BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

92 related articles for article (PubMed ID: 2391687)

  • 1. Hydroxyperfluoroazobenzenes: novel inhibitors of enzymes of androgen biosynthesis.
    Jarman M; Barrie SE; Deadman JJ; Houghton J; McCague R; Rowlands MG
    J Med Chem; 1990 Sep; 33(9):2452-5. PubMed ID: 2391687
    [TBL] [Abstract][Full Text] [Related]  

  • 2. 4-pregnene-3-one-20 beta-carboxaldehyde: a potent inhibitor of 17 alpha-hydroxylase/C17,20-lyase and of 5 alpha-reductase.
    Li J; Li Y; Son C; Banks P; Brodie A
    J Steroid Biochem Mol Biol; 1992 May; 42(3-4):313-20. PubMed ID: 1606043
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Inhibition of 17 alpha-hydroxylase/C17-C20 lyase by bifluranol and its analogues.
    Barrie SE; Rowlands MG; Foster AB; Jarman M
    J Steroid Biochem; 1989 Dec; 33(6):1191-5. PubMed ID: 2559252
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Esters of 3-pyridylacetic acid that combine potent inhibition of 17 alpha-hydroxylase/C17,20-lyase (cytochrome P45017 alpha) with resistance to esterase hydrolysis.
    Rowlands MG; Barrie SE; Chan F; Houghton J; Jarman M; McCague R; Potter GA
    J Med Chem; 1995 Oct; 38(21):4191-7. PubMed ID: 7473546
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Synthesis and evaluation of novel steroidal oxime inhibitors of P450 17 (17 alpha-hydroxylase/C17-20-lyase) and 5 alpha-reductase types 1 and 2.
    Hartmann RW; Hector M; Haidar S; Ehmer PB; Reichert W; Jose J
    J Med Chem; 2000 Nov; 43(22):4266-77. PubMed ID: 11063622
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Pyridyl substituted benzocycloalkenes: new inhibitors of 17 alpha-hydroxylase/17,20-lyase (P450 17 alpha).
    Sergejew T; Hartmann RW
    J Enzyme Inhib; 1994; 8(2):113-22. PubMed ID: 7539071
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Novel 17-azolyl steroids, potent inhibitors of human cytochrome 17 alpha-hydroxylase-C17,20-lyase (P450(17) alpha): potential agents for the treatment of prostate cancer.
    Njar VC; Kato K; Nnane IP; Grigoryev DN; Long BJ; Brodie AM
    J Med Chem; 1998 Mar; 41(6):902-12. PubMed ID: 9526564
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Inhibition of androgen synthesis in human testicular and prostatic microsomes and in male rats by novel steroidal compounds.
    Nnane IP; Kato K; Liu Y; Long BJ; Lu Q; Wang X; Ling YZ; Brodie A
    Endocrinology; 1999 Jun; 140(6):2891-7. PubMed ID: 10342882
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Inhibition of testicular microsomal cytochrome P-450 (17 alpha-hydroxylase/C-17,20-lyase) by estrogens.
    Onoda M; Hall PF
    Endocrinology; 1981 Sep; 109(3):763-7. PubMed ID: 6973463
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Anti-tumour effects and pharmacokinetic profile of 17-(5'-isoxazolyl)androsta-4,16-dien-3-one (L-39) in mice: an inhibitor of androgen synthesis.
    Nnane IP; Long BJ; Ling YZ; Grigoryev DN; Brodie AM
    Br J Cancer; 2000 Jul; 83(1):74-82. PubMed ID: 10883671
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Effects of some novel inhibitors of C17,20-lyase and 5alpha-reductase in vitro and in vivo and their potential role in the treatment of prostate cancer.
    Nnane IP; Kato K; Liu Y; Lu Q; Wang X; Ling YZ; Brodie A
    Cancer Res; 1998 Sep; 58(17):3826-32. PubMed ID: 9731491
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Novel steroidal inhibitors of human cytochrome P45017 alpha (17 alpha-hydroxylase-C17,20-lyase): potential agents for the treatment of prostatic cancer.
    Potter GA; Barrie SE; Jarman M; Rowlands MG
    J Med Chem; 1995 Jun; 38(13):2463-71. PubMed ID: 7608911
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Antiandrogenic effects of novel androgen synthesis inhibitors on hormone-dependent prostate cancer.
    Long BJ; Grigoryev DN; Nnane IP; Liu Y; Ling YZ; Brodie AM
    Cancer Res; 2000 Dec; 60(23):6630-40. PubMed ID: 11118046
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Growth inhibition of human prostate cells in vitro by novel inhibitors of androgen synthesis.
    Klus GT; Nakamura J; Li JS; Ling YZ; Son C; Kemppainen JA; Wilson EM; Brodie AM
    Cancer Res; 1996 Nov; 56(21):4956-64. PubMed ID: 8895750
    [TBL] [Abstract][Full Text] [Related]  

  • 15. C16 and C17 substituted derivatives of pregnenolone and progesterone as inhibitors of 17alpha-hydroxylase-C17, 20-lyase: synthesis and biological evaluation.
    Haidar S; Hartmann RW
    Arch Pharm (Weinheim); 2002; 335(11-12):526-34. PubMed ID: 12596217
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Synthesis and in vitro activity of some epimeric 20 alpha-hydroxy, 20-oxime and aziridine pregnene derivatives as inhibitors of human 17 alpha-hydroxylase/C17,20-lyase and 5 alpha-reductase.
    Ling YZ; Li JS; Kato K; Liu Y; Wang X; Klus GT; Marat K; Nnane IP; Brodie AM
    Bioorg Med Chem; 1998 Oct; 6(10):1683-93. PubMed ID: 9839000
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Imidazole substituted biphenyls: a new class of highly potent and in vivo active inhibitors of P450 17 as potential therapeutics for treatment of prostate cancer.
    Wachall BG; Hector M; Zhuang Y; Hartmann RW
    Bioorg Med Chem; 1999 Sep; 7(9):1913-24. PubMed ID: 10530940
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Microsomal cytochrome P-450 from neonatal pig testis: two enzymatic activities (17 alpha-hydroxylase and c17,20-lyase) associated with one protein.
    Nakajin S; Shively JE; Yuan PM; Hall PF
    Biochemistry; 1981 Jul; 20(14):4037-42. PubMed ID: 6793062
    [TBL] [Abstract][Full Text] [Related]  

  • 19. 17 beta-(cyclopropylamino)-androst-5-en-3 beta-ol, a selective mechanism-based inhibitor of cytochrome P450(17 alpha) (steroid 17 alpha-hydroxylase/C17-20 lyase).
    Angelastro MR; Laughlin ME; Schatzman GL; Bey P; Blohm TR
    Biochem Biophys Res Commun; 1989 Aug; 162(3):1571-7. PubMed ID: 2788415
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Determination of 17α-hydroxylase-C17,20-lyase (P45017α) enzyme activities and their inhibition by selected steroidal picolyl and picolinylidene compounds.
    Szabó N; Ajduković JJ; Djurendić EA; Sakač MN; Ignáth I; Gardi J; Mahmoud G; Klisurić OR; Jovanović-Šanta S; Penov Gaši KM; Szécsi M
    Acta Biol Hung; 2015 Mar; 66(1):41-51. PubMed ID: 25740437
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 5.