179 related articles for article (PubMed ID: 23919527)
1. Designing CXCL8-based decoy proteins with strong anti-inflammatory activity in vivo.
Falsone A; Wabitsch V; Geretti E; Potzinger H; Gerlza T; Robinson J; Adage T; Teixeira MM; Kungl AJ
Biosci Rep; 2013 Sep; 33(5):. PubMed ID: 23919527
[TBL] [Abstract][Full Text] [Related]
2. Probing the role of CXC motif in chemokine CXCL8 for high affinity binding and activation of CXCR1 and CXCR2 receptors.
Joseph PR; Sarmiento JM; Mishra AK; Das ST; Garofalo RP; Navarro J; Rajarathnam K
J Biol Chem; 2010 Sep; 285(38):29262-9. PubMed ID: 20630874
[TBL] [Abstract][Full Text] [Related]
3. PA401, a novel CXCL8-based biologic therapeutic with increased glycosaminoglycan binding, reduces bronchoalveolar lavage neutrophils and systemic inflammatory markers in a murine model of LPS-induced lung inflammation.
Adage T; Del Bene F; Fiorentini F; Doornbos RP; Zankl C; Bartley MR; Kungl AJ
Cytokine; 2015 Dec; 76(2):433-441. PubMed ID: 26303011
[TBL] [Abstract][Full Text] [Related]
4. Fine-Tuning of GPCR-Chemokine Interactions. Design and Identification of Chemokine Analogues as Receptor Agonists, Biased Agonists, and Antagonists.
Navarro J
Biochemistry; 2019 Mar; 58(10):1432-1439. PubMed ID: 30726064
[TBL] [Abstract][Full Text] [Related]
5. A combinatorial approach to biophysically characterise chemokine-glycan binding affinities for drug development.
Gerlza T; Hecher B; Jeremic D; Fuchs T; Gschwandtner M; Falsone A; Gesslbauer B; Kungl AJ
Molecules; 2014 Jul; 19(7):10618-34. PubMed ID: 25054442
[TBL] [Abstract][Full Text] [Related]
6. Dynamics-Derived Insights into Complex Formation between the CXCL8 Monomer and CXCR1 N-Terminal Domain: An NMR Study.
Joseph PRB; Spyracopoulos L; Rajarathnam K
Molecules; 2018 Oct; 23(11):. PubMed ID: 30384436
[TBL] [Abstract][Full Text] [Related]
7. Glycosaminoglycans are important mediators of neutrophilic inflammation in vivo.
Gschwandtner M; Strutzmann E; Teixeira MM; Anders HJ; Diedrichs-Möhring M; Gerlza T; Wildner G; Russo RC; Adage T; Kungl AJ
Cytokine; 2017 Mar; 91():65-73. PubMed ID: 28011398
[TBL] [Abstract][Full Text] [Related]
8. Heparin-bound chemokine CXCL8 monomer and dimer are impaired for CXCR1 and CXCR2 activation: implications for gradients and neutrophil trafficking.
Joseph PRB; Sawant KV; Rajarathnam K
Open Biol; 2017 Nov; 7(11):. PubMed ID: 29118271
[TBL] [Abstract][Full Text] [Related]
9. Solution NMR characterization of WT CXCL8 monomer and dimer binding to CXCR1 N-terminal domain.
Joseph PR; Rajarathnam K
Protein Sci; 2015 Jan; 24(1):81-92. PubMed ID: 25327289
[TBL] [Abstract][Full Text] [Related]
10. Differential activation and regulation of CXCR1 and CXCR2 by CXCL8 monomer and dimer.
Nasser MW; Raghuwanshi SK; Grant DJ; Jala VR; Rajarathnam K; Richardson RM
J Immunol; 2009 Sep; 183(5):3425-32. PubMed ID: 19667085
[TBL] [Abstract][Full Text] [Related]
11. Effects of K11R and G31P Mutations on the Structure and Biological Activities of CXCL8: Solution Structure of Human CXCL8
Cheng HT; Yu HY; Gordon JR; Li F; Cheng JW
Molecules; 2017 Jul; 22(7):. PubMed ID: 28754019
[TBL] [Abstract][Full Text] [Related]
12. CXCL8((3-73))K11R/G31P antagonizes ligand binding to the neutrophil CXCR1 and CXCR2 receptors and cellular responses to CXCL8/IL-8.
Li F; Zhang X; Gordon JR
Biochem Biophys Res Commun; 2002 May; 293(3):939-44. PubMed ID: 12051749
[TBL] [Abstract][Full Text] [Related]
13. The dynamics of interleukin-8 and its interaction with human CXC receptor I peptide.
Kendrick AA; Holliday MJ; Isern NG; Zhang F; Camilloni C; Huynh C; Vendruscolo M; Armstrong G; Eisenmesser EZ
Protein Sci; 2014 Apr; 23(4):464-80. PubMed ID: 24442768
[TBL] [Abstract][Full Text] [Related]
14. Combined anti CXC receptors 1 and 2 therapy is a promising anti-inflammatory treatment for respiratory diseases by reducing neutrophil migration and activation.
Planagumà A; Domènech T; Pont M; Calama E; García-González V; López R; Aulí M; López M; Fonquerna S; Ramos I; de Alba J; Nueda A; Prats N; Segarra V; Miralpeix M; Lehner MD
Pulm Pharmacol Ther; 2015 Oct; 34():37-45. PubMed ID: 26271598
[TBL] [Abstract][Full Text] [Related]
15. Truncation of CXCL8 to CXCL8(9-77) enhances actin polymerization and in vivo migration of neutrophils.
Metzemaekers M; Vandendriessche S; Berghmans N; Gouwy M; Proost P
J Leukoc Biol; 2020 Jun; 107(6):1167-1173. PubMed ID: 32272490
[TBL] [Abstract][Full Text] [Related]
16. The chemokine receptors CXCR1 and CXCR2 couple to distinct G protein-coupled receptor kinases to mediate and regulate leukocyte functions.
Raghuwanshi SK; Su Y; Singh V; Haynes K; Richmond A; Richardson RM
J Immunol; 2012 Sep; 189(6):2824-32. PubMed ID: 22869904
[TBL] [Abstract][Full Text] [Related]
17. Novel Anti-Inflammatory Peptides Based on Chemokine-Glycosaminoglycan Interactions Reduce Leukocyte Migration and Disease Severity in a Model of Rheumatoid Arthritis.
McNaughton EF; Eustace AD; King S; Sessions RB; Kay A; Farris M; Broadbridge R; Kehoe O; Kungl AJ; Middleton J
J Immunol; 2018 May; 200(9):3201-3217. PubMed ID: 29572348
[TBL] [Abstract][Full Text] [Related]
18. Glycosaminoglycan-Mediated Downstream Signaling of CXCL8 Binding to Endothelial Cells.
Derler R; Gesslbauer B; Weber C; Strutzmann E; Miller I; Kungl A
Int J Mol Sci; 2017 Dec; 18(12):. PubMed ID: 29207576
[TBL] [Abstract][Full Text] [Related]
19. Synergistic interactions between chemokine receptor elements in recognition of interleukin-8 by soluble receptor mimics.
Barter EF; Stone MJ
Biochemistry; 2012 Feb; 51(6):1322-31. PubMed ID: 22242662
[TBL] [Abstract][Full Text] [Related]
20. Potentiation of inflammatory CXCL8 signalling sustains cell survival in PTEN-deficient prostate carcinoma.
Maxwell PJ; Coulter J; Walker SM; McKechnie M; Neisen J; McCabe N; Kennedy RD; Salto-Tellez M; Albanese C; Waugh DJ
Eur Urol; 2013 Aug; 64(2):177-88. PubMed ID: 22939387
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]