These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

158 related articles for article (PubMed ID: 23964020)

  • 1. Kinesin spindle protein (KSP) inhibitors in combination with chemotherapeutic agents for cancer therapy.
    Song H; Zhou S; Wang R; Li S
    ChemMedChem; 2013 Nov; 8(11):1736-49. PubMed ID: 23964020
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Progress on kinesin spindle protein inhibitors as anti-cancer agents.
    Zhang Y; Xu W
    Anticancer Agents Med Chem; 2008 Aug; 8(6):698-704. PubMed ID: 18690830
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Novel ATP-competitive kinesin spindle protein inhibitors.
    Parrish CA; Adams ND; Auger KR; Burgess JL; Carson JD; Chaudhari AM; Copeland RA; Diamond MA; Donatelli CA; Duffy KJ; Faucette LF; Finer JT; Huffman WF; Hugger ED; Jackson JR; Knight SD; Luo L; Moore ML; Newlander KA; Ridgers LH; Sakowicz R; Shaw AN; Sung CM; Sutton D; Wood KW; Zhang SY; Zimmerman MN; Dhanak D
    J Med Chem; 2007 Oct; 50(20):4939-52. PubMed ID: 17725339
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Tubulin-associated drug targets: Aurora kinases, Polo-like kinases, and others.
    Warner SL; Gray PJ; Von Hoff DD
    Semin Oncol; 2006 Aug; 33(4):436-48. PubMed ID: 16890798
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Discovery of allosteric inhibitors of kinesin spindle protein (KSP) for the treatment of taxane-refractory cancer: MK-0731 and analogs.
    Cox CD; Garbaccio RM
    Anticancer Agents Med Chem; 2010 Nov; 10(9):697-712. PubMed ID: 21235439
    [TBL] [Abstract][Full Text] [Related]  

  • 6. SCH 1473759, a novel Aurora inhibitor, demonstrates enhanced anti-tumor activity in combination with taxanes and KSP inhibitors.
    Basso AD; Liu M; Gray K; Tevar S; Lee S; Liang L; Ponery A; Smith EB; Monsma FJ; Yu T; Zhang Y; Kerekes AD; Esposite S; Xiao Y; Tagat JR; Hicklin DJ; Kirschmeier P
    Cancer Chemother Pharmacol; 2011 Oct; 68(4):923-33. PubMed ID: 21298383
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Recent progress in the identification and clinical evaluation of inhibitors of the mitotic kinesin KSP.
    Knight SD; Parrish CA
    Curr Top Med Chem; 2008; 8(10):888-904. PubMed ID: 18673173
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Ligand- and structure-based in silico studies to identify kinesin spindle protein (KSP) inhibitors as potential anticancer agents.
    Balakumar C; Ramesh M; Tham CL; Khathi SP; Kozielski F; Srinivasulu C; Hampannavar GA; Sayyad N; Soliman ME; Karpoormath R
    J Biomol Struct Dyn; 2018 Nov; 36(14):3687-3704. PubMed ID: 29064326
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Kinesin spindle protein inhibitors in cancer: a patent review (2008 - present).
    Jiang C; You Q
    Expert Opin Ther Pat; 2013 Dec; 23(12):1547-60. PubMed ID: 23978071
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Targeting the kinesin spindle protein: basic principles and clinical implications.
    Sarli V; Giannis A
    Clin Cancer Res; 2008 Dec; 14(23):7583-7. PubMed ID: 19047082
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Discovery of novel spiro 1,3,4-thiadiazolines as potent, orally bioavailable and brain penetrant KSP inhibitors.
    Mansoor UF; Angeles AR; Dai C; Yang L; Vitharana D; Basso AD; Gray K; Tang H; Liu M; Liang L; Allbritton O; Siddiqui MA
    Bioorg Med Chem; 2015 May; 23(10):2424-34. PubMed ID: 25868746
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Discovery and biochemical characterization of selective ATP competitive inhibitors of the human mitotic kinesin KSP.
    Rickert KW; Schaber M; Torrent M; Neilson LA; Tasber ES; Garbaccio R; Coleman PJ; Harvey D; Zhang Y; Yang Y; Marshall G; Lee L; Walsh ES; Hamilton K; Buser CA
    Arch Biochem Biophys; 2008 Jan; 469(2):220-31. PubMed ID: 17999913
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Developments of kinesin spindle protein inhibitors as antitumor agents based on the five-membered heterocycle scaffolds.
    Zhao GD; Wan RZ; Liu ZP
    Curr Med Chem; 2014; 21(23):2691-701. PubMed ID: 24606497
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Synthesis, biological evaluation and molecular docking studies of flavone and isoflavone derivatives as a novel class of KSP (kinesin spindle protein) inhibitors.
    Dong JJ; Li QS; Liu ZP; Wang SF; Zhao MY; Yang YH; Wang XM; Zhu HL
    Eur J Med Chem; 2013; 70():427-33. PubMed ID: 24184776
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Role of KSP Inhibitors as Anti-cancer Therapeutics: An Update.
    Chamariya R; Suvarna V
    Anticancer Agents Med Chem; 2022; 22(14):2517-2538. PubMed ID: 35043768
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Coupling Kinesin Spindle Protein and Aurora B Inhibition with Apoptosis Induction Enhances Oral Cancer Cell Killing.
    Silva JPN; Pinto B; Monteiro L; Silva PMA; Bousbaa H
    Cancers (Basel); 2024 May; 16(11):. PubMed ID: 38893134
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Discovery of tetrahydro-beta-carbolines as inhibitors of the mitotic kinesin KSP.
    Liu F; Yu LQ; Jiang C; Yang L; Wu WT; You QD
    Bioorg Med Chem; 2010 Jun; 18(12):4167-77. PubMed ID: 20537544
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Potentiation of kinesin spindle protein inhibitor-induced cell death by modulation of mitochondrial and death receptor apoptotic pathways.
    Vijapurkar U; Wang W; Herbst R
    Cancer Res; 2007 Jan; 67(1):237-45. PubMed ID: 17210704
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Kinesin spindle protein (KSP) inhibitors. Part 1: The discovery of 3,5-diaryl-4,5-dihydropyrazoles as potent and selective inhibitors of the mitotic kinesin KSP.
    Cox CD; Breslin MJ; Mariano BJ; Coleman PJ; Buser CA; Walsh ES; Hamilton K; Huber HE; Kohl NE; Torrent M; Yan Y; Kuo LC; Hartman GD
    Bioorg Med Chem Lett; 2005 Apr; 15(8):2041-5. PubMed ID: 15808464
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Kinesin spindle protein (KSP) inhibitors. Part 8: Design and synthesis of 1,4-diaryl-4,5-dihydropyrazoles as potent inhibitors of the mitotic kinesin KSP.
    Roecker AJ; Coleman PJ; Mercer SP; Schreier JD; Buser CA; Walsh ES; Hamilton K; Lobell RB; Tao W; Diehl RE; South VJ; Davide JP; Kohl NE; Yan Y; Kuo LC; Li C; Fernandez-Metzler C; Mahan EA; Prueksaritanont T; Hartman GD
    Bioorg Med Chem Lett; 2007 Oct; 17(20):5677-82. PubMed ID: 17766111
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.