BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

159 related articles for article (PubMed ID: 23962108)

  • 1. The periplasmic cavity of LacY mutant Cys154→Gly: how open is open?
    Jiang X; Driessen AJ; Feringa BL; Kaback HR
    Biochemistry; 2013 Sep; 52(37):6568-74. PubMed ID: 23962108
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Opening the periplasmic cavity in lactose permease is the limiting step for sugar binding.
    Smirnova I; Kasho V; Sugihara J; Kaback HR
    Proc Natl Acad Sci U S A; 2011 Sep; 108(37):15147-51. PubMed ID: 21896727
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Clogging the periplasmic pathway in LacY.
    Nie Y; Zhou Y; Kaback HR
    Biochemistry; 2009 Feb; 48(4):738-43. PubMed ID: 19128028
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The Cys154-->Gly mutation in LacY causes constitutive opening of the hydrophilic periplasmic pathway.
    Nie Y; Sabetfard FE; Kaback HR
    J Mol Biol; 2008 Jun; 379(4):695-703. PubMed ID: 18485365
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Sugar binding induces an outward facing conformation of LacY.
    Smirnova I; Kasho V; Choe JY; Altenbach C; Hubbell WL; Kaback HR
    Proc Natl Acad Sci U S A; 2007 Oct; 104(42):16504-9. PubMed ID: 17925435
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Evidence for an intermediate conformational state of LacY.
    Jiang X; Guan L; Zhou Y; Hong WX; Zhang Q; Kaback HR
    Proc Natl Acad Sci U S A; 2012 Mar; 109(12):E698-704. PubMed ID: 22355148
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Role of the irreplaceable residues in the LacY alternating access mechanism.
    Zhou Y; Jiang X; Kaback HR
    Proc Natl Acad Sci U S A; 2012 Jul; 109(31):12438-42. PubMed ID: 22802658
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Apo-intermediate in the transport cycle of lactose permease (LacY).
    Madej MG; Soro SN; Kaback HR
    Proc Natl Acad Sci U S A; 2012 Oct; 109(44):E2970-8. PubMed ID: 23012238
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Trp replacements for tightly interacting Gly-Gly pairs in LacY stabilize an outward-facing conformation.
    Smirnova I; Kasho V; Sugihara J; Kaback HR
    Proc Natl Acad Sci U S A; 2013 May; 110(22):8876-81. PubMed ID: 23671103
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Engineered occluded apo-intermediate of LacY.
    Smirnova I; Kasho V; Kaback HR
    Proc Natl Acad Sci U S A; 2018 Dec; 115(50):12716-12721. PubMed ID: 30478058
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Residues gating the periplasmic pathway of LacY.
    Zhou Y; Nie Y; Kaback HR
    J Mol Biol; 2009 Nov; 394(2):219-25. PubMed ID: 19781551
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Oversized galactosides as a probe for conformational dynamics in LacY.
    Smirnova I; Kasho V; Jiang X; Chen HM; Withers SG; Kaback HR
    Proc Natl Acad Sci U S A; 2018 Apr; 115(16):4146-4151. PubMed ID: 29602806
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Outward-facing conformers of LacY stabilized by nanobodies.
    Smirnova I; Kasho V; Jiang X; Pardon E; Steyaert J; Kaback HR
    Proc Natl Acad Sci U S A; 2014 Dec; 111(52):18548-53. PubMed ID: 25512549
    [TBL] [Abstract][Full Text] [Related]  

  • 14. An Asymmetric Conformational Change in LacY.
    Smirnova I; Kasho V; Jiang X; Kaback HR
    Biochemistry; 2017 Apr; 56(13):1943-1950. PubMed ID: 28300394
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Lactose permease and the alternating access mechanism.
    Smirnova I; Kasho V; Kaback HR
    Biochemistry; 2011 Nov; 50(45):9684-93. PubMed ID: 21995338
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Real-time conformational changes in LacY.
    Smirnova I; Kasho V; Kaback HR
    Proc Natl Acad Sci U S A; 2014 Jun; 111(23):8440-5. PubMed ID: 24872451
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Role of Conserved Gly-Gly Pairs on the Periplasmic Side of LacY.
    Jiang X; Andersson M; Chau BT; Wong LY; Villafuerte MK; Kaback HR
    Biochemistry; 2016 Aug; 55(31):4326-32. PubMed ID: 27438891
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Crystal structure of a LacY-nanobody complex in a periplasmic-open conformation.
    Jiang X; Smirnova I; Kasho V; Wu J; Hirata K; Ke M; Pardon E; Steyaert J; Yan N; Kaback HR
    Proc Natl Acad Sci U S A; 2016 Nov; 113(44):12420-12425. PubMed ID: 27791182
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Probing of the rates of alternating access in LacY with Trp fluorescence.
    Smirnova I; Kasho V; Sugihara J; Kaback HR
    Proc Natl Acad Sci U S A; 2009 Dec; 106(51):21561-6. PubMed ID: 19959662
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Single-molecule FRET reveals sugar-induced conformational dynamics in LacY.
    Majumdar DS; Smirnova I; Kasho V; Nir E; Kong X; Weiss S; Kaback HR
    Proc Natl Acad Sci U S A; 2007 Jul; 104(31):12640-5. PubMed ID: 17502603
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.