672 related articles for article (PubMed ID: 23928304)
1. Autoregulation of the mechanistic target of rapamycin (mTOR) complex 2 integrity is controlled by an ATP-dependent mechanism.
Chen CH; Kiyan V; Zhylkibayev AA; Kazyken D; Bulgakova O; Page KE; Bersimbaev RI; Spooner E; Sarbassov DD
J Biol Chem; 2013 Sep; 288(38):27019-27030. PubMed ID: 23928304
[TBL] [Abstract][Full Text] [Related]
2. PRR5, a novel component of mTOR complex 2, regulates platelet-derived growth factor receptor beta expression and signaling.
Woo SY; Kim DH; Jun CB; Kim YM; Haar EV; Lee SI; Hegg JW; Bandhakavi S; Griffin TJ; Kim DH
J Biol Chem; 2007 Aug; 282(35):25604-12. PubMed ID: 17599906
[TBL] [Abstract][Full Text] [Related]
3. The mTOR (mammalian target of rapamycin) kinase maintains integrity of mTOR complex 2.
Chen CH; Sarbassov dos D
J Biol Chem; 2011 Nov; 286(46):40386-94. PubMed ID: 21965657
[TBL] [Abstract][Full Text] [Related]
4. Sin1 phosphorylation impairs mTORC2 complex integrity and inhibits downstream Akt signalling to suppress tumorigenesis.
Liu P; Gan W; Inuzuka H; Lazorchak AS; Gao D; Arojo O; Liu D; Wan L; Zhai B; Yu Y; Yuan M; Kim BM; Shaik S; Menon S; Gygi SP; Lee TH; Asara JM; Manning BD; Blenis J; Su B; Wei W
Nat Cell Biol; 2013 Nov; 15(11):1340-50. PubMed ID: 24161930
[TBL] [Abstract][Full Text] [Related]
5. A Positive Feedback Loop between Akt and mTORC2 via SIN1 Phosphorylation.
Yang G; Murashige DS; Humphrey SJ; James DE
Cell Rep; 2015 Aug; 12(6):937-43. PubMed ID: 26235620
[TBL] [Abstract][Full Text] [Related]
6. Crosstalk between mTOR complexes.
Xie J; Proud CG
Nat Cell Biol; 2013 Nov; 15(11):1263-5. PubMed ID: 24189516
[TBL] [Abstract][Full Text] [Related]
7. Hydrophobic motif site-phosphorylated protein kinase CβII between mTORC2 and Akt regulates high glucose-induced mesangial cell hypertrophy.
Das F; Ghosh-Choudhury N; Mariappan MM; Kasinath BS; Choudhury GG
Am J Physiol Cell Physiol; 2016 Apr; 310(7):C583-96. PubMed ID: 26739493
[TBL] [Abstract][Full Text] [Related]
8. Dual phosphorylation of Sin1 at T86 and T398 negatively regulates mTORC2 complex integrity and activity.
Liu P; Guo J; Gan W; Wei W
Protein Cell; 2014 Mar; 5(3):171-7. PubMed ID: 24481632
[TBL] [Abstract][Full Text] [Related]
9. mTOR complex 2 (mTORC2) controls hydrophobic motif phosphorylation and activation of serum- and glucocorticoid-induced protein kinase 1 (SGK1).
García-Martínez JM; Alessi DR
Biochem J; 2008 Dec; 416(3):375-85. PubMed ID: 18925875
[TBL] [Abstract][Full Text] [Related]
10. Receptor-recognized α₂-macroglobulin binds to cell surface-associated GRP78 and activates mTORC1 and mTORC2 signaling in prostate cancer cells.
Misra UK; Pizzo SV
PLoS One; 2012; 7(12):e51735. PubMed ID: 23272152
[TBL] [Abstract][Full Text] [Related]
11. TRAF2 and OTUD7B govern a ubiquitin-dependent switch that regulates mTORC2 signalling.
Wang B; Jie Z; Joo D; Ordureau A; Liu P; Gan W; Guo J; Zhang J; North BJ; Dai X; Cheng X; Bian X; Zhang L; Harper JW; Sun SC; Wei W
Nature; 2017 May; 545(7654):365-369. PubMed ID: 28489822
[TBL] [Abstract][Full Text] [Related]
12. Cystine Induced-mTORC2 Activation through Promoting Sin1 Phosphorylation to Suppress Cancer Cell Ferroptosis.
Wang G; Chen L; Qin S; Zheng Y; Xia C; Yao J; Wang P; Deng L
Mol Nutr Food Res; 2022 Dec; 66(23):e2200186. PubMed ID: 36189894
[TBL] [Abstract][Full Text] [Related]
13. mTOR has a developmental stage-specific role in mitochondrial fitness independent of conventional mTORC1 and mTORC2 and the kinase activity.
Kalim KW; Zhang S; Chen X; Li Y; Yang JQ; Zheng Y; Guo F
PLoS One; 2017; 12(8):e0183266. PubMed ID: 28813526
[TBL] [Abstract][Full Text] [Related]
14. Distinct signaling mechanisms of mTORC1 and mTORC2 in glioblastoma multiforme: a tale of two complexes.
Jhanwar-Uniyal M; Gillick JL; Neil J; Tobias M; Thwing ZE; Murali R
Adv Biol Regul; 2015 Jan; 57():64-74. PubMed ID: 25442674
[TBL] [Abstract][Full Text] [Related]
15. PtdIns(3,4,5)P3-Dependent Activation of the mTORC2 Kinase Complex.
Liu P; Gan W; Chin YR; Ogura K; Guo J; Zhang J; Wang B; Blenis J; Cantley LC; Toker A; Su B; Wei W
Cancer Discov; 2015 Nov; 5(11):1194-209. PubMed ID: 26293922
[TBL] [Abstract][Full Text] [Related]
16. mTORC1-activated S6K1 phosphorylates Rictor on threonine 1135 and regulates mTORC2 signaling.
Julien LA; Carriere A; Moreau J; Roux PP
Mol Cell Biol; 2010 Feb; 30(4):908-21. PubMed ID: 19995915
[TBL] [Abstract][Full Text] [Related]
17. mTORC1 and mTORC2 regulate insulin secretion through Akt in INS-1 cells.
Le Bacquer O; Queniat G; Gmyr V; Kerr-Conte J; Lefebvre B; Pattou F
J Endocrinol; 2013 Jan; 216(1):21-9. PubMed ID: 23092880
[TBL] [Abstract][Full Text] [Related]
18. DNA-dependent protein kinase catalytic subunit (DNA-PKcs)-SIN1 association mediates ultraviolet B (UVB)-induced Akt Ser-473 phosphorylation and skin cell survival.
Tu Y; Ji C; Yang B; Yang Z; Gu H; Lu CC; Wang R; Su ZL; Chen B; Sun WL; Xia JP; Bi ZG; He L
Mol Cancer; 2013 Dec; 12(1):172. PubMed ID: 24365180
[TBL] [Abstract][Full Text] [Related]
19. Diverse signaling mechanisms of mTOR complexes: mTORC1 and mTORC2 in forming a formidable relationship.
Jhanwar-Uniyal M; Wainwright JV; Mohan AL; Tobias ME; Murali R; Gandhi CD; Schmidt MH
Adv Biol Regul; 2019 May; 72():51-62. PubMed ID: 31010692
[TBL] [Abstract][Full Text] [Related]
20. Akt-dependent activation of mTORC1 complex involves phosphorylation of mTOR (mammalian target of rapamycin) by IκB kinase α (IKKα).
Dan HC; Ebbs A; Pasparakis M; Van Dyke T; Basseres DS; Baldwin AS
J Biol Chem; 2014 Sep; 289(36):25227-40. PubMed ID: 24990947
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]