BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

140 related articles for article (PubMed ID: 23949446)

  • 1. Light-mediated in cell downregulation of G-quadruplex-containing genes using a photo-caged ligand.
    Murat P; Gormally MV; Sanders D; Di Antonio M; Balasubramanian S
    Chem Commun (Camb); 2013 Oct; 49(76):8453-5. PubMed ID: 23949446
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Stabilization of G-quadruplex DNA and inhibition of Bcl-2 expression by a pyridostatin analog.
    Feng Y; Yang D; Chen H; Cheng W; Wang L; Sun H; Tang Y
    Bioorg Med Chem Lett; 2016 Apr; 26(7):1660-3. PubMed ID: 26923693
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Small-molecule-induced DNA damage identifies alternative DNA structures in human genes.
    Rodriguez R; Miller KM; Forment JV; Bradshaw CR; Nikan M; Britton S; Oelschlaegel T; Xhemalce B; Balasubramanian S; Jackson SP
    Nat Chem Biol; 2012 Feb; 8(3):301-10. PubMed ID: 22306580
    [TBL] [Abstract][Full Text] [Related]  

  • 4. G-quadruplex DNA as a molecular target for induced synthetic lethality in cancer cells.
    McLuckie KI; Di Antonio M; Zecchini H; Xian J; Caldas C; Krippendorff BF; Tannahill D; Lowe C; Balasubramanian S
    J Am Chem Soc; 2013 Jul; 135(26):9640-3. PubMed ID: 23782415
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Pyridostatin analogues promote telomere dysfunction and long-term growth inhibition in human cancer cells.
    Müller S; Sanders DA; Di Antonio M; Matsis S; Riou JF; Rodriguez R; Balasubramanian S
    Org Biomol Chem; 2012 Aug; 10(32):6537-46. PubMed ID: 22790277
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Intensive Distribution of G₂-Quaduplexes in the Pseudorabies Virus Genome and Their Sensitivity to Cations and G-Quadruplex Ligands.
    Deng H; Gong B; Yang Z; Li Z; Zhou H; Zhang Y; Niu X; Liu S; Wei D
    Molecules; 2019 Feb; 24(4):. PubMed ID: 30795541
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Discovery of Novel 11-Triazole Substituted Benzofuro[3,2-b]quinolone Derivatives as c-myc G-Quadruplex Specific Stabilizers via Click Chemistry.
    Zeng DY; Kuang GT; Wang SK; Peng W; Lin SL; Zhang Q; Su XX; Hu MH; Wang H; Tan JH; Huang ZS; Gu LQ; Ou TM
    J Med Chem; 2017 Jul; 60(13):5407-5423. PubMed ID: 28514170
    [TBL] [Abstract][Full Text] [Related]  

  • 8. G-quadruplex binders as cytostatic modulators of innate immune genes in cancer cells.
    Miglietta G; Russo M; Duardo RC; Capranico G
    Nucleic Acids Res; 2021 Jul; 49(12):6673-6686. PubMed ID: 34139015
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The G-quadruplex DNA stabilizing drug pyridostatin promotes DNA damage and downregulates transcription of Brca1 in neurons.
    Moruno-Manchon JF; Koellhoffer EC; Gopakumar J; Hambarde S; Kim N; McCullough LD; Tsvetkov AS
    Aging (Albany NY); 2017 Sep; 9(9):1957-1970. PubMed ID: 28904242
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Enantiomers of tetrahedral metal-organic cages: a new class of highly efficient G-quadruplex ligands with potential anticancer activities.
    Xi SF; Bao LY; Lin JG; Liu QZ; Qiu L; Zhang FL; Wang YX; Ding ZD; Li K; Gu ZG
    Chem Commun (Camb); 2016 Aug; 52(67):10261-4. PubMed ID: 27465787
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Downregulation of androgen receptor transcription by promoter g-quadruplex stabilization as a potential alternative treatment for castrate-resistant prostate cancer.
    Mitchell T; Ramos-Montoya A; Di Antonio M; Murat P; Ohnmacht S; Micco M; Jurmeister S; Fryer L; Balasubramanian S; Neidle S; Neal DE
    Biochemistry; 2013 Feb; 52(8):1429-36. PubMed ID: 23363071
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Transcription-associated topoisomerase 2α (TOP2A) activity is a major effector of cytotoxicity induced by G-quadruplex ligands.
    Bossaert M; Pipier A; Riou JF; Noirot C; Nguyên LT; Serre RF; Bouchez O; Defrancq E; Calsou P; Britton S; Gomez D
    Elife; 2021 Jun; 10():. PubMed ID: 34180392
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Molecular recognition of a carboxy pyridostatin toward G-quadruplex structures: Why does it prefer RNA?
    Rocca R; Talarico C; Moraca F; Costa G; Romeo I; Ortuso F; Alcaro S; Artese A
    Chem Biol Drug Des; 2017 Nov; 90(5):919-925. PubMed ID: 28459507
    [TBL] [Abstract][Full Text] [Related]  

  • 14. A novel series of G-quadruplex ligands with selectivity for HIF-expressing osteosarcoma and renal cancer cell lines.
    Lombardo CM; Welsh SJ; Strauss SJ; Dale AG; Todd AK; Nanjunda R; Wilson WD; Neidle S
    Bioorg Med Chem Lett; 2012 Sep; 22(18):5984-8. PubMed ID: 22889802
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Discovery of the first dual G-triplex/G-quadruplex stabilizing compound: a new opportunity in the targeting of G-rich DNA structures?
    Amato J; Pagano A; Cosconati S; Amendola G; Fotticchia I; Iaccarino N; Marinello J; De Magis A; Capranico G; Novellino E; Pagano B; Randazzo A
    Biochim Biophys Acta Gen Subj; 2017 May; 1861(5 Pt B):1271-1280. PubMed ID: 27836755
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Demonstration of ligand decoration, and ligand-induced perturbation, of G-quadruplexes in a plasmid using atomic force microscopy.
    Mela I; Kranaster R; Henderson RM; Balasubramanian S; Edwardson JM
    Biochemistry; 2012 Jan; 51(2):578-85. PubMed ID: 22225525
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Single-Molecule Analysis of Human Telomere Sequence Interactions with G-quadruplex Ligand.
    Zhang L; Zhang K; Rauf S; Dong D; Liu Y; Li J
    Anal Chem; 2016 Apr; 88(8):4533-40. PubMed ID: 27012789
    [TBL] [Abstract][Full Text] [Related]  

  • 18. G-quadruplex binder pyridostatin as an effective multi-target ZIKV inhibitor.
    Zou M; Li JY; Zhang MJ; Li JH; Huang JT; You PD; Liu SW; Zhou CQ
    Int J Biol Macromol; 2021 Nov; 190():178-188. PubMed ID: 34461156
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Ligand-induced conformational changes with cation ejection upon binding to human telomeric DNA G-quadruplexes.
    Marchand A; Granzhan A; Iida K; Tsushima Y; Ma Y; Nagasawa K; Teulade-Fichou MP; Gabelica V
    J Am Chem Soc; 2015 Jan; 137(2):750-6. PubMed ID: 25525863
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Tandem application of ligand-based virtual screening and G4-OAS assay to identify novel G-quadruplex-targeting chemotypes.
    Musumeci D; Amato J; Zizza P; Platella C; Cosconati S; Cingolani C; Biroccio A; Novellino E; Randazzo A; Giancola C; Pagano B; Montesarchio D
    Biochim Biophys Acta Gen Subj; 2017 May; 1861(5 Pt B):1341-1352. PubMed ID: 28130159
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.