BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

186 related articles for article (PubMed ID: 23968501)

  • 1. Inhibiting aberrant signal transducer and activator of transcription protein activation with tetrapodal, small molecule Src homology 2 domain binders: promising agents against multiple myeloma.
    Page BD; Croucher DC; Li ZH; Haftchenary S; Jimenez-Zepeda VH; Atkinson J; Spagnuolo PA; Wong YL; Colaguori R; Lewis AM; Schimmer AD; Trudel S; Gunning PT
    J Med Chem; 2013 Sep; 56(18):7190-200. PubMed ID: 23968501
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A novel non-phosphorylated potential antitumoral peptide inhibits STAT3 biological activity.
    Dourlat J; Liu WQ; Sancier F; Edmonds T; Pamonsinlapatham P; Cruzalegui F; Garbay C
    Biochimie; 2009 Aug; 91(8):996-1002. PubMed ID: 19470402
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Discovery of novel STAT3 small molecule inhibitors via in silico site-directed fragment-based drug design.
    Yu W; Xiao H; Lin J; Li C
    J Med Chem; 2013 Jun; 56(11):4402-12. PubMed ID: 23651330
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Characterization of molecular recognition of STAT3 SH2 domain inhibitors through molecular simulation.
    Park IH; Li C
    J Mol Recognit; 2011; 24(2):254-65. PubMed ID: 21360612
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Strategies and Approaches of Targeting STAT3 for Cancer Treatment.
    Furtek SL; Backos DS; Matheson CJ; Reigan P
    ACS Chem Biol; 2016 Feb; 11(2):308-18. PubMed ID: 26730496
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Signal transducer and activator of transcription 3 (STAT3): a promising target for anticancer therapy.
    Masciocchi D; Gelain A; Villa S; Meneghetti F; Barlocco D
    Future Med Chem; 2011 Apr; 3(5):567-97. PubMed ID: 21526897
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Janus activated kinase 2/signal transducer and activator of transcription 3 pathway mediates icariside II-induced apoptosis in U266 multiple myeloma cells.
    Kim SH; Ahn KS; Jeong SJ; Kwon TR; Jung JH; Yun SM; Han I; Lee SG; Kim DK; Kang M; Chen CY; Lee JW; Kim SH
    Eur J Pharmacol; 2011 Mar; 654(1):10-6. PubMed ID: 21172343
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Structural basis for the binding of high affinity phosphopeptides to Stat3.
    McMurray JS
    Biopolymers; 2008; 90(1):69-79. PubMed ID: 18058821
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Identification of New Shikonin Derivatives as Antitumor Agents Targeting STAT3 SH2 Domain.
    Qiu HY; Zhu X; Luo YL; Lin HY; Tang CY; Qi JL; Pang YJ; Yang RW; Lu GH; Wang XM; Yang YH
    Sci Rep; 2017 Jun; 7(1):2863. PubMed ID: 28588262
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Design, synthesis, and studies of small molecule STAT3 inhibitors.
    Bhasin D; Cisek K; Pandharkar T; Regan N; Li C; Pandit B; Lin J; Li PK
    Bioorg Med Chem Lett; 2008 Jan; 18(1):391-5. PubMed ID: 18006313
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Inhibiting aberrant Stat3 function with molecular therapeutics: a progress report.
    Haftchenary S; Avadisian M; Gunning PT
    Anticancer Drugs; 2011 Feb; 22(2):115-27. PubMed ID: 21063201
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Antitumor activity of a novel oral signal transducer and activator of transcription 3 inhibitor YHO-1701.
    Nishisaka F; Taniguchi K; Tsugane M; Hirata G; Takagi A; Asakawa N; Kurita A; Takahashi H; Ogo N; Shishido Y; Asai A
    Cancer Sci; 2020 May; 111(5):1774-1784. PubMed ID: 32112605
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Identification of a non-phosphorylated, cell permeable, small molecule ligand for the Stat3 SH2 domain.
    Page BD; Fletcher S; Yue P; Li Z; Zhang X; Sharmeen S; Datti A; Wrana JL; Trudel S; Schimmer AD; Turkson J; Gunning PT
    Bioorg Med Chem Lett; 2011 Sep; 21(18):5605-9. PubMed ID: 21788134
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Embelin suppresses STAT3 signaling, proliferation, and survival of multiple myeloma via the protein tyrosine phosphatase PTEN.
    Heo JY; Kim HJ; Kim SM; Park KR; Park SY; Kim SW; Nam D; Jang HJ; Lee SG; Ahn KS; Kim SH; Shim BS; Choi SH; Ahn KS
    Cancer Lett; 2011 Sep; 308(1):71-80. PubMed ID: 21565443
    [TBL] [Abstract][Full Text] [Related]  

  • 15. SD-1029 inhibits signal transducer and activator of transcription 3 nuclear translocation.
    Duan Z; Bradner JE; Greenberg E; Levine R; Foster R; Mahoney J; Seiden MV
    Clin Cancer Res; 2006 Nov; 12(22):6844-52. PubMed ID: 17121906
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A cell-permeable Stat3 SH2 domain mimetic inhibits Stat3 activation and induces antitumor cell effects in vitro.
    Zhao W; Jaganathan S; Turkson J
    J Biol Chem; 2010 Nov; 285(46):35855-65. PubMed ID: 20807764
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Investigation of the binding determinants of phosphopeptides targeted to the SRC homology 2 domain of the signal transducer and activator of transcription 3. Development of a high-affinity peptide inhibitor.
    Coleman DR; Ren Z; Mandal PK; Cameron AG; Dyer GA; Muranjan S; Campbell M; Chen X; McMurray JS
    J Med Chem; 2005 Oct; 48(21):6661-70. PubMed ID: 16220982
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Rational drug design of benzothiazole-based derivatives as potent signal transducer and activator of transcription 3 (STAT3) signaling pathway inhibitors.
    Gao D; Jin N; Fu Y; Zhu Y; Wang Y; Wang T; Chen Y; Zhang M; Xiao Q; Huang M; Li Y
    Eur J Med Chem; 2021 Apr; 216():113333. PubMed ID: 33689932
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Abrogation of signal transducer and activator of transcription 3 reactivation after Src kinase inhibition results in synergistic antitumor effects.
    Johnson FM; Saigal B; Tran H; Donato NJ
    Clin Cancer Res; 2007 Jul; 13(14):4233-44. PubMed ID: 17634553
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Morin inhibits STAT3 tyrosine 705 phosphorylation in tumor cells through activation of protein tyrosine phosphatase SHP1.
    Gupta SC; Phromnoi K; Aggarwal BB
    Biochem Pharmacol; 2013 Apr; 85(7):898-912. PubMed ID: 23279849
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.