BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

627 related articles for article (PubMed ID: 23937428)

  • 1. Transforming growth factor-β(1) represses bone morphogenetic protein-mediated Smad signaling in pulmonary artery smooth muscle cells via Smad3.
    Upton PD; Davies RJ; Tajsic T; Morrell NW
    Am J Respir Cell Mol Biol; 2013 Dec; 49(6):1135-45. PubMed ID: 23937428
    [TBL] [Abstract][Full Text] [Related]  

  • 2. BMP type II receptor deficiency confers resistance to growth inhibition by TGF-β in pulmonary artery smooth muscle cells: role of proinflammatory cytokines.
    Davies RJ; Holmes AM; Deighton J; Long L; Yang X; Barker L; Walker C; Budd DC; Upton PD; Morrell NW
    Am J Physiol Lung Cell Mol Physiol; 2012 Mar; 302(6):L604-15. PubMed ID: 22227206
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Inhibition of overactive transforming growth factor-β signaling by prostacyclin analogs in pulmonary arterial hypertension.
    Ogo T; Chowdhury HM; Yang J; Long L; Li X; Torres Cleuren YN; Morrell NW; Schermuly RT; Trembath RC; Nasim MT
    Am J Respir Cell Mol Biol; 2013 Jun; 48(6):733-41. PubMed ID: 23418342
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Sildenafil potentiates bone morphogenetic protein signaling in pulmonary arterial smooth muscle cells and in experimental pulmonary hypertension.
    Yang J; Li X; Al-Lamki RS; Wu C; Weiss A; Berk J; Schermuly RT; Morrell NW
    Arterioscler Thromb Vasc Biol; 2013 Jan; 33(1):34-42. PubMed ID: 23139294
    [TBL] [Abstract][Full Text] [Related]  

  • 5. [Bone morphogenetic protein 4 increases canonical transient receptor potential protein expression by activating bone morphogenetic protein receptor Ⅱ/Smad signaling pathways in pulmonary arterial smooth muscle cells].
    Li XY; Ran PX; Wang J
    Zhonghua Jie He He Hu Xi Za Zhi; 2016 Jul; 39(7):539-45. PubMed ID: 27430926
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Smad-dependent and smad-independent induction of id1 by prostacyclin analogues inhibits proliferation of pulmonary artery smooth muscle cells in vitro and in vivo.
    Yang J; Li X; Al-Lamki RS; Southwood M; Zhao J; Lever AM; Grimminger F; Schermuly RT; Morrell NW
    Circ Res; 2010 Jul; 107(2):252-62. PubMed ID: 20522807
    [TBL] [Abstract][Full Text] [Related]  

  • 7. BMP4 inhibits PDGF-induced proliferation and collagen synthesis via PKA-mediated inhibition of calpain-2 in pulmonary artery smooth muscle cells.
    Cai P; Kovacs L; Dong S; Wu G; Su Y
    Am J Physiol Lung Cell Mol Physiol; 2017 May; 312(5):L638-L648. PubMed ID: 28235949
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Id proteins are critical downstream effectors of BMP signaling in human pulmonary arterial smooth muscle cells.
    Yang J; Li X; Li Y; Southwood M; Ye L; Long L; Al-Lamki RS; Morrell NW
    Am J Physiol Lung Cell Mol Physiol; 2013 Aug; 305(4):L312-21. PubMed ID: 23771884
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Altered bone morphogenetic protein and transforming growth factor-beta signaling in rat models of pulmonary hypertension: potential for activin receptor-like kinase-5 inhibition in prevention and progression of disease.
    Long L; Crosby A; Yang X; Southwood M; Upton PD; Kim DK; Morrell NW
    Circulation; 2009 Feb; 119(4):566-76. PubMed ID: 19153267
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Growth differentiation factor-9 signaling is mediated by the type I receptor, activin receptor-like kinase 5.
    Mazerbourg S; Klein C; Roh J; Kaivo-Oja N; Mottershead DG; Korchynskyi O; Ritvos O; Hsueh AJ
    Mol Endocrinol; 2004 Mar; 18(3):653-65. PubMed ID: 14684852
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Altered growth responses of pulmonary artery smooth muscle cells from patients with primary pulmonary hypertension to transforming growth factor-beta(1) and bone morphogenetic proteins.
    Morrell NW; Yang X; Upton PD; Jourdan KB; Morgan N; Sheares KK; Trembath RC
    Circulation; 2001 Aug; 104(7):790-5. PubMed ID: 11502704
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Involvement of the bone morphogenetic protein system in endothelin- and aldosterone-induced cell proliferation of pulmonary arterial smooth muscle cells isolated from human patients with pulmonary arterial hypertension.
    Yamanaka R; Otsuka F; Nakamura K; Yamashita M; Otani H; Takeda M; Matsumoto Y; Kusano KF; Ito H; Makino H
    Hypertens Res; 2010 May; 33(5):435-45. PubMed ID: 20186146
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Activin-like kinase 5 (ALK5) mediates abnormal proliferation of vascular smooth muscle cells from patients with familial pulmonary arterial hypertension and is involved in the progression of experimental pulmonary arterial hypertension induced by monocrotaline.
    Thomas M; Docx C; Holmes AM; Beach S; Duggan N; England K; Leblanc C; Lebret C; Schindler F; Raza F; Walker C; Crosby A; Davies RJ; Morrell NW; Budd DC
    Am J Pathol; 2009 Feb; 174(2):380-9. PubMed ID: 19116361
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Hypoxia induces downregulation of PPAR-γ in isolated pulmonary arterial smooth muscle cells and in rat lung via transforming growth factor-β signaling.
    Gong K; Xing D; Li P; Aksut B; Ambalavanan N; Yang Q; Nozell SE; Oparil S; Chen YF
    Am J Physiol Lung Cell Mol Physiol; 2011 Dec; 301(6):L899-907. PubMed ID: 21926264
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Codependence of Bone Morphogenetic Protein Receptor 2 and Transforming Growth Factor-β in Elastic Fiber Assembly and Its Perturbation in Pulmonary Arterial Hypertension.
    Tojais NF; Cao A; Lai YJ; Wang L; Chen PI; Alcazar MAA; de Jesus Perez VA; Hopper RK; Rhodes CJ; Bill MA; Sakai LY; Rabinovitch M
    Arterioscler Thromb Vasc Biol; 2017 Aug; 37(8):1559-1569. PubMed ID: 28619995
    [TBL] [Abstract][Full Text] [Related]  

  • 16. ANP signaling inhibits TGF-beta-induced Smad2 and Smad3 nuclear translocation and extracellular matrix expression in rat pulmonary arterial smooth muscle cells.
    Li P; Oparil S; Novak L; Cao X; Shi W; Lucas J; Chen YF
    J Appl Physiol (1985); 2007 Jan; 102(1):390-8. PubMed ID: 17038494
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Bone morphogenetic protein signalling in heritable versus idiopathic pulmonary hypertension.
    Dewachter L; Adnot S; Guignabert C; Tu L; Marcos E; Fadel E; Humbert M; Dartevelle P; Simonneau G; Naeije R; Eddahibi S
    Eur Respir J; 2009 Nov; 34(5):1100-10. PubMed ID: 19324947
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Mutations in bone morphogenetic protein type II receptor cause dysregulation of Id gene expression in pulmonary artery smooth muscle cells: implications for familial pulmonary arterial hypertension.
    Yang J; Davies RJ; Southwood M; Long L; Yang X; Sobolewski A; Upton PD; Trembath RC; Morrell NW
    Circ Res; 2008 May; 102(10):1212-21. PubMed ID: 18436795
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Transforming growth factor-β stimulates Smad1/5 signaling in pulmonary artery smooth muscle cells and fibroblasts of the newborn mouse through ALK1.
    Zhang H; Du L; Zhong Y; Flanders KC; Roberts JD
    Am J Physiol Lung Cell Mol Physiol; 2017 Sep; 313(3):L615-L627. PubMed ID: 28642261
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Bone morphogenetic protein (BMP) type II receptor deletion reveals BMP ligand-specific gain of signaling in pulmonary artery smooth muscle cells.
    Yu PB; Beppu H; Kawai N; Li E; Bloch KD
    J Biol Chem; 2005 Jul; 280(26):24443-50. PubMed ID: 15883158
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 32.