BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

542 related articles for article (PubMed ID: 23988329)

  • 1. Previously unknown role for the ubiquitin ligase Ubr1 in endoplasmic reticulum-associated protein degradation.
    Stolz A; Besser S; Hottmann H; Wolf DH
    Proc Natl Acad Sci U S A; 2013 Sep; 110(38):15271-6. PubMed ID: 23988329
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Endoplasmic Reticulum-associated Degradation of Pca1p, a Polytopic Protein, via Interaction with the Proteasome at the Membrane.
    Smith N; Adle DJ; Zhao M; Qin X; Kim H; Lee J
    J Biol Chem; 2016 Jul; 291(29):15082-92. PubMed ID: 27226596
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Assays to measure ER-associated degradation in yeast.
    Tran JR; Brodsky JL
    Methods Mol Biol; 2012; 832():505-18. PubMed ID: 22350909
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Autoubiquitination of the Hrd1 Ligase Triggers Protein Retrotranslocation in ERAD.
    Baldridge RD; Rapoport TA
    Cell; 2016 Jul; 166(2):394-407. PubMed ID: 27321670
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Hsp70 targets a cytoplasmic quality control substrate to the San1p ubiquitin ligase.
    Guerriero CJ; Weiberth KF; Brodsky JL
    J Biol Chem; 2013 Jun; 288(25):18506-20. PubMed ID: 23653356
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Degradation Signals for Ubiquitin-Proteasome Dependent Cytosolic Protein Quality Control (CytoQC) in Yeast.
    Maurer MJ; Spear ED; Yu AT; Lee EJ; Shahzad S; Michaelis S
    G3 (Bethesda); 2016 Jul; 6(7):1853-66. PubMed ID: 27172186
    [TBL] [Abstract][Full Text] [Related]  

  • 7. A Cdc48 "Retrochaperone" Function Is Required for the Solubility of Retrotranslocated, Integral Membrane Endoplasmic Reticulum-associated Degradation (ERAD-M) Substrates.
    Neal S; Mak R; Bennett EJ; Hampton R
    J Biol Chem; 2017 Feb; 292(8):3112-3128. PubMed ID: 28077573
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The Type II Hsp40 Sis1 cooperates with Hsp70 and the E3 ligase Ubr1 to promote degradation of terminally misfolded cytosolic protein.
    Summers DW; Wolfe KJ; Ren HY; Cyr DM
    PLoS One; 2013; 8(1):e52099. PubMed ID: 23341891
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The Dfm1 Derlin Is Required for ERAD Retrotranslocation of Integral Membrane Proteins.
    Neal S; Jaeger PA; Duttke SH; Benner C; K Glass C; Ideker T; Hampton RY
    Mol Cell; 2018 Jan; 69(2):306-320.e4. PubMed ID: 29351849
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Dfm1 forms distinct complexes with Cdc48 and the ER ubiquitin ligases and is required for ERAD.
    Stolz A; Schweizer RS; Schäfer A; Wolf DH
    Traffic; 2010 Oct; 11(10):1363-9. PubMed ID: 20579315
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Membrane-bound Ubx2 recruits Cdc48 to ubiquitin ligases and their substrates to ensure efficient ER-associated protein degradation.
    Schuberth C; Buchberger A
    Nat Cell Biol; 2005 Oct; 7(10):999-1006. PubMed ID: 16179952
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Degradation of integral membrane proteins modified with the photosensitive degron module requires the cytosolic endoplasmic reticulum-associated degradation pathway.
    Scheffer J; Hasenjäger S; Taxis C
    Mol Biol Cell; 2019 Sep; 30(20):2558-2570. PubMed ID: 31411939
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Distinct machinery is required in Saccharomyces cerevisiae for the endoplasmic reticulum-associated degradation of a multispanning membrane protein and a soluble luminal protein.
    Huyer G; Piluek WF; Fansler Z; Kreft SG; Hochstrasser M; Brodsky JL; Michaelis S
    J Biol Chem; 2004 Sep; 279(37):38369-78. PubMed ID: 15252059
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Ubx2 links the Cdc48 complex to ER-associated protein degradation.
    Neuber O; Jarosch E; Volkwein C; Walter J; Sommer T
    Nat Cell Biol; 2005 Oct; 7(10):993-8. PubMed ID: 16179953
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Subcellular Fractionation Analysis of the Extraction of Ubiquitinated Polytopic Membrane Substrate during ER-Associated Degradation.
    Nakatsukasa K; Kamura T
    PLoS One; 2016; 11(2):e0148327. PubMed ID: 26849222
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Ubiquitin ligase Hul5 is required for fragment-specific substrate degradation in endoplasmic reticulum-associated degradation.
    Kohlmann S; Schäfer A; Wolf DH
    J Biol Chem; 2008 Jun; 283(24):16374-83. PubMed ID: 18436532
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Key steps in ERAD of luminal ER proteins reconstituted with purified components.
    Stein A; Ruggiano A; Carvalho P; Rapoport TA
    Cell; 2014 Sep; 158(6):1375-1388. PubMed ID: 25215493
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Dissecting the ER-associated degradation of a misfolded polytopic membrane protein.
    Nakatsukasa K; Huyer G; Michaelis S; Brodsky JL
    Cell; 2008 Jan; 132(1):101-12. PubMed ID: 18191224
    [TBL] [Abstract][Full Text] [Related]  

  • 19. A stalled retrotranslocation complex reveals physical linkage between substrate recognition and proteasomal degradation during ER-associated degradation.
    Nakatsukasa K; Brodsky JL; Kamura T
    Mol Biol Cell; 2013 Jun; 24(11):1765-75, S1-8. PubMed ID: 23536702
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Ubx4 modulates cdc48 activity and influences degradation of misfolded proteins of the endoplasmic reticulum.
    Alberts SM; Sonntag C; Schäfer A; Wolf DH
    J Biol Chem; 2009 Jun; 284(24):16082-16089. PubMed ID: 19359248
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 28.