118 related articles for article (PubMed ID: 23937977)
1. Computational studies of novel carbonyl-containing diazabicyclic ligands interacting with α4β2 nicotinic acetylcholine receptor (nAChR) reveal alternative binding modes.
Kombo DC; Mazurov AA; Strachan JP; Bencherif M
Bioorg Med Chem Lett; 2013 Sep; 23(18):5105-13. PubMed ID: 23937977
[TBL] [Abstract][Full Text] [Related]
2. QM-polarized ligand docking accurately predicts the trend in binding affinity of a series of arylmethylene quinuclidine-like derivatives at the α4β2 and α3β4 nicotinic acetylcholine receptors (nAChRs).
Kombo DC; Grinevich VP; Hauser TA; Sidach S; Bencherif M
Bioorg Med Chem Lett; 2013 Sep; 23(17):4842-7. PubMed ID: 23886687
[TBL] [Abstract][Full Text] [Related]
3. Multiple interaction regions in the orthosteric ligand binding domain of the α7 neuronal nicotinic acetylcholine receptor.
Xiao Y; Hammond PS; Mazurov AA; Yohannes D
J Chem Inf Model; 2012 Nov; 52(11):3064-73. PubMed ID: 23092444
[TBL] [Abstract][Full Text] [Related]
4. Discovery of novel α7 nicotinic acetylcholine receptor ligands via pharmacophoric and docking studies of benzylidene anabaseine analogs.
Kombo DC; Mazurov AA; Chewning J; Hammond PS; Tallapragada K; Hauser TA; Speake J; Yohannes D; Caldwell WS
Bioorg Med Chem Lett; 2012 Jan; 22(2):1179-86. PubMed ID: 22177081
[TBL] [Abstract][Full Text] [Related]
5. Comparative study on the use of docking and Bayesian categorization to predict ligand binding to nicotinic acetylcholine receptors (nAChRs) subtypes.
Kombo DC; Bencherif M
J Chem Inf Model; 2013 Dec; 53(12):3212-22. PubMed ID: 24328365
[TBL] [Abstract][Full Text] [Related]
6. Modeling subtype-selective agonists binding with alpha4beta2 and alpha7 nicotinic acetylcholine receptors: effects of local binding and long-range electrostatic interactions.
Huang X; Zheng F; Chen X; Crooks PA; Dwoskin LP; Zhan CG
J Med Chem; 2006 Dec; 49(26):7661-74. PubMed ID: 17181149
[TBL] [Abstract][Full Text] [Related]
7. Computational evidence for the ligand selectivity to the alpha4beta2 and alpha3beta4 nicotinic acetylcholine receptors.
Yuan H; Petukhov PA
Bioorg Med Chem; 2006 Dec; 14(23):7936-42. PubMed ID: 16919961
[TBL] [Abstract][Full Text] [Related]
8. A model for short alpha-neurotoxin bound to nicotinic acetylcholine receptor from Torpedo californica: comparison with long-chain alpha-neurotoxins and alpha-conotoxins.
Mordvintsev DY; Polyak YL; Levtsova OV; Tourleigh YV; Kasheverov IE; Shaitan KV; Utkin YN; Tsetlin VI
Comput Biol Chem; 2005 Dec; 29(6):398-411. PubMed ID: 16290328
[TBL] [Abstract][Full Text] [Related]
9. Identification and pharmacological characterization of 3,6-diazabicyclo[3.1.1]heptane-3-carboxamides as novel ligands for the α4β2 and α6/α3β2β3 nicotinic acetylcholine receptors (nAChRs).
Strachan JP; Kombo DC; Mazurov A; Heemstra R; Bhatti BS; Akireddy R; Murthy S; Miao L; Jett JE; Speake J; Bencherif M
Eur J Med Chem; 2014 Oct; 86():60-74. PubMed ID: 25147147
[TBL] [Abstract][Full Text] [Related]
10. Novel 2-(substituted benzyl)quinuclidines inhibit human α7 and α4β2 nicotinic receptors by different mechanisms.
Arias HR; López JJ; Feuerbach D; Fierro A; Ortells MO; Pérez EG
Int J Biochem Cell Biol; 2013 Nov; 45(11):2420-30. PubMed ID: 23954208
[TBL] [Abstract][Full Text] [Related]
11. Interactions of acetylcholine binding site residues contributing to nicotinic acetylcholine receptor gating: role of residues Y93, Y190, K145 and D200.
Mallipeddi PL; Pedersen SE; Briggs JM
J Mol Graph Model; 2013 Jul; 44():145-54. PubMed ID: 23831994
[TBL] [Abstract][Full Text] [Related]
12. Agonist-induced hump current production in heterologously-expressed human alpha4beta2-nicotinic acetylcholine receptors.
Liu Q; Yu KW; Chang YC; Lukas RJ; Wu J
Acta Pharmacol Sin; 2008 Mar; 29(3):305-19. PubMed ID: 18298895
[TBL] [Abstract][Full Text] [Related]
13. A computational study of the binding of 3-(arylidene) anabaseines to two major brain nicotinic acetylcholine receptors and to the acetylcholine binding protein.
Slavov SH; Radzvilovits M; LeFrancois S; Stoyanova-Slavova IB; Soti F; Kem WR; Katritzky AR
Eur J Med Chem; 2010 Jun; 45(6):2433-46. PubMed ID: 20236734
[TBL] [Abstract][Full Text] [Related]
14. Molecular modeling of human pentameric alpha(7) neuronal nicotinic acetylcholine receptor and its interaction with its agonist and competitive antagonist.
Parthiban M; Rajasekaran MB; Ramakumar S; Shanmughavel P
J Biomol Struct Dyn; 2009 Apr; 26(5):535-47. PubMed ID: 19236104
[TBL] [Abstract][Full Text] [Related]
15. Novel acetylcholine and carbamoylcholine analogues: development of a functionally selective alpha4beta2 nicotinic acetylcholine receptor agonist.
Hansen CP; Jensen AA; Christensen JK; Balle T; Liljefors T; Frølund B
J Med Chem; 2008 Dec; 51(23):7380-95. PubMed ID: 18989912
[TBL] [Abstract][Full Text] [Related]
16. Exploration of the molecular architecture of the orthosteric binding site in the α4β2 nicotinic acetylcholine receptor with analogs of 3-(dimethylamino)butyl dimethylcarbamate (DMABC) and 1-(pyridin-3-yl)-1,4-diazepane.
Bach TB; Jensen AA; Petersen JG; Sørensen TE; Della Volpe S; Liu J; Blaazer AR; van Muijlwijk-Koezen JE; Balle T; Frølund B
Eur J Med Chem; 2015 Sep; 102():425-44. PubMed ID: 26301559
[TBL] [Abstract][Full Text] [Related]
17. Docking studies of benzylidene anabaseine interactions with α7 nicotinic acetylcholine receptor (nAChR) and acetylcholine binding proteins (AChBPs): application to the design of related α7 selective ligands.
Kombo DC; Mazurov A; Tallapragada K; Hammond PS; Chewning J; Hauser TA; Vasquez-Valdivieso M; Yohannes D; Talley TT; Taylor P; Caldwell WS
Eur J Med Chem; 2011 Nov; 46(11):5625-35. PubMed ID: 21986237
[TBL] [Abstract][Full Text] [Related]
18. Imidacloprid and thiacloprid neonicotinoids bind more favourably to cockroach than to honeybee α6 nicotinic acetylcholine receptor: insights from computational studies.
Selvam B; Graton J; Laurent AD; Alamiddine Z; Mathé-Allainmat M; Lebreton J; Coqueret O; Olivier C; Thany SH; Le Questel JY
J Mol Graph Model; 2015 Feb; 55():1-12. PubMed ID: 25424654
[TBL] [Abstract][Full Text] [Related]
19. Ligand selectivity for the acetylcholine binding site of the rat alpha4beta2 and alpha3beta4 nicotinic subtypes investigated by molecular docking.
Bisson WH; Scapozza L; Westera G; Mu L; Schubiger PA
J Med Chem; 2005 Aug; 48(16):5123-30. PubMed ID: 16078832
[TBL] [Abstract][Full Text] [Related]
20. Agonists at the alpha4beta2 nicotinic acetylcholine receptors: structure-activity relationships and molecular modelling.
Tønder JE; Olesen PH
Curr Med Chem; 2001 May; 8(6):651-74. PubMed ID: 11281847
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
