BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

278 related articles for article (PubMed ID: 23936501)

  • 1. Trichothecin induces cell death in NF-κB constitutively activated human cancer cells via inhibition of IKKβ phosphorylation.
    Su J; Zhao P; Kong L; Li X; Yan J; Zeng Y; Li Y
    PLoS One; 2013; 8(8):e71333. PubMed ID: 23936501
    [TBL] [Abstract][Full Text] [Related]  

  • 2. 3-Formylchromone interacts with cysteine 38 in p65 protein and with cysteine 179 in IκBα kinase, leading to down-regulation of nuclear factor-κB (NF-κB)-regulated gene products and sensitization of tumor cells.
    Yadav VR; Prasad S; Gupta SC; Sung B; Phatak SS; Zhang S; Aggarwal BB
    J Biol Chem; 2012 Jan; 287(1):245-256. PubMed ID: 22065587
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Targeting nuclear factor-kappa B activation pathway by thymoquinone: role in suppression of antiapoptotic gene products and enhancement of apoptosis.
    Sethi G; Ahn KS; Aggarwal BB
    Mol Cancer Res; 2008 Jun; 6(6):1059-70. PubMed ID: 18567808
    [TBL] [Abstract][Full Text] [Related]  

  • 4. A synthetic triterpenoid, CDDO-Me, inhibits IkappaBalpha kinase and enhances apoptosis induced by TNF and chemotherapeutic agents through down-regulation of expression of nuclear factor kappaB-regulated gene products in human leukemic cells.
    Shishodia S; Sethi G; Konopleva M; Andreeff M; Aggarwal BB
    Clin Cancer Res; 2006 Mar; 12(6):1828-38. PubMed ID: 16551868
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Suppression of constitutive and tumor necrosis factor alpha-induced nuclear factor (NF)-kappaB activation and induction of apoptosis by apigenin in human prostate carcinoma PC-3 cells: correlation with down-regulation of NF-kappaB-responsive genes.
    Shukla S; Gupta S
    Clin Cancer Res; 2004 May; 10(9):3169-78. PubMed ID: 15131058
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Retigeric acid B exhibits antitumor activity through suppression of nuclear factor-κB signaling in prostate cancer cells in vitro and in vivo.
    Liu YQ; Hu XY; Lu T; Cheng YN; Young CY; Yuan HQ; Lou HX
    PLoS One; 2012; 7(5):e38000. PubMed ID: 22666431
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Honokiol inhibits TNF-alpha-stimulated NF-kappaB activation and NF-kappaB-regulated gene expression through suppression of IKK activation.
    Tse AK; Wan CK; Shen XL; Yang M; Fong WF
    Biochem Pharmacol; 2005 Nov; 70(10):1443-57. PubMed ID: 16181613
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Inhibition of the NEMO/IKKβ association complex formation, a novel mechanism associated with the NF-κB activation suppression by Withania somnifera's key metabolite withaferin A.
    Grover A; Shandilya A; Punetha A; Bisaria VS; Sundar D
    BMC Genomics; 2010 Dec; 11 Suppl 4(Suppl 4):S25. PubMed ID: 21143809
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Pinitol targets nuclear factor-kappaB activation pathway leading to inhibition of gene products associated with proliferation, apoptosis, invasion, and angiogenesis.
    Sethi G; Ahn KS; Sung B; Aggarwal BB
    Mol Cancer Ther; 2008 Jun; 7(6):1604-14. PubMed ID: 18566231
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Coronarin D, a labdane diterpene, inhibits both constitutive and inducible nuclear factor-kappa B pathway activation, leading to potentiation of apoptosis, inhibition of invasion, and suppression of osteoclastogenesis.
    Kunnumakkara AB; Ichikawa H; Anand P; Mohankumar CJ; Hema PS; Nair MS; Aggarwal BB
    Mol Cancer Ther; 2008 Oct; 7(10):3306-17. PubMed ID: 18852134
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Curcumin (diferuloylmethane) inhibits constitutive NF-kappaB activation, induces G1/S arrest, suppresses proliferation, and induces apoptosis in mantle cell lymphoma.
    Shishodia S; Amin HM; Lai R; Aggarwal BB
    Biochem Pharmacol; 2005 Sep; 70(5):700-13. PubMed ID: 16023083
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Fisetin, an inhibitor of cyclin-dependent kinase 6, down-regulates nuclear factor-kappaB-regulated cell proliferation, antiapoptotic and metastatic gene products through the suppression of TAK-1 and receptor-interacting protein-regulated IkappaBalpha kinase activation.
    Sung B; Pandey MK; Aggarwal BB
    Mol Pharmacol; 2007 Jun; 71(6):1703-14. PubMed ID: 17387141
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Differential activity of GSK-3 isoforms regulates NF-κB and TRAIL- or TNFα induced apoptosis in pancreatic cancer cells.
    Zhang JS; Herreros-Villanueva M; Koenig A; Deng Z; de Narvajas AA; Gomez TS; Meng X; Bujanda L; Ellenrieder V; Li XK; Kaufmann SH; Billadeau DD
    Cell Death Dis; 2014 Mar; 5(3):e1142. PubMed ID: 24675460
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Nuclear IKKbeta is an adaptor protein for IkappaBalpha ubiquitination and degradation in UV-induced NF-kappaB activation.
    Tsuchiya Y; Asano T; Nakayama K; Kato T; Karin M; Kamata H
    Mol Cell; 2010 Aug; 39(4):570-82. PubMed ID: 20797629
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Magnolol suppresses NF-kappaB activation and NF-kappaB regulated gene expression through inhibition of IkappaB kinase activation.
    Tse AK; Wan CK; Zhu GY; Shen XL; Cheung HY; Yang M; Fong WF
    Mol Immunol; 2007 Apr; 44(10):2647-58. PubMed ID: 17240450
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Identification of a novel blocker of I kappa B alpha kinase that enhances cellular apoptosis and inhibits cellular invasion through suppression of NF-kappa B-regulated gene products.
    Ichikawa H; Takada Y; Murakami A; Aggarwal BB
    J Immunol; 2005 Jun; 174(11):7383-92. PubMed ID: 15905586
    [TBL] [Abstract][Full Text] [Related]  

  • 17. PMS1077 sensitizes TNF-α induced apoptosis in human prostate cancer cells by blocking NF-κB signaling pathway.
    Shi J; Chen J; Serradji N; Xu X; Zhou H; Ma Y; Sun Z; Jiang P; Du Y; Yang J; Dong C; Wang Q
    PLoS One; 2013; 8(4):e61132. PubMed ID: 23593410
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Digitoflavone inhibits IκBα kinase and enhances apoptosis induced by TNFα through downregulation of expression of nuclear factor κB-regulated gene products in human pancreatic cancer cells.
    Cai X; Lu W; Yang Y; Yang J; Ye J; Gu Z; Hu C; Wang X; Cao P
    PLoS One; 2013; 8(10):e77126. PubMed ID: 24146961
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Cryptopleurine targets NF-κB pathway, leading to inhibition of gene products associated with cell survival, proliferation, invasion, and angiogenesis.
    Jin HR; Jin SZ; Cai XF; Li D; Wu X; Nan JX; Lee JJ; Jin X
    PLoS One; 2012; 7(6):e40355. PubMed ID: 22768286
    [TBL] [Abstract][Full Text] [Related]  

  • 20. N-(4-hydroxyphenyl)retinamide inhibits invasion, suppresses osteoclastogenesis, and potentiates apoptosis through down-regulation of I(kappa)B(alpha) kinase and nuclear factor-kappaB-regulated gene products.
    Shishodia S; Gutierrez AM; Lotan R; Aggarwal BB
    Cancer Res; 2005 Oct; 65(20):9555-65. PubMed ID: 16230421
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.