These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

259 related articles for article (PubMed ID: 23981118)

  • 1. Recent progress in understanding activity cliffs and their utility in medicinal chemistry.
    Stumpfe D; Hu Y; Dimova D; Bajorath J
    J Med Chem; 2014 Jan; 57(1):18-28. PubMed ID: 23981118
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Do medicinal chemists learn from activity cliffs? A systematic evaluation of cliff progression in evolving compound data sets.
    Dimova D; Heikamp K; Stumpfe D; Bajorath J
    J Med Chem; 2013 Apr; 56(8):3339-45. PubMed ID: 23527828
    [TBL] [Abstract][Full Text] [Related]  

  • 3. MMP-Cliffs: systematic identification of activity cliffs on the basis of matched molecular pairs.
    Hu X; Hu Y; Vogt M; Stumpfe D; Bajorath J
    J Chem Inf Model; 2012 May; 52(5):1138-45. PubMed ID: 22489665
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Activity cliff networks for medicinal chemistry.
    Stumpfe D; Bajorath J
    Drug Dev Res; 2014 Aug; 75(5):291-8. PubMed ID: 25160069
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Method for the evaluation of structure-activity relationship information associated with coordinated activity cliffs.
    Dimova D; Stumpfe D; Bajorath J
    J Med Chem; 2014 Aug; 57(15):6553-63. PubMed ID: 25014781
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Prediction of individual compounds forming activity cliffs using emerging chemical patterns.
    Namasivayam V; Iyer P; Bajorath J
    J Chem Inf Model; 2013 Dec; 53(12):3131-9. PubMed ID: 24304008
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Prediction of activity cliffs using support vector machines.
    Heikamp K; Hu X; Yan A; Bajorath J
    J Chem Inf Model; 2012 Sep; 52(9):2354-65. PubMed ID: 22894655
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Exploring Activity Cliffs from a Chemoinformatics Perspective.
    Bajorath J
    Mol Inform; 2014 Jun; 33(6-7):438-42. PubMed ID: 27485979
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Extending the activity cliff concept: structural categorization of activity cliffs and systematic identification of different types of cliffs in the ChEMBL database.
    Hu Y; Bajorath J
    J Chem Inf Model; 2012 Jul; 52(7):1806-11. PubMed ID: 22758389
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Extraction of SAR information from activity cliff clusters via matching molecular series.
    Dimova D; Bajorath J
    Eur J Med Chem; 2014 Nov; 87():454-60. PubMed ID: 25282268
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Frequency of occurrence and potency range distribution of activity cliffs in bioactive compounds.
    Stumpfe D; Bajorath J
    J Chem Inf Model; 2012 Sep; 52(9):2348-53. PubMed ID: 22866827
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Monitoring global growth of activity cliff information over time and assessing activity cliff frequencies and distributions.
    Stumpfe D; Bajorath J
    Future Med Chem; 2015 Aug; 7(12):1565-79. PubMed ID: 26334207
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Activity cliff clusters as a source of structure-activity relationship information.
    Dimova D; Stumpfe D; Hu Y; Bajorath J
    Expert Opin Drug Discov; 2015 May; 10(5):441-7. PubMed ID: 25715967
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Activity cliffs: facts or artifacts?
    Medina-Franco JL
    Chem Biol Drug Des; 2013 May; 81(5):553-6. PubMed ID: 23375049
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Activity cliffs in drug discovery: Dr Jekyll or Mr Hyde?
    Cruz-Monteagudo M; Medina-Franco JL; Pérez-Castillo Y; Nicolotti O; Cordeiro MN; Borges F
    Drug Discov Today; 2014 Aug; 19(8):1069-80. PubMed ID: 24560935
    [TBL] [Abstract][Full Text] [Related]  

  • 16. From activity cliffs to activity ridges: informative data structures for SAR analysis.
    Vogt M; Huang Y; Bajorath J
    J Chem Inf Model; 2011 Aug; 51(8):1848-56. PubMed ID: 21761918
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Identification of Interaction Hot Spots in Structures of Drug Targets on the Basis of Three-Dimensional Activity Cliff Information.
    Furtmann N; Hu Y; Gütschow M; Bajorath J
    Chem Biol Drug Des; 2015 Dec; 86(6):1458-65. PubMed ID: 26094578
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Comprehensive analysis of three-dimensional activity cliffs formed by kinase inhibitors with different binding modes and cliff mapping of structural analogues.
    Furtmann N; Hu Y; Bajorath J
    J Med Chem; 2015 Jan; 58(1):252-64. PubMed ID: 25054653
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Advancing the activity cliff concept.
    Hu Y; Stumpfe D; Bajorath J
    F1000Res; 2013; 2():199. PubMed ID: 24555097
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Activity cliffs and activity cliff generators based on chemotype-related activity landscapes.
    Pérez-Villanueva J; Méndez-Lucio O; Soria-Arteche O; Medina-Franco JL
    Mol Divers; 2015 Nov; 19(4):1021-35. PubMed ID: 26150300
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.