BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

688 related articles for article (PubMed ID: 23962664)

  • 1. Comparison of EJC-enhanced and EJC-independent NMD in human cells reveals two partially redundant degradation pathways.
    Metze S; Herzog VA; Ruepp MD; Mühlemann O
    RNA; 2013 Oct; 19(10):1432-48. PubMed ID: 23962664
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Dissecting the functions of SMG5, SMG7, and PNRC2 in nonsense-mediated mRNA decay of human cells.
    Nicholson P; Gkratsou A; Josi C; Colombo M; Mühlemann O
    RNA; 2018 Apr; 24(4):557-573. PubMed ID: 29348139
    [TBL] [Abstract][Full Text] [Related]  

  • 3. CK2-mediated TEL2 phosphorylation augments nonsense-mediated mRNA decay (NMD) by increase of SMG1 stability.
    Ahn S; Kim J; Hwang J
    Biochim Biophys Acta; 2013 Oct; 1829(10):1047-55. PubMed ID: 23831331
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Processing bodies are not required for mammalian nonsense-mediated mRNA decay.
    Stalder L; Mühlemann O
    RNA; 2009 Jul; 15(7):1265-73. PubMed ID: 19474145
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Transcript-specific characteristics determine the contribution of endo- and exonucleolytic decay pathways during the degradation of nonsense-mediated decay substrates.
    Ottens F; Boehm V; Sibley CR; Ule J; Gehring NH
    RNA; 2017 Aug; 23(8):1224-1236. PubMed ID: 28461625
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Binding of a novel SMG-1-Upf1-eRF1-eRF3 complex (SURF) to the exon junction complex triggers Upf1 phosphorylation and nonsense-mediated mRNA decay.
    Kashima I; Yamashita A; Izumi N; Kataoka N; Morishita R; Hoshino S; Ohno M; Dreyfuss G; Ohno S
    Genes Dev; 2006 Feb; 20(3):355-67. PubMed ID: 16452507
    [TBL] [Abstract][Full Text] [Related]  

  • 7. SMG6 interacts with the exon junction complex via two conserved EJC-binding motifs (EBMs) required for nonsense-mediated mRNA decay.
    Kashima I; Jonas S; Jayachandran U; Buchwald G; Conti E; Lupas AN; Izaurralde E
    Genes Dev; 2010 Nov; 24(21):2440-50. PubMed ID: 20930030
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Mechanism of Nonsense-Mediated mRNA Decay Stimulation by Splicing Factor SRSF1.
    Aznarez I; Nomakuchi TT; Tetenbaum-Novatt J; Rahman MA; Fregoso O; Rees H; Krainer AR
    Cell Rep; 2018 May; 23(7):2186-2198. PubMed ID: 29768215
    [TBL] [Abstract][Full Text] [Related]  

  • 9. NMD factors UPF2 and UPF3 bridge UPF1 to the exon junction complex and stimulate its RNA helicase activity.
    Chamieh H; Ballut L; Bonneau F; Le Hir H
    Nat Struct Mol Biol; 2008 Jan; 15(1):85-93. PubMed ID: 18066079
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Mammalian UPF3A and UPF3B can activate nonsense-mediated mRNA decay independently of their exon junction complex binding.
    Yi Z; Arvola RM; Myers S; Dilsavor CN; Abu Alhasan R; Carter BN; Patton RD; Bundschuh R; Singh G
    EMBO J; 2022 May; 41(10):e109202. PubMed ID: 35451102
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Transcriptome-wide identification of NMD-targeted human mRNAs reveals extensive redundancy between SMG6- and SMG7-mediated degradation pathways.
    Colombo M; Karousis ED; Bourquin J; Bruggmann R; Mühlemann O
    RNA; 2017 Feb; 23(2):189-201. PubMed ID: 27864472
    [TBL] [Abstract][Full Text] [Related]  

  • 12. SMG1 regulates adipogenesis via targeting of staufen1-mediated mRNA decay.
    Cho H; Han S; Park OH; Kim YK
    Biochim Biophys Acta; 2013 Dec; 1829(12):1276-87. PubMed ID: 24185201
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Exon-junction complex components specify distinct routes of nonsense-mediated mRNA decay with differential cofactor requirements.
    Gehring NH; Kunz JB; Neu-Yilik G; Breit S; Viegas MH; Hentze MW; Kulozik AE
    Mol Cell; 2005 Oct; 20(1):65-75. PubMed ID: 16209946
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Interactions between UPF1, eRFs, PABP and the exon junction complex suggest an integrated model for mammalian NMD pathways.
    Ivanov PV; Gehring NH; Kunz JB; Hentze MW; Kulozik AE
    EMBO J; 2008 Mar; 27(5):736-47. PubMed ID: 18256688
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Human nonsense-mediated mRNA decay factor UPF2 interacts directly with eRF3 and the SURF complex.
    López-Perrote A; Castaño R; Melero R; Zamarro T; Kurosawa H; Ohnishi T; Uchiyama A; Aoyagi K; Buchwald G; Kataoka N; Yamashita A; Llorca O
    Nucleic Acids Res; 2016 Feb; 44(4):1909-23. PubMed ID: 26740584
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A novel phosphorylation-independent interaction between SMG6 and UPF1 is essential for human NMD.
    Nicholson P; Josi C; Kurosawa H; Yamashita A; Mühlemann O
    Nucleic Acids Res; 2014 Aug; 42(14):9217-35. PubMed ID: 25053839
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Multiple Nonsense-Mediated mRNA Processes Require
    Nelson JO; Förster D; Frizzell KA; Luschnig S; Metzstein MM
    Genetics; 2018 Aug; 209(4):1073-1084. PubMed ID: 29903866
    [TBL] [Abstract][Full Text] [Related]  

  • 18. CBP80 promotes interaction of Upf1 with Upf2 during nonsense-mediated mRNA decay in mammalian cells.
    Hosoda N; Kim YK; Lejeune F; Maquat LE
    Nat Struct Mol Biol; 2005 Oct; 12(10):893-901. PubMed ID: 16186820
    [TBL] [Abstract][Full Text] [Related]  

  • 19. mRNAs containing NMD-competent premature termination codons are stabilized and translated under UPF1 depletion.
    Kim WK; Yun S; Kwon Y; You KT; Shin N; Kim J; Kim H
    Sci Rep; 2017 Nov; 7(1):15833. PubMed ID: 29158530
    [TBL] [Abstract][Full Text] [Related]  

  • 20. A post-translational regulatory switch on UPF1 controls targeted mRNA degradation.
    Kurosaki T; Li W; Hoque M; Popp MW; Ermolenko DN; Tian B; Maquat LE
    Genes Dev; 2014 Sep; 28(17):1900-16. PubMed ID: 25184677
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 35.