BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

128 related articles for article (PubMed ID: 23949282)

  • 1. Targeted expression of human folylpolyglutamate synthase for selective enhancement of methotrexate chemotherapy in osteosarcoma cells.
    Bienemann K; Staege MS; Howe SJ; Sena-Esteves M; Hanenberg H; Kramm CM
    Cancer Gene Ther; 2013 Sep; 20(9):514-20. PubMed ID: 23949282
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Effects of folylpolyglutamate synthetase modulation on chemosensitivity of colon cancer cells to 5-fluorouracil and methotrexate.
    Sohn KJ; Smirnakis F; Moskovitz DN; Novakovic P; Yates Z; Lucock M; Croxford R; Kim YI
    Gut; 2004 Dec; 53(12):1825-31. PubMed ID: 15542523
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Chemogene therapy: osteocalcin promoter-based suicide gene therapy in combination with methotrexate in a murine osteosarcoma model.
    Cheon J; Ko SC; Gardner TA; Shirakawa T; Gotoh A; Kao C; Chung LW
    Cancer Gene Ther; 1997; 4(6):359-65. PubMed ID: 9408606
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Folylpolyglutamyl synthetase gene transfer and glioma antifolate sensitivity in culture and in vivo.
    Aghi M; Kramm CM; Breakefield XO
    J Natl Cancer Inst; 1999 Jul; 91(14):1233-41. PubMed ID: 10413425
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Histone deacetylase inhibitors induce FPGS mRNA expression and intracellular accumulation of long-chain methotrexate polyglutamates in childhood acute lymphoblastic leukemia: implications for combination therapy.
    Leclerc GJ; Mou C; Leclerc GM; Mian AM; Barredo JC
    Leukemia; 2010 Mar; 24(3):552-62. PubMed ID: 20072153
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Osteocalcin promoter-based toxic gene therapy for the treatment of osteosarcoma in experimental models.
    Ko SC; Cheon J; Kao C; Gotoh A; Shirakawa T; Sikes RA; Karsenty G; Chung LW
    Cancer Res; 1996 Oct; 56(20):4614-9. PubMed ID: 8840973
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Folylpolyglutamate synthetase expression in antifolate-sensitive and -resistant human cell lines.
    McGuire JJ; Russell CA
    Oncol Res; 1998; 10(4):193-200. PubMed ID: 9778690
    [TBL] [Abstract][Full Text] [Related]  

  • 8. [The mbr-FPGS efficient expression plasmid enhances the sensitivity of Jurkat cells to methotrexate].
    Hu WJ; Sun YJ
    Yi Chuan; 2012 Jun; 34(6):705-10. PubMed ID: 22698741
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Methotrexate selection of long-term culture initiating cells following transduction of CD34(+) cells with a retrovirus containing a mutated human dihydrofolate reductase gene.
    Takebe N; Xu LC; MacKenzie KL; Bertino JR; Moore MA
    Cancer Gene Ther; 2002 Mar; 9(3):308-20. PubMed ID: 11896448
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Anti-tumor efficacy of a transcriptional replication-competent adenovirus, Ad-OC-E1a, for osteosarcoma pulmonary metastasis.
    Li X; Jung C; Liu YH; Bae KH; Zhang YP; Zhang HJ; Vanderputten D; Jeng MH; Gardner TA; Kao C
    J Gene Med; 2006 Jun; 8(6):679-89. PubMed ID: 16570242
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Basal and vitamin D-responsive activity of the rat osteocalcin promoter in stably transfected osteosarcoma cells: requirement of upstream sequences for control by the proximal regulatory domain.
    Frenkel B; Montecino M; Green J; Aslam F; Desai R; Banerjee C; Stein JL; Lian JB; Stein GS
    Endocrinology; 1996 Mar; 137(3):1080-88. PubMed ID: 8603577
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Genomic imbalances associated with methotrexate resistance in human osteosarcoma cell lines detected by comparative genomic hybridization-based techniques.
    Hattinger CM; Reverter-Branchat G; Remondini D; Castellani GC; Benini S; Pasello M; Manara MC; Scotlandi K; Picci P; Serra M
    Eur J Cell Biol; 2003 Sep; 82(9):483-93. PubMed ID: 14582536
    [TBL] [Abstract][Full Text] [Related]  

  • 13. SKA1 induces de novo MTX-resistance in osteosarcoma through inhibiting FPGS transcription.
    Yu W; Min D; Lin F; Zheng S; Tang L; He A; Hu H; Shen Z
    FEBS J; 2019 Jun; 286(12):2399-2414. PubMed ID: 30851225
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Cancer cells as targets for lentivirus-mediated gene transfer and gene therapy.
    Pellinen R; Hakkarainen T; Wahlfors T; Tulimäki K; Ketola A; Tenhunen A; Salonen T; Wahlfors J
    Int J Oncol; 2004 Dec; 25(6):1753-62. PubMed ID: 15547714
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Lentiviral vectors for enhanced gene expression in human hematopoietic cells.
    Ramezani A; Hawley TS; Hawley RG
    Mol Ther; 2000 Nov; 2(5):458-69. PubMed ID: 11082319
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Inherent resistance of human squamous carcinoma cell lines to methotrexate as a result of decreased polyglutamylation of this drug.
    Pizzorno G; Chang YM; McGuire JJ; Bertino JR
    Cancer Res; 1989 Oct; 49(19):5275-80. PubMed ID: 2475246
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Cell-specific and efficient expression in mouse and human B cells by a novel hybrid immunoglobulin promoter in a lentiviral vector.
    Laurie KL; Blundell MP; Baxendale HE; Howe SJ; Sinclair J; Qasim W; Brunsberg U; Thrasher AJ; Holmdahl R; Gustafsson K
    Gene Ther; 2007 Dec; 14(23):1623-31. PubMed ID: 17851547
    [TBL] [Abstract][Full Text] [Related]  

  • 18. [Differential gene expression of folylpolyglutamate synthetase in cytoplasm and mitochondria in acquired methotrexate enantiomers resistant to lung cancer A549 cell lines].
    Zhou HY; He XD; Sun YJ; Fan RZ; Sun L; Shen ZJ
    Zhonghua Yi Xue Za Zhi; 2011 Feb; 91(6):396-400. PubMed ID: 21418912
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Expression and recombination of the EGFP and EYFP genes in lentiviral vectors carrying two heterologous promoters.
    Dijon M; Torne-Celer C; Moreau T; Tonnelle C; Chabannon C
    Cytotherapy; 2005; 7(5):417-26. PubMed ID: 16236631
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Prostate-tumor targeting of gene expression by lentiviral vectors containing elements of the probasin promoter.
    Yu D; Jia WW; Gleave ME; Nelson CC; Rennie PS
    Prostate; 2004 Jun; 59(4):370-82. PubMed ID: 15065085
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.