These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

114 related articles for article (PubMed ID: 23973080)

  • 1. Methods for studying microtubule binding site interactions: zampanolide as a covalent binding agent.
    Field JJ; Calvo E; Northcote PT; Miller JH; Altmann KH; Díaz JF
    Methods Cell Biol; 2013; 115():303-25. PubMed ID: 23973080
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Zampanolide, a Microtubule-Stabilizing Agent, Is Active in Resistant Cancer Cells and Inhibits Cell Migration.
    Field JJ; Northcote PT; Paterson I; Altmann KH; Díaz JF; Miller JH
    Int J Mol Sci; 2017 May; 18(5):. PubMed ID: 28467385
    [TBL] [Abstract][Full Text] [Related]  

  • 3. βI-tubulin mutations in the laulimalide/peloruside binding site mediate drug sensitivity by altering drug-tubulin interactions and microtubule stability.
    Kanakkanthara A; Rowe MR; Field JJ; Northcote PT; Teesdale-Spittle PH; Miller JH
    Cancer Lett; 2015 Sep; 365(2):251-60. PubMed ID: 26052091
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Cyclostreptin binds covalently to microtubule pores and lumenal taxoid binding sites.
    Buey RM; Calvo E; Barasoain I; Pineda O; Edler MC; Matesanz R; Cerezo G; Vanderwal CD; Day BW; Sorensen EJ; López JA; Andreu JM; Hamel E; Díaz JF
    Nat Chem Biol; 2007 Feb; 3(2):117-25. PubMed ID: 17206139
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Zampanolide Binding to Tubulin Indicates Cross-Talk of Taxane Site with Colchicine and Nucleotide Sites.
    Field JJ; Pera B; Gallego JE; Calvo E; Rodríguez-Salarichs J; Sáez-Calvo G; Zuwerra D; Jordi M; Andreu JM; Prota AE; Ménchon G; Miller JH; Altmann KH; Díaz JF
    J Nat Prod; 2018 Mar; 81(3):494-505. PubMed ID: 29023132
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Peloruside A does not bind to the taxoid site on beta-tubulin and retains its activity in multidrug-resistant cell lines.
    Gaitanos TN; Buey RM; Díaz JF; Northcote PT; Teesdale-Spittle P; Andreu JM; Miller JH
    Cancer Res; 2004 Aug; 64(15):5063-7. PubMed ID: 15289305
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Zampanolide, a potent new microtubule-stabilizing agent, covalently reacts with the taxane luminal site in tubulin α,β-heterodimers and microtubules.
    Field JJ; Pera B; Calvo E; Canales A; Zurwerra D; Trigili C; Rodríguez-Salarichs J; Matesanz R; Kanakkanthara A; Wakefield SJ; Singh AJ; Jiménez-Barbero J; Northcote P; Miller JH; López JA; Hamel E; Barasoain I; Altmann KH; Díaz JF
    Chem Biol; 2012 Jun; 19(6):686-98. PubMed ID: 22726683
    [TBL] [Abstract][Full Text] [Related]  

  • 8. A unique mode of microtubule stabilization induced by peloruside A.
    Huzil JT; Chik JK; Slysz GW; Freedman H; Tuszynski J; Taylor RE; Sackett DL; Schriemer DC
    J Mol Biol; 2008 May; 378(5):1016-30. PubMed ID: 18405918
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Distinct pose of discodermolide in taxol binding pocket drives a complementary mode of microtubule stabilization.
    Khrapunovich-Baine M; Menon V; Verdier-Pinard P; Smith AB; Angeletti RH; Fiser A; Horwitz SB; Xiao H
    Biochemistry; 2009 Dec; 48(49):11664-77. PubMed ID: 19863156
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Structural basis of microtubule stabilization by laulimalide and peloruside A.
    Prota AE; Bargsten K; Northcote PT; Marsh M; Altmann KH; Miller JH; Díaz JF; Steinmetz MO
    Angew Chem Int Ed Engl; 2014 Feb; 53(6):1621-5. PubMed ID: 24470331
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Molecular mechanism of action of microtubule-stabilizing anticancer agents.
    Prota AE; Bargsten K; Zurwerra D; Field JJ; Díaz JF; Altmann KH; Steinmetz MO
    Science; 2013 Feb; 339(6119):587-90. PubMed ID: 23287720
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The microtubule-pore gatekeeper.
    Snyder JP
    Nat Chem Biol; 2007 Feb; 3(2):81-2. PubMed ID: 17235340
    [No Abstract]   [Full Text] [Related]  

  • 13. Zampanolide and dactylolide: cytotoxic tubulin-assembly agents and promising anticancer leads.
    Chen QH; Kingston DG
    Nat Prod Rep; 2014 Sep; 31(9):1202-26. PubMed ID: 24945566
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The binding sites of microtubule-stabilizing agents.
    Field JJ; Díaz JF; Miller JH
    Chem Biol; 2013 Mar; 20(3):301-15. PubMed ID: 23521789
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Cyclostreptin and microtubules: is a low-affinity binding site required?
    Prussia AJ; Yang Y; Geballe MT; Snyder JP
    Chembiochem; 2010 Jan; 11(1):101-9. PubMed ID: 19946930
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Peloruside A synergizes with other microtubule stabilizing agents in cultured cancer cell lines.
    Wilmes A; Bargh K; Kelly C; Northcote PT; Miller JH
    Mol Pharm; 2007; 4(2):269-80. PubMed ID: 17397239
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Hallmarks of molecular action of microtubule stabilizing agents: effects of epothilone B, ixabepilone, peloruside A, and laulimalide on microtubule conformation.
    Khrapunovich-Baine M; Menon V; Yang CP; Northcote PT; Miller JH; Angeletti RH; Fiser A; Horwitz SB; Xiao H
    J Biol Chem; 2011 Apr; 286(13):11765-78. PubMed ID: 21245138
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Cell-based and biochemical structure-activity analyses of analogs of the microtubule stabilizer dictyostatin.
    Raccor BS; Vogt A; Sikorski RP; Madiraju C; Balachandran R; Montgomery K; Shin Y; Fukui Y; Jung WH; Curran DP; Day BW
    Mol Pharmacol; 2008 Mar; 73(3):718-26. PubMed ID: 18073274
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Structural insight into the role of Gln293Met mutation on the Peloruside A/Laulimalide association with αβ-tubulin from molecular dynamics simulations, binding free energy calculations and weak interactions analysis.
    Zúñiga MA; Alderete JB; Jaña GA; Jiménez VA
    J Comput Aided Mol Des; 2017 Jul; 31(7):643-652. PubMed ID: 28597356
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Non-taxoid site microtubule-stabilizing drugs work independently of tau overexpression in mouse N2a neuroblastoma cells.
    Das V; Miller JH
    Brain Res; 2012 Dec; 1489():121-32. PubMed ID: 23085090
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.