These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

296 related articles for article (PubMed ID: 23969025)

  • 1. ITPA (inosine triphosphate pyrophosphatase): from surveillance of nucleotide pools to human disease and pharmacogenetics.
    Simone PD; Pavlov YI; Borgstahl GEO
    Mutat Res; 2013; 753(2):131-146. PubMed ID: 23969025
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The human ITPA polymorphic variant P32T is destabilized by the unpacking of the hydrophobic core.
    Simone PD; Struble LR; Kellezi A; Brown CA; Grabow CE; Khutsishvili I; Marky LA; Pavlov YI; Borgstahl GE
    J Struct Biol; 2013 Jun; 182(3):197-208. PubMed ID: 23528839
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Functional study of the P32T ITPA variant associated with drug sensitivity in humans.
    Stepchenkova EI; Tarakhovskaya ER; Spitler K; Frahm C; Menezes MR; Simone PD; Kolar C; Marky LA; Borgstahl GE; Pavlov YI
    J Mol Biol; 2009 Sep; 392(3):602-13. PubMed ID: 19631656
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Inosine Triphosphate Pyrophosphatase (ITPase): Functions, Mutations, Polymorphisms and Its Impact on Cancer Therapies.
    Zamzami MA
    Cells; 2022 Jan; 11(3):. PubMed ID: 35159194
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Pivotal role of inosine triphosphate pyrophosphatase in maintaining genome stability and the prevention of apoptosis in human cells.
    Menezes MR; Waisertreiger IS; Lopez-Bertoni H; Luo X; Pavlov YI
    PLoS One; 2012; 7(2):e32313. PubMed ID: 22384212
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Quantitative in vitro and in vivo characterization of the human P32T mutant ITPase.
    Herting G; Barber K; Zappala MR; Cunningham RP; Burgis NE
    Biochim Biophys Acta; 2010 Feb; 1802(2):269-74. PubMed ID: 19914375
    [TBL] [Abstract][Full Text] [Related]  

  • 7. NUDT16 and ITPA play a dual protective role in maintaining chromosome stability and cell growth by eliminating dIDP/IDP and dITP/ITP from nucleotide pools in mammals.
    Abolhassani N; Iyama T; Tsuchimoto D; Sakumi K; Ohno M; Behmanesh M; Nakabeppu Y
    Nucleic Acids Res; 2010 May; 38(9):2891-903. PubMed ID: 20081199
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Structural dynamics of inosine triphosphate pyrophosphatase (ITPA) protein and two clinically relevant mutants: molecular dynamics simulations.
    Houndonougbo Y; Pugh B; VanWormer K; April C; Burgis N
    J Biomol Struct Dyn; 2021 Mar; 39(4):1236-1247. PubMed ID: 32129147
    [TBL] [Abstract][Full Text] [Related]  

  • 9. NUDT16 is a (deoxy)inosine diphosphatase, and its deficiency induces accumulation of single-strand breaks in nuclear DNA and growth arrest.
    Iyama T; Abolhassani N; Tsuchimoto D; Nonaka M; Nakabeppu Y
    Nucleic Acids Res; 2010 Aug; 38(14):4834-43. PubMed ID: 20385596
    [TBL] [Abstract][Full Text] [Related]  

  • 10. ITPA protein, an enzyme that eliminates deaminated purine nucleoside triphosphates in cells.
    Sakumi K; Abolhassani N; Behmanesh M; Iyama T; Tsuchimoto D; Nakabeppu Y
    Mutat Res; 2010 Nov; 703(1):43-50. PubMed ID: 20601097
    [TBL] [Abstract][Full Text] [Related]  

  • 11. RNAi mediated gene silencing of ITPA using a targeted nanocarrier: Apoptosis induction in SKBR3 cancer cells.
    Charbgoo F; Behmanesh M; Nikkhah M; Kane EG
    Clin Exp Pharmacol Physiol; 2017 Aug; 44(8):888-894. PubMed ID: 28464292
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Elevated Levels of DNA Strand Breaks Induced by a Base Analog in the Human Cell Line with the P32T ITPA Variant.
    Waisertreiger IS; Menezes MR; Randazzo J; Pavlov YI
    J Nucleic Acids; 2010 Sep; 2010():. PubMed ID: 20936128
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Molecular basis of the antimutagenic activity of the house-cleaning inosine triphosphate pyrophosphatase RdgB from Escherichia coli.
    Savchenko A; Proudfoot M; Skarina T; Singer A; Litvinova O; Sanishvili R; Brown G; Chirgadze N; Yakunin AF
    J Mol Biol; 2007 Dec; 374(4):1091-103. PubMed ID: 17976651
    [TBL] [Abstract][Full Text] [Related]  

  • 14. An inosine triphosphate pyrophosphatase safeguards plant nucleic acids from aberrant purine nucleotides.
    Straube H; Straube J; Rinne J; Fischer L; Niehaus M; Witte CP; Herde M
    New Phytol; 2023 Mar; 237(5):1759-1775. PubMed ID: 36464781
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Cloning, expression, and characterization of a human inosine triphosphate pyrophosphatase encoded by the itpa gene.
    Lin S; McLennan AG; Ying K; Wang Z; Gu S; Jin H; Wu C; Liu W; Yuan Y; Tang R; Xie Y; Mao Y
    J Biol Chem; 2001 Jun; 276(22):18695-701. PubMed ID: 11278832
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Inosine triphosphate pyrophosphatase and thiopurine s-methyltransferase genotypes relationship to azathioprine-induced myelosuppression.
    Zelinkova Z; Derijks LJ; Stokkers PC; Vogels EW; van Kampen AH; Curvers WL; Cohn D; van Deventer SJ; Hommes DW
    Clin Gastroenterol Hepatol; 2006 Jan; 4(1):44-9. PubMed ID: 16431304
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Adverse drug reactions to azathioprine therapy are associated with polymorphism in the gene encoding inosine triphosphate pyrophosphatase (ITPase).
    Marinaki AM; Ansari A; Duley JA; Arenas M; Sumi S; Lewis CM; Shobowale-Bakre el-M; Escuredo E; Fairbanks LD; Sanderson JD
    Pharmacogenetics; 2004 Mar; 14(3):181-7. PubMed ID: 15167706
    [TBL] [Abstract][Full Text] [Related]  

  • 18. A comprehensive screening system for damaged nucleotide-binding proteins.
    Tsuchimoto D; Iyama T; Nonaka M; Abolhassani N; Ohta E; Sakumi K; Nakabeppu Y
    Mutat Res; 2010 Nov; 703(1):37-42. PubMed ID: 20542141
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Meta-analysis: Inosine triphosphate pyrophosphatase polymorphisms and thiopurine toxicity in the treatment of inflammatory bowel disease.
    Van Dieren JM; Hansen BE; Kuipers EJ; Nieuwenhuis EE; Van der Woude CJ
    Aliment Pharmacol Ther; 2007 Sep; 26(5):643-52. PubMed ID: 17697198
    [TBL] [Abstract][Full Text] [Related]  

  • 20. A disease spectrum for ITPA variation: advances in biochemical and clinical research.
    Burgis NE
    J Biomed Sci; 2016 Oct; 23(1):73. PubMed ID: 27770805
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.