BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

398 related articles for article (PubMed ID: 23986244)

  • 1. Small-fiber neuropathy Nav1.8 mutation shifts activation to hyperpolarized potentials and increases excitability of dorsal root ganglion neurons.
    Huang J; Yang Y; Zhao P; Gerrits MM; Hoeijmakers JG; Bekelaar K; Merkies IS; Faber CG; Dib-Hajj SD; Waxman SG
    J Neurosci; 2013 Aug; 33(35):14087-97. PubMed ID: 23986244
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Increased Resurgent Sodium Currents in Nav1.8 Contribute to Nociceptive Sensory Neuron Hyperexcitability Associated with Peripheral Neuropathies.
    Xiao Y; Barbosa C; Pei Z; Xie W; Strong JA; Zhang JM; Cummins TR
    J Neurosci; 2019 Feb; 39(8):1539-1550. PubMed ID: 30617209
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The G1662S NaV1.8 mutation in small fibre neuropathy: impaired inactivation underlying DRG neuron hyperexcitability.
    Han C; Vasylyev D; Macala LJ; Gerrits MM; Hoeijmakers JG; Bekelaar KJ; Dib-Hajj SD; Faber CG; Merkies IS; Waxman SG
    J Neurol Neurosurg Psychiatry; 2014 May; 85(5):499-505. PubMed ID: 24006052
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The Domain II S4-S5 Linker in Nav1.9: A Missense Mutation Enhances Activation, Impairs Fast Inactivation, and Produces Human Painful Neuropathy.
    Han C; Yang Y; de Greef BT; Hoeijmakers JG; Gerrits MM; Verhamme C; Qu J; Lauria G; Merkies IS; Faber CG; Dib-Hajj SD; Waxman SG
    Neuromolecular Med; 2015 Jun; 17(2):158-69. PubMed ID: 25791876
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Depolarized inactivation overcomes impaired activation to produce DRG neuron hyperexcitability in a Nav1.7 mutation in a patient with distal limb pain.
    Huang J; Yang Y; Dib-Hajj SD; van Es M; Zhao P; Salomon J; Drenth JP; Waxman SG
    J Neurosci; 2014 Sep; 34(37):12328-40. PubMed ID: 25209274
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Differential effect of D623N variant and wild-type Na(v)1.7 sodium channels on resting potential and interspike membrane potential of dorsal root ganglion neurons.
    Ahn HS; Vasylyev DV; Estacion M; Macala LJ; Shah P; Faber CG; Merkies IS; Dib-Hajj SD; Waxman SG
    Brain Res; 2013 Sep; 1529():165-77. PubMed ID: 23850641
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Nav1.7-A1632G Mutation from a Family with Inherited Erythromelalgia: Enhanced Firing of Dorsal Root Ganglia Neurons Evoked by Thermal Stimuli.
    Yang Y; Huang J; Mis MA; Estacion M; Macala L; Shah P; Schulman BR; Horton DB; Dib-Hajj SD; Waxman SG
    J Neurosci; 2016 Jul; 36(28):7511-22. PubMed ID: 27413160
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Gain-of-function mutations in sodium channel Na(v)1.9 in painful neuropathy.
    Huang J; Han C; Estacion M; Vasylyev D; Hoeijmakers JG; Gerrits MM; Tyrrell L; Lauria G; Faber CG; Dib-Hajj SD; Merkies IS; Waxman SG;
    Brain; 2014 Jun; 137(Pt 6):1627-42. PubMed ID: 24776970
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The small fiber neuropathy NaV1.7 I228M mutation: impaired neurite integrity via bioenergetic and mitotoxic mechanisms, and protection by dexpramipexole.
    Lee SI; Hoeijmakers JGJ; Faber CG; Merkies ISJ; Lauria G; Waxman SG
    J Neurophysiol; 2020 Feb; 123(2):645-657. PubMed ID: 31851560
    [TBL] [Abstract][Full Text] [Related]  

  • 10. A novel gain-of-function sodium channel β2 subunit mutation in idiopathic small fiber neuropathy.
    Alsaloum M; Labau JIR; Sosniak D; Zhao P; Almomani R; Gerrits M; Hoeijmakers JGJ; Lauria G; Faber CG; Waxman SG; Dib-Hajj S
    J Neurophysiol; 2021 Sep; 126(3):827-839. PubMed ID: 34320850
    [TBL] [Abstract][Full Text] [Related]  

  • 11. A novel gain-of-function Na
    Adi T; Estacion M; Schulman BR; Vernino S; Dib-Hajj SD; Waxman SG
    Mol Pain; 2018; 14():1744806918815007. PubMed ID: 30392441
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The Novel Activity of Carbamazepine as an Activation Modulator Extends from Na
    Han C; Themistocleous AC; Estacion M; Dib-Hajj FB; Blesneac I; Macala L; Fratter C; Bennett DL; Waxman SG; Dib-Hajj SD
    Mol Pharmacol; 2018 Nov; 94(5):1256-1269. PubMed ID: 30135145
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Na(V)1.7 mutant A863P in erythromelalgia: effects of altered activation and steady-state inactivation on excitability of nociceptive dorsal root ganglion neurons.
    Harty TP; Dib-Hajj SD; Tyrrell L; Blackman R; Hisama FM; Rose JB; Waxman SG
    J Neurosci; 2006 Nov; 26(48):12566-75. PubMed ID: 17135418
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Intra- and interfamily phenotypic diversity in pain syndromes associated with a gain-of-function variant of NaV1.7.
    Estacion M; Han C; Choi JS; Hoeijmakers JG; Lauria G; Drenth JP; Gerrits MM; Dib-Hajj SD; Faber CG; Merkies IS; Waxman SG
    Mol Pain; 2011 Dec; 7():92. PubMed ID: 22136189
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Nav1.7-related small fiber neuropathy: impaired slow-inactivation and DRG neuron hyperexcitability.
    Han C; Hoeijmakers JG; Ahn HS; Zhao P; Shah P; Lauria G; Gerrits MM; te Morsche RH; Dib-Hajj SD; Drenth JP; Faber CG; Merkies IS; Waxman SG
    Neurology; 2012 May; 78(21):1635-43. PubMed ID: 22539570
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Chronic exposure to tumor necrosis factor in vivo induces hyperalgesia, upregulates sodium channel gene expression and alters the cellular electrophysiology of dorsal root ganglion neurons.
    Fischer BD; Ho C; Kuzin I; Bottaro A; O'Leary ME
    Neurosci Lett; 2017 Jul; 653():195-201. PubMed ID: 28558976
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Human Na(v)1.8: enhanced persistent and ramp currents contribute to distinct firing properties of human DRG neurons.
    Han C; Estacion M; Huang J; Vasylyev D; Zhao P; Dib-Hajj SD; Waxman SG
    J Neurophysiol; 2015 May; 113(9):3172-85. PubMed ID: 25787950
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Paroxysmal extreme pain disorder M1627K mutation in human Nav1.7 renders DRG neurons hyperexcitable.
    Dib-Hajj SD; Estacion M; Jarecki BW; Tyrrell L; Fischer TZ; Lawden M; Cummins TR; Waxman SG
    Mol Pain; 2008 Sep; 4():37. PubMed ID: 18803825
    [TBL] [Abstract][Full Text] [Related]  

  • 19. I
    Vasylyev DV; Liu S; Waxman SG
    J Physiol; 2023 Dec; 601(23):5341-5366. PubMed ID: 37846879
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Functional profiles of SCN9A variants in dorsal root ganglion neurons and superior cervical ganglion neurons correlate with autonomic symptoms in small fibre neuropathy.
    Han C; Hoeijmakers JG; Liu S; Gerrits MM; te Morsche RH; Lauria G; Dib-Hajj SD; Drenth JP; Faber CG; Merkies IS; Waxman SG
    Brain; 2012 Sep; 135(Pt 9):2613-28. PubMed ID: 22826602
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 20.