BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

284 related articles for article (PubMed ID: 23985533)

  • 1. The importance of Raf dimerization in cell signaling.
    Freeman AK; Ritt DA; Morrison DK
    Small GTPases; 2013; 4(3):180-5. PubMed ID: 23985533
    [TBL] [Abstract][Full Text] [Related]  

  • 2. RAF inhibitors prime wild-type RAF to activate the MAPK pathway and enhance growth.
    Hatzivassiliou G; Song K; Yen I; Brandhuber BJ; Anderson DJ; Alvarado R; Ludlam MJ; Stokoe D; Gloor SL; Vigers G; Morales T; Aliagas I; Liu B; Sideris S; Hoeflich KP; Jaiswal BS; Seshagiri S; Koeppen H; Belvin M; Friedman LS; Malek S
    Nature; 2010 Mar; 464(7287):431-5. PubMed ID: 20130576
    [TBL] [Abstract][Full Text] [Related]  

  • 3. RAF inhibitors transactivate RAF dimers and ERK signalling in cells with wild-type BRAF.
    Poulikakos PI; Zhang C; Bollag G; Shokat KM; Rosen N
    Nature; 2010 Mar; 464(7287):427-30. PubMed ID: 20179705
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Effects of Raf dimerization and its inhibition on normal and disease-associated Raf signaling.
    Freeman AK; Ritt DA; Morrison DK
    Mol Cell; 2013 Feb; 49(4):751-8. PubMed ID: 23352452
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Targeting Aberrant RAS/RAF/MEK/ERK Signaling for Cancer Therapy.
    Degirmenci U; Wang M; Hu J
    Cells; 2020 Jan; 9(1):. PubMed ID: 31941155
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Mathematical modelling unveils the essential role of cellular phosphatases in the inhibition of RAF-MEK-ERK signalling by sorafenib in hepatocellular carcinoma cells.
    Saidak Z; Giacobbi AS; Louandre C; Sauzay C; Mammeri Y; Galmiche A
    Cancer Lett; 2017 Apr; 392():1-8. PubMed ID: 28161506
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Dissecting RAF Inhibitor Resistance by Structure-based Modeling Reveals Ways to Overcome Oncogenic RAS Signaling.
    Rukhlenko OS; Khorsand F; Krstic A; Rozanc J; Alexopoulos LG; Rauch N; Erickson KE; Hlavacek WS; Posner RG; Gómez-Coca S; Rosta E; Fitzgibbon C; Matallanas D; Rauch J; Kolch W; Kholodenko BN
    Cell Syst; 2018 Aug; 7(2):161-179.e14. PubMed ID: 30007540
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Novel RAF-directed approaches to overcome current clinical limits and block the RAS/RAF node.
    Scardaci R; Berlinska E; Scaparone P; Vietti Michelina S; Garbo E; Novello S; Santamaria D; Ambrogio C
    Mol Oncol; 2024 Jun; 18(6):1355-1377. PubMed ID: 38362705
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Bromodomain containing protein represses the Ras/Raf/MEK/ERK pathway to attenuate human hepatoma cell proliferation during HCV infection.
    Zhang Q; Wei L; Yang H; Yang W; Yang Q; Zhang Z; Wu K; Wu J
    Cancer Lett; 2016 Feb; 371(1):107-16. PubMed ID: 26620707
    [TBL] [Abstract][Full Text] [Related]  

  • 10. RAF kinase dimerization: implications for drug discovery and clinical outcomes.
    Brummer T; McInnes C
    Oncogene; 2020 May; 39(21):4155-4169. PubMed ID: 32269299
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Ras-Mediated Activation of the Raf Family Kinases.
    Terrell EM; Morrison DK
    Cold Spring Harb Perspect Med; 2019 Jan; 9(1):. PubMed ID: 29358316
    [TBL] [Abstract][Full Text] [Related]  

  • 12. RAF inhibitor-induced KSR1/B-RAF binding and its effects on ERK cascade signaling.
    McKay MM; Ritt DA; Morrison DK
    Curr Biol; 2011 Apr; 21(7):563-8. PubMed ID: 21458265
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Drug discovery: inhibitors that activate.
    Cichowski K; Jänne PA
    Nature; 2010 Mar; 464(7287):358-9. PubMed ID: 20237552
    [No Abstract]   [Full Text] [Related]  

  • 14. RAS and downstream RAF-MEK and PI3K-AKT signaling in neuronal development, function and dysfunction.
    Zhong J
    Biol Chem; 2016 Mar; 397(3):215-22. PubMed ID: 26760308
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Asperolide A, a marine-derived tetranorditerpenoid, induces G2/M arrest in human NCI-H460 lung carcinoma cells, is mediated by p53-p21 stabilization and modulated by Ras/Raf/MEK/ERK signaling pathway.
    Lv C; Sun W; Sun H; Wei S; Chen R; Wang B; Huang C
    Mar Drugs; 2013 Jan; 11(2):316-31. PubMed ID: 23434831
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Targeting the Raf-MEK-ERK mitogen-activated protein kinase cascade for the treatment of cancer.
    Roberts PJ; Der CJ
    Oncogene; 2007 May; 26(22):3291-310. PubMed ID: 17496923
    [TBL] [Abstract][Full Text] [Related]  

  • 17. miR-520c and miR-373 upregulate MMP9 expression by targeting mTOR and SIRT1, and activate the Ras/Raf/MEK/Erk signaling pathway and NF-κB factor in human fibrosarcoma cells.
    Liu P; Wilson MJ
    J Cell Physiol; 2012 Feb; 227(2):867-76. PubMed ID: 21898400
    [TBL] [Abstract][Full Text] [Related]  

  • 18. RAF suppression synergizes with MEK inhibition in KRAS mutant cancer cells.
    Lamba S; Russo M; Sun C; Lazzari L; Cancelliere C; Grernrum W; Lieftink C; Bernards R; Di Nicolantonio F; Bardelli A
    Cell Rep; 2014 Sep; 8(5):1475-83. PubMed ID: 25199829
    [TBL] [Abstract][Full Text] [Related]  

  • 19. 1Alpha,25-dihydroxyvitamin D3-mediated stimulation of steroid sulphatase activity in myeloid leukaemic cell lines requires VDRnuc-mediated activation of the RAS/RAF/ERK-MAP kinase signalling pathway.
    Hughes PJ; Brown G
    J Cell Biochem; 2006 Jun; 98(3):590-617. PubMed ID: 16440327
    [TBL] [Abstract][Full Text] [Related]  

  • 20. δ and γ tocotrienols suppress human hepatocellular carcinoma cell proliferation via regulation of Ras-Raf-MEK-ERK pathway-associated upstream signaling.
    Burdeos GC; Ito J; Eitsuka T; Nakagawa K; Kimura F; Miyazawa T
    Food Funct; 2016 Oct; 7(10):4170-4174. PubMed ID: 27713963
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.