BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

232 related articles for article (PubMed ID: 23954429)

  • 1. Chk1 inhibits E2F6 repressor function in response to replication stress to maintain cell-cycle transcription.
    Bertoli C; Klier S; McGowan C; Wittenberg C; de Bruin RA
    Curr Biol; 2013 Sep; 23(17):1629-37. PubMed ID: 23954429
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Phosphorylation of the MBF repressor Yox1p by the DNA replication checkpoint keeps the G1/S cell-cycle transcriptional program active.
    Caetano C; Klier S; de Bruin RA
    PLoS One; 2011 Feb; 6(2):e17211. PubMed ID: 21359180
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Dual regulation of Cdc25A by Chk1 and p53-ATF3 in DNA replication checkpoint control.
    Demidova AR; Aau MY; Zhuang L; Yu Q
    J Biol Chem; 2009 Feb; 284(7):4132-9. PubMed ID: 19060337
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Chk1 is essential for tumor cell viability following activation of the replication checkpoint.
    Cho SH; Toouli CD; Fujii GH; Crain C; Parry D
    Cell Cycle; 2005 Jan; 4(1):131-9. PubMed ID: 15539958
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Activating E2Fs mediate transcriptional regulation of human E2F6 repressor.
    Lyons TE; Salih M; Tuana BS
    Am J Physiol Cell Physiol; 2006 Jan; 290(1):C189-99. PubMed ID: 16107498
    [TBL] [Abstract][Full Text] [Related]  

  • 6. A role for E2F6 in distinguishing G1/S- and G2/M-specific transcription.
    Giangrande PH; Zhu W; Schlisio S; Sun X; Mori S; Gaubatz S; Nevins JR
    Genes Dev; 2004 Dec; 18(23):2941-51. PubMed ID: 15574595
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The MluI cell cycle box (MCB) motifs, but not damage-responsive elements (DREs), are responsible for the transcriptional induction of the rhp51+ gene in response to DNA replication stress.
    Sartagul W; Zhou X; Yamada Y; Ma N; Tanaka K; Furuyashiki T; Ma Y
    PLoS One; 2014; 9(11):e111936. PubMed ID: 25372384
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Chk1- and claspin-dependent but ATR/ATM- and Rad17-independent DNA replication checkpoint response in HeLa cells.
    Rodríguez-Bravo V; Guaita-Esteruelas S; Florensa R; Bachs O; Agell N
    Cancer Res; 2006 Sep; 66(17):8672-9. PubMed ID: 16951182
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Separation of intra-S checkpoint protein contributions to DNA replication fork protection and genomic stability in normal human fibroblasts.
    Smith-Roe SL; Patel SS; Zhou Y; Simpson DA; Rao S; Ibrahim JG; Cordeiro-Stone M; Kaufmann WK
    Cell Cycle; 2013 Jan; 12(2):332-45. PubMed ID: 23255133
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Chk1 instability is coupled to mitotic cell death of p53-deficient cells in response to virus-induced DNA damage signaling.
    Jurvansuu J; Fragkos M; Ingemarsdotter C; Beard P
    J Mol Biol; 2007 Sep; 372(2):397-406. PubMed ID: 17663993
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Chk1 and 14-3-3 proteins inhibit atypical E2Fs to prevent a permanent cell cycle arrest.
    Yuan R; Vos HR; van Es RM; Chen J; Burgering BM; Westendorp B; de Bruin A
    EMBO J; 2018 Mar; 37(5):. PubMed ID: 29363506
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Chk1 dynamics in G2 phase upon replication stress predict daughter cell outcome.
    Lebrec V; Poteau M; Morretton JP; Gavet O
    Dev Cell; 2022 Mar; 57(5):638-653.e5. PubMed ID: 35245445
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Study of the DNA damage checkpoint using Xenopus egg extracts.
    Willis J; DeStephanis D; Patel Y; Gowda V; Yan S
    J Vis Exp; 2012 Nov; (69):e4449. PubMed ID: 23149695
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Analysis of Rad3 and Chk1 protein kinases defines different checkpoint responses.
    Martinho RG; Lindsay HD; Flaggs G; DeMaggio AJ; Hoekstra MF; Carr AM; Bentley NJ
    EMBO J; 1998 Dec; 17(24):7239-49. PubMed ID: 9857181
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The multiple checkpoint functions of CHK1 and CHK2 in maintenance of genome stability.
    Chen Y; Poon RY
    Front Biosci; 2008 May; 13():5016-29. PubMed ID: 18508566
    [TBL] [Abstract][Full Text] [Related]  

  • 16. DNA damage control: regulation and functions of checkpoint kinase 1.
    Smits VA; Gillespie DA
    FEBS J; 2015 Oct; 282(19):3681-92. PubMed ID: 26216057
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Phosphorylation of Minichromosome Maintenance 3 (MCM3) by Checkpoint Kinase 1 (Chk1) Negatively Regulates DNA Replication and Checkpoint Activation.
    Han X; Mayca Pozo F; Wisotsky JN; Wang B; Jacobberger JW; Zhang Y
    J Biol Chem; 2015 May; 290(19):12370-8. PubMed ID: 25809478
    [TBL] [Abstract][Full Text] [Related]  

  • 18. A novel mechanism of checkpoint abrogation conferred by Chk1 downregulation.
    Xiao Z; Xue J; Sowin TJ; Rosenberg SH; Zhang H
    Oncogene; 2005 Feb; 24(8):1403-11. PubMed ID: 15608676
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The F box protein Fbx6 regulates Chk1 stability and cellular sensitivity to replication stress.
    Zhang YW; Brognard J; Coughlin C; You Z; Dolled-Filhart M; Aslanian A; Manning G; Abraham RT; Hunter T
    Mol Cell; 2009 Aug; 35(4):442-53. PubMed ID: 19716789
    [TBL] [Abstract][Full Text] [Related]  

  • 20. ATR and Chk1 suppress a caspase-3-dependent apoptotic response following DNA replication stress.
    Myers K; Gagou ME; Zuazua-Villar P; Rodriguez R; Meuth M
    PLoS Genet; 2009 Jan; 5(1):e1000324. PubMed ID: 19119425
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.