These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
3. Synthesis and biological evaluation of picolinamides and thiazole-2-carboxamides as mGluR5 (metabotropic glutamate receptor 5) antagonists. Vu HN; Kim JY; Hassan AH; Choi K; Park JH; Park KD; Lee JK; Pae AN; Choo H; Min SJ; Cho YS Bioorg Med Chem Lett; 2016 Jan; 26(1):140-4. PubMed ID: 26598462 [TBL] [Abstract][Full Text] [Related]
4. Discovery and structure-activity relationship of 1,3-cyclohexyl amide derivatives as novel mGluR5 negative allosteric modulators. Zhou H; Topiol SW; Grenon M; Jimenez HN; Uberti MA; Smith DG; Brodbeck RM; Chandrasena G; Pedersen H; Madsen JC; Doller D; Li G Bioorg Med Chem Lett; 2013 Mar; 23(5):1398-406. PubMed ID: 23357634 [TBL] [Abstract][Full Text] [Related]
5. Magnetic resonance and optical imaging probes for NMDA receptors on the cell surface of neurons: synthesis and evaluation in cellulo. Sim N; Pal R; Parker D; Engelmann J; Mishra A; Gottschalk S Org Biomol Chem; 2014 Dec; 12(46):9389-404. PubMed ID: 25317742 [TBL] [Abstract][Full Text] [Related]
6. Brain tumor enhancement in magnetic resonance imaging at 3 tesla: intraindividual comparison of two high relaxivity macromolecular contrast media with a standard extracellular gd-chelate in a rat brain tumor model. Fries P; Runge VM; Bücker A; Schürholz H; Reith W; Robert P; Jackson C; Lanz T; Schneider G Invest Radiol; 2009 Apr; 44(4):200-6. PubMed ID: 19300099 [TBL] [Abstract][Full Text] [Related]
7. A molecular receptor targeted, hydroxyapatite nanocrystal based multi-modal contrast agent. Ashokan A; Menon D; Nair S; Koyakutty M Biomaterials; 2010 Mar; 31(9):2606-16. PubMed ID: 20035998 [TBL] [Abstract][Full Text] [Related]
8. Allosteric potentiators of metabotropic glutamate receptor subtype 5 have differential effects on different signaling pathways in cortical astrocytes. Zhang Y; Rodriguez AL; Conn PJ J Pharmacol Exp Ther; 2005 Dec; 315(3):1212-9. PubMed ID: 16135701 [TBL] [Abstract][Full Text] [Related]
9. A novel selective positive allosteric modulator of metabotropic glutamate receptor subtype 5 has in vivo activity and antipsychotic-like effects in rat behavioral models. Kinney GG; O'Brien JA; Lemaire W; Burno M; Bickel DJ; Clements MK; Chen TB; Wisnoski DD; Lindsley CW; Tiller PR; Smith S; Jacobson MA; Sur C; Duggan ME; Pettibone DJ; Conn PJ; Williams DL J Pharmacol Exp Ther; 2005 Apr; 313(1):199-206. PubMed ID: 15608073 [TBL] [Abstract][Full Text] [Related]
10. Scaffold hopping approach towards various AFQ-056 analogs as potent metabotropic glutamate receptor 5 negative allosteric modulators. Kubas H; Meyer U; Hechenberger M; Klein KU; Plitt P; Zemribo R; Spexgoor HW; van Assema SG; Abel U Bioorg Med Chem Lett; 2013 Dec; 23(23):6370-6. PubMed ID: 24125886 [TBL] [Abstract][Full Text] [Related]
11. Microscopic visualization of metabotropic glutamate receptors on the surface of living cells using bifunctional magnetic resonance imaging probes. Mishra A; Mishra R; Gottschalk S; Pal R; Sim N; Engelmann J; Goldberg M; Parker D ACS Chem Neurosci; 2014 Feb; 5(2):128-37. PubMed ID: 24251400 [TBL] [Abstract][Full Text] [Related]
12. A new class of Gd-based DO3A-ethylamine-derived targeted contrast agents for MR and optical imaging. Mishra A; Pfeuffer J; Mishra R; Engelmann J; Mishra AK; Ugurbil K; Logothetis NK Bioconjug Chem; 2006; 17(3):773-80. PubMed ID: 16704217 [TBL] [Abstract][Full Text] [Related]
14. Synthesis and relaxometric characterization of a MRI Gd-based probe responsive to glutamic acid decarboxylase enzymatic activity. Napolitano R; Pariani G; Fedeli F; Baranyai Z; Aswendt M; Aime S; Gianolio E J Med Chem; 2013 Mar; 56(6):2466-77. PubMed ID: 23469759 [TBL] [Abstract][Full Text] [Related]
15. Discovery of biological evaluation of pyrazole/imidazole amides as mGlu5 receptor negative allosteric modulators. Chae E; Shin YJ; Ryu EJ; Ji MK; Ryune Cho N; Lee KH; Jeong HJ; Kim SJ; Choi Y; Seok Oh K; Park CE; Soo Yoon Y Bioorg Med Chem Lett; 2013 Apr; 23(7):2134-9. PubMed ID: 23434029 [TBL] [Abstract][Full Text] [Related]
16. Pushing the sensitivity envelope of lanthanide-based magnetic resonance imaging (MRI) contrast agents for molecular imaging applications. Aime S; Castelli DD; Crich SG; Gianolio E; Terreno E Acc Chem Res; 2009 Jul; 42(7):822-31. PubMed ID: 19534516 [TBL] [Abstract][Full Text] [Related]
17. Metabotropic glutamate receptor mGluR5 subcellular distribution and developmental expression in hypothalamus. van den Pol AN; Romano C; Ghosh P J Comp Neurol; 1995 Nov; 362(1):134-50. PubMed ID: 8576426 [TBL] [Abstract][Full Text] [Related]
18. MRI probes for sensing biologically relevant metal ions. Bonnet CS; Tóth E Future Med Chem; 2010 Mar; 2(3):367-84. PubMed ID: 21426172 [TBL] [Abstract][Full Text] [Related]
19. In vitro and in vivo evaluation of [18F]-FDEGPECO as a PET tracer for imaging the metabotropic glutamate receptor subtype 5 (mGluR5). Wanger-Baumann CA; Mu L; Honer M; Belli S; Alf MF; Schubiger PA; Krämer SD; Ametamey SM Neuroimage; 2011 Jun; 56(3):984-91. PubMed ID: 21406237 [TBL] [Abstract][Full Text] [Related]
20. Lanthanide(III) complexes that contain a self-immolative arm: potential enzyme responsive contrast agents for magnetic resonance imaging. Chauvin T; Torres S; Rosseto R; Kotek J; Badet B; Durand P; Tóth E Chemistry; 2012 Jan; 18(5):1408-18. PubMed ID: 22213022 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]