47 related articles for article (PubMed ID: 23985689)
1. Discovery of novel inhibitors of LEDGF/p75-IN protein-protein interactions.
Sanchez TW; Debnath B; Christ F; Otake H; Debyser Z; Neamati N
Bioorg Med Chem; 2013 Feb; 21(4):957-63. PubMed ID: 23306052
[TBL] [Abstract][Full Text] [Related]
2. Molecular modeling study on the allosteric inhibition mechanism of HIV-1 integrase by LEDGF/p75 binding site inhibitors.
Xue W; Liu H; Yao X
PLoS One; 2014; 9(3):e90799. PubMed ID: 24599328
[TBL] [Abstract][Full Text] [Related]
3. Dual inhibition of HIV-1 replication by integrase-LEDGF allosteric inhibitors is predominant at the post-integration stage.
Le Rouzic E; Bonnard D; Chasset S; Bruneau JM; Chevreuil F; Le Strat F; Nguyen J; Beauvoir R; Amadori C; Brias J; Vomscheid S; Eiler S; Lévy N; Delelis O; Deprez E; Saïb A; Zamborlini A; Emiliani S; Ruff M; Ledoussal B; Moreau F; Benarous R
Retrovirology; 2013 Nov; 10():144. PubMed ID: 24261564
[TBL] [Abstract][Full Text] [Related]
4. A highly potent and safe pyrrolopyridine-based allosteric HIV-1 integrase inhibitor targeting host LEDGF/p75-integrase interaction site.
Maehigashi T; Ahn S; Kim UI; Lindenberger J; Oo A; Koneru PC; Mahboubi B; Engelman AN; Kvaratskhelia M; Kim K; Kim B
PLoS Pathog; 2021 Jul; 17(7):e1009671. PubMed ID: 34293041
[TBL] [Abstract][Full Text] [Related]
5. Inhibiting HIV-1 integrase by shifting its oligomerization equilibrium.
Hayouka Z; Rosenbluh J; Levin A; Loya S; Lebendiker M; Veprintsev D; Kotler M; Hizi A; Loyter A; Friedler A
Proc Natl Acad Sci U S A; 2007 May; 104(20):8316-21. PubMed ID: 17488811
[TBL] [Abstract][Full Text] [Related]
6. Small molecule inhibitors of the LEDGF site of human immunodeficiency virus integrase identified by fragment screening and structure based design.
Peat TS; Rhodes DI; Vandegraaff N; Le G; Smith JA; Clark LJ; Jones ED; Coates JA; Thienthong N; Newman J; Dolezal O; Mulder R; Ryan JH; Savage GP; Francis CL; Deadman JJ
PLoS One; 2012; 7(7):e40147. PubMed ID: 22808106
[TBL] [Abstract][Full Text] [Related]
7. Biological and Structural Analyses of New Potent Allosteric Inhibitors of HIV-1 Integrase.
Bonnard D; Le Rouzic E; Singer MR; Yu Z; Le Strat F; Batisse C; Batisse J; Amadori C; Chasset S; Pye VE; Emiliani S; Ledoussal B; Ruff M; Moreau F; Cherepanov P; Benarous R
Antimicrob Agents Chemother; 2023 Jul; 67(7):e0046223. PubMed ID: 37310224
[TBL] [Abstract][Full Text] [Related]
8. Design and synthesis of novel and potent allosteric HIV-1 integrase inhibitors with a spirocyclic moiety.
Adachi K; Manabe T; Yamasaki T; Suma A; Orita T; Furuzono T; Adachi T; Ohata Y; Akiyama Y; Miyazaki S
Bioorg Med Chem Lett; 2024 Jun; ():129864. PubMed ID: 38942126
[TBL] [Abstract][Full Text] [Related]
9. Dihydroxyphenyl- and Heteroaromatic-Based Thienopyrimidinones to Tackle HIV-1 LEDGF/p75-Dependent IN Activity.
Tocco G; Canton S; Laus A; Caboni P; Le Grice SFJ; Tramontano E; Esposito F
Molecules; 2023 Sep; 28(18):. PubMed ID: 37764476
[TBL] [Abstract][Full Text] [Related]
10. Novel PEPPSI-Type NHC Pd(II) Metallosurfactants on the Base of 1H-Imidazole-4,5-dicarboxylic Acid: Synthesis and Catalysis in Water-Organic Media.
Burilov V; Radaev D; Sultanova E; Mironova D; Duglav D; Evtugyn V; Solovieva S; Antipin I
Nanomaterials (Basel); 2022 Nov; 12(22):. PubMed ID: 36432382
[TBL] [Abstract][Full Text] [Related]
11. Studies towards the Design and Synthesis of Novel 1,5-Diaryl-1
Rashamuse TJ; Fish MQ; Coyanis EM; Bode ML
Molecules; 2021 Oct; 26(20):. PubMed ID: 34684786
[TBL] [Abstract][Full Text] [Related]
12. The Hydroxyquinoline Analogue YUM70 Inhibits GRP78 to Induce ER Stress-Mediated Apoptosis in Pancreatic Cancer.
Samanta S; Yang S; Debnath B; Xue D; Kuang Y; Ramkumar K; Lee AS; Ljungman M; Neamati N
Cancer Res; 2021 Apr; 81(7):1883-1895. PubMed ID: 33531374
[TBL] [Abstract][Full Text] [Related]
13. Identification of Inhibitors of Integrin Cytoplasmic Domain Interactions With Syk.
Bakthavatsalam D; Craft JW; Kazansky A; Nguyen N; Bae G; Caivano AR; Gundlach CW; Aslam A; Ali S; Gupta S; Lin SY; Parthiban HD; Vanderslice P; Stephan CC; Woodside DG
Front Immunol; 2020; 11():575085. PubMed ID: 33488575
[TBL] [Abstract][Full Text] [Related]
14. Inhibition of Colon Cancer Cell Growth by Imidazole Through Activation of Apoptotic Pathway.
Long Y; Wang D
Med Sci Monit; 2019 Oct; 25():7597-7604. PubMed ID: 31597910
[TBL] [Abstract][Full Text] [Related]
15. Synthesis and evaluation of imidazole-4,5- and pyrazine-2,3-dicarboxamides targeting dengue and yellow fever virus.
Saudi M; Zmurko J; Kaptein S; Rozenski J; Neyts J; Van Aerschot A
Eur J Med Chem; 2014 Nov; 87():529-39. PubMed ID: 25285371
[TBL] [Abstract][Full Text] [Related]
16. Interrogating HIV integrase for compounds that bind--a SAMPL challenge.
Peat TS; Dolezal O; Newman J; Mobley D; Deadman JJ
J Comput Aided Mol Des; 2014 Apr; 28(4):347-62. PubMed ID: 24532034
[TBL] [Abstract][Full Text] [Related]
17. Discovery of a novel 5-carbonyl-1H-imidazole-4-carboxamide class of inhibitors of the HIV-1 integrase-LEDGF/p75 interaction.
Serrao E; Xu ZL; Debnath B; Christ F; Debyser Z; Long YQ; Neamati N
Bioorg Med Chem; 2013 Oct; 21(19):5963-72. PubMed ID: 23985689
[TBL] [Abstract][Full Text] [Related]
18. The LEDGF/p75 integrase interaction, a novel target for anti-HIV therapy.
Christ F; Debyser Z
Virology; 2013 Jan; 435(1):102-9. PubMed ID: 23217620
[TBL] [Abstract][Full Text] [Related]
19. New scaffolds of natural origin as Integrase-LEDGF/p75 interaction inhibitors: virtual screening and activity assays.
De Luca L; Morreale F; Christ F; Debyser Z; Ferro S; Gitto R
Eur J Med Chem; 2013 Oct; 68():405-11. PubMed ID: 23994868
[TBL] [Abstract][Full Text] [Related]
20.
; ; . PubMed ID:
[No Abstract] [Full Text] [Related]
[Next] [New Search]
