47 related articles for article (PubMed ID: 23938203)
1. Structural basis for the interaction of human β-defensin 6 and its putative chemokine receptor CCR2 and breast cancer microvesicles.
De Paula VS; Gomes NS; Lima LG; Miyamoto CA; Monteiro RQ; Almeida FC; Valente AP
J Mol Biol; 2013 Nov; 425(22):4479-95. PubMed ID: 23938203
[TBL] [Abstract][Full Text] [Related]
2. Human beta-defensin 2 and 3 and their mouse orthologs induce chemotaxis through interaction with CCR2.
Röhrl J; Yang D; Oppenheim JJ; Hehlgans T
J Immunol; 2010 Jun; 184(12):6688-94. PubMed ID: 20483750
[TBL] [Abstract][Full Text] [Related]
3. Integrated solid-state NMR and molecular dynamics modeling determines membrane insertion of human β-defensin analog.
Kang X; Elson C; Penfield J; Kirui A; Chen A; Zhang L; Wang T
Commun Biol; 2019; 2():402. PubMed ID: 31701030
[TBL] [Abstract][Full Text] [Related]
4. Backbone dynamics of the antifungal Psd1 pea defensin and its correlation with membrane interaction by NMR spectroscopy.
de Medeiros LN; Angeli R; Sarzedas CG; Barreto-Bergter E; Valente AP; Kurtenbach E; Almeida FC
Biochim Biophys Acta; 2010 Feb; 1798(2):105-13. PubMed ID: 19632194
[TBL] [Abstract][Full Text] [Related]
5. Probing Oligomerized Conformations of Defensin in the Membrane.
Gan W; Schneidman D; Zhang N; Ma B; Nussinov R
Methods Mol Biol; 2017; 1529():353-362. PubMed ID: 27914061
[TBL] [Abstract][Full Text] [Related]
6. Dynamics-Derived Insights into Complex Formation between the CXCL8 Monomer and CXCR1 N-Terminal Domain: An NMR Study.
Joseph PRB; Spyracopoulos L; Rajarathnam K
Molecules; 2018 Oct; 23(11):. PubMed ID: 30384436
[TBL] [Abstract][Full Text] [Related]
7. A unique ligand-steered strategy for CC chemokine receptor 2 homology modeling to facilitate structure-based virtual screening.
Jin H; Xia J; Liu Z; Wang XS; Zhang L
Chem Biol Drug Des; 2021 Apr; 97(4):944-961. PubMed ID: 33386704
[TBL] [Abstract][Full Text] [Related]
8. Nuclear magnetic resonance solution structure of Pisum sativum defensin 2 provides evidence for the presence of hydrophobic surface-clusters.
Pinheiro-Aguiar R; do Amaral VSG; Pereira IB; Kurtenbach E; Almeida FCL
Proteins; 2020 Jan; 88(1):242-246. PubMed ID: 31294889
[TBL] [Abstract][Full Text] [Related]
9. Insights into the molecular flexibility of θ-defensins by NMR relaxation analysis.
Conibear AC; Wang CK; Bi T; Rosengren KJ; Camarero JA; Craik DJ
J Phys Chem B; 2014 Dec; 118(49):14257-66. PubMed ID: 25375365
[TBL] [Abstract][Full Text] [Related]
10. Discovery and characterization of a functional scFv for CCR2 inhibition via an extracellular loop.
Jasiewicz NE; Brown AD; Deci M; Matysiak S; Earp HS; Nguyen J
Int J Pharm; 2023 Feb; 632():122547. PubMed ID: 36572264
[TBL] [Abstract][Full Text] [Related]
11. PCS-based structure determination of protein-protein complexes.
Saio T; Yokochi M; Kumeta H; Inagaki F
J Biomol NMR; 2010 Apr; 46(4):271-80. PubMed ID: 20300805
[TBL] [Abstract][Full Text] [Related]
12. Discovery of BMS-753426: A Potent Orally Bioavailable Antagonist of CC Chemokine Receptor 2.
Yang MG; Xiao Z; Zhao R; Tebben AJ; Wang B; Cherney RJ; Batt DG; Brown GD; Cvijic ME; Duncia JV; Gallela MA; Gardner DS; Khandelwal P; Malley MF; Pang J; Rose AV; Santella JB; Sarjeant AA; Xu S; Mathur A; Mandlekar S; Vuppugalla R; Zhao Q; Carter PH
ACS Med Chem Lett; 2021 Jun; 12(6):969-975. PubMed ID: 34141082
[TBL] [Abstract][Full Text] [Related]
13. Use of a Conformational-Switching Mechanism to Modulate Exposed Polarity: Discovery of CCR2 Antagonist BMS-741672.
Yang MG; Xiao Z; Cherney RJ; Tebben AJ; Batt DG; Brown GD; Chen J; Cvijic ME; Dabros M; Duncia JV; Galella M; Gardner DS; Khandelwal P; Ko SS; Malley MF; Mo R; Pang J; Rose AV; Santella JB; Shi H; Srivastava A; Traeger SC; Wang B; Xu S; Zhao R; Barrish JC; Mandlekar S; Zhao Q; Carter PH
ACS Med Chem Lett; 2019 Mar; 10(3):300-305. PubMed ID: 30891130
[TBL] [Abstract][Full Text] [Related]
14. Structure of CC chemokine receptor 2 with orthosteric and allosteric antagonists.
Zheng Y; Qin L; Zacarías NV; de Vries H; Han GW; Gustavsson M; Dabros M; Zhao C; Cherney RJ; Carter P; Stamos D; Abagyan R; Cherezov V; Stevens RC; IJzerman AP; Heitman LH; Tebben A; Kufareva I; Handel TM
Nature; 2016 Dec; 540(7633):458-461. PubMed ID: 27926736
[TBL] [Abstract][Full Text] [Related]
15. Discovery of a Potent and Orally Bioavailable Dual Antagonist of CC Chemokine Receptors 2 and 5.
Carter PH; Brown GD; Cherney RJ; Batt DG; Chen J; Clark CM; Cvijic ME; Duncia JV; Ko SS; Mandlekar S; Mo R; Nelson DJ; Pang J; Rose AV; Santella JB; Tebben AJ; Traeger SC; Xu S; Zhao Q; Barrish JC
ACS Med Chem Lett; 2015 Apr; 6(4):439-44. PubMed ID: 25893046
[TBL] [Abstract][Full Text] [Related]
16. Structural basis for the binding of the membrane-proximal C-terminal region of chemokine receptor CCR2 with the cytosolic regulator FROUNT.
Esaki K; Yoshinaga S; Tsuji T; Toda E; Terashima Y; Saitoh T; Kohda D; Kohno T; Osawa M; Ueda T; Shimada I; Matsushima K; Terasawa H
FEBS J; 2014 Dec; 281(24):5552-66. PubMed ID: 25283965
[TBL] [Abstract][Full Text] [Related]
17. Discovery of INCB3284, a Potent, Selective, and Orally Bioavailable hCCR2 Antagonist.
Xue CB; Feng H; Cao G; Huang T; Glenn J; Anand R; Meloni D; Zhang K; Kong L; Wang A; Zhang Y; Zheng C; Xia M; Chen L; Tanaka H; Han Q; Robinson DJ; Modi D; Storace L; Shao L; Sharief V; Li M; Galya LG; Covington M; Scherle P; Diamond S; Emm T; Yeleswaram S; Contel N; Vaddi K; Newton R; Hollis G; Friedman S; Metcalf B
ACS Med Chem Lett; 2011 Jun; 2(6):450-4. PubMed ID: 24900329
[TBL] [Abstract][Full Text] [Related]
18. Genealogy of the CCR5 locus and chemokine system gene variants associated with altered rates of HIV-1 disease progression.
Mummidi S; Ahuja SS; Gonzalez E; Anderson SA; Santiago EN; Stephan KT; Craig FE; O'Connell P; Tryon V; Clark RA; Dolan MJ; Ahuja SK
Nat Med; 1998 Jul; 4(7):786-93. PubMed ID: 9662369
[TBL] [Abstract][Full Text] [Related]
19. Contrasting genetic influence of CCR2 and CCR5 variants on HIV-1 infection and disease progression. Hemophilia Growth and Development Study (HGDS), Multicenter AIDS Cohort Study (MACS), Multicenter Hemophilia Cohort Study (MHCS), San Francisco City Cohort (SFCC), ALIVE Study.
Smith MW; Dean M; Carrington M; Winkler C; Huttley GA; Lomb DA; Goedert JJ; O'Brien TR; Jacobson LP; Kaslow R; Buchbinder S; Vittinghoff E; Vlahov D; Hoots K; Hilgartner MW; O'Brien SJ
Science; 1997 Aug; 277(5328):959-65. PubMed ID: 9252328
[TBL] [Abstract][Full Text] [Related]
20. Molecular cloning and functional expression of two monocyte chemoattractant protein 1 receptors reveals alternative splicing of the carboxyl-terminal tails.
Charo IF; Myers SJ; Herman A; Franci C; Connolly AJ; Coughlin SR
Proc Natl Acad Sci U S A; 1994 Mar; 91(7):2752-6. PubMed ID: 8146186
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
