Abstract][Full Text] [Related]
15. In vitro evaluation of hepatotoxic drugs in human hepatocytes from multiple donors: Identification of P450 activity as a potential risk factor for drug-induced liver injuries.
Utkarsh D; Loretz C; Li AP
Chem Biol Interact; 2016 Aug; 255():12-22. PubMed ID: 26718876
[TBL] [Abstract][Full Text] [Related]
16. Chimeric mice with humanized liver.
Katoh M; Tateno C; Yoshizato K; Yokoi T
Toxicology; 2008 Apr; 246(1):9-17. PubMed ID: 18248870
[TBL] [Abstract][Full Text] [Related]
17. Interconversion of NAD(H) to NADP(H). A cellular response to quinone-induced oxidative stress in isolated hepatocytes.
Stubberfield CR; Cohen GM
Biochem Pharmacol; 1989 Aug; 38(16):2631-7. PubMed ID: 2764986
[TBL] [Abstract][Full Text] [Related]
18. Characterization of cytochrome P450 isoforms involved in sequential two-step bioactivation of diclofenac to reactive p-benzoquinone imines.
den Braver MW; den Braver-Sewradj SP; Vermeulen NP; Commandeur JN
Toxicol Lett; 2016 Jun; 253():46-54. PubMed ID: 27130197
[TBL] [Abstract][Full Text] [Related]
19. Molecular mechanisms of tirapazamine (SR 4233, Win 59075)-induced hepatocyte toxicity under low oxygen concentrations.
Khan S; O'Brien PJ
Br J Cancer; 1995 Apr; 71(4):780-5. PubMed ID: 7710944
[TBL] [Abstract][Full Text] [Related]
20. Molecular mechanism for alkyl sulfide-modulated carbon tetrachloride-induced hepatotoxicity: the role of cytochrome P450 2E1, P450 2B and glutathione S-transferase expression.
Kim SG; Chung HC; Cho JY
J Pharmacol Exp Ther; 1996 May; 277(2):1058-66. PubMed ID: 8627517
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]