BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

422 related articles for article (PubMed ID: 23988911)

  • 1. p27kip1 maintains a subset of leukemia stem cells in the quiescent state in murine MLL-leukemia.
    Zhang J; Seet CS; Sun C; Li J; You D; Volk A; Breslin P; Li X; Wei W; Qian Z; Zeleznik-Le NJ; Zhang Z; Zhang J
    Mol Oncol; 2013 Dec; 7(6):1069-82. PubMed ID: 23988911
    [TBL] [Abstract][Full Text] [Related]  

  • 2. PBX3 and MEIS1 Cooperate in Hematopoietic Cells to Drive Acute Myeloid Leukemias Characterized by a Core Transcriptome of the MLL-Rearranged Disease.
    Li Z; Chen P; Su R; Hu C; Li Y; Elkahloun AG; Zuo Z; Gurbuxani S; Arnovitz S; Weng H; Wang Y; Li S; Huang H; Neilly MB; Wang GG; Jiang X; Liu PP; Jin J; Chen J
    Cancer Res; 2016 Feb; 76(3):619-29. PubMed ID: 26747896
    [TBL] [Abstract][Full Text] [Related]  

  • 3. PBX3 is essential for leukemia stem cell maintenance in MLL-rearranged leukemia.
    Guo H; Chu Y; Wang L; Chen X; Chen Y; Cheng H; Zhang L; Zhou Y; Yang FC; Cheng T; Xu M; Zhang X; Zhou J; Yuan W
    Int J Cancer; 2017 Jul; 141(2):324-335. PubMed ID: 28411381
    [TBL] [Abstract][Full Text] [Related]  

  • 4. CD93 Marks a Non-Quiescent Human Leukemia Stem Cell Population and Is Required for Development of MLL-Rearranged Acute Myeloid Leukemia.
    Iwasaki M; Liedtke M; Gentles AJ; Cleary ML
    Cell Stem Cell; 2015 Oct; 17(4):412-21. PubMed ID: 26387756
    [TBL] [Abstract][Full Text] [Related]  

  • 5. PU.1 is essential for MLL leukemia partially via crosstalk with the MEIS/HOX pathway.
    Zhou J; Wu J; Li B; Liu D; Yu J; Yan X; Zheng S; Wang J; Zhang L; Zhang L; He F; Li Q; Chen A; Zhang Y; Zhao X; Guan Y; Zhao X; Yan J; Ni J; Nobrega MA; Löwenberg B; Delwel R; Valk PJ; Kumar A; Xie L; Tenen DG; Huang G; Wang QF
    Leukemia; 2014 Jul; 28(7):1436-48. PubMed ID: 24445817
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Meis1 is an essential and rate-limiting regulator of MLL leukemia stem cell potential.
    Wong P; Iwasaki M; Somervaille TC; So CW; Cleary ML
    Genes Dev; 2007 Nov; 21(21):2762-74. PubMed ID: 17942707
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Upregulation of Flt3 is a passive event in Hoxa9/Meis1-induced acute myeloid leukemia in mice.
    Staffas A; Arabanian LS; Wei SY; Jansson A; Ståhlman S; Johansson P; Fogelstrand L; Cammenga J; Kuchenbauer F; Palmqvist L
    Oncogene; 2017 Mar; 36(11):1516-1524. PubMed ID: 27617578
    [TBL] [Abstract][Full Text] [Related]  

  • 8. A Multiplex CRISPR-Screen Identifies PLA2G4A as Prognostic Marker and Druggable Target for HOXA9 and MEIS1 Dependent AML.
    Hassan JJ; Lieske A; Dörpmund N; Klatt D; Hoffmann D; Kleppa MJ; Kustikova OS; Stahlhut M; Schwarzer A; Schambach A; Maetzig T
    Int J Mol Sci; 2021 Aug; 22(17):. PubMed ID: 34502319
    [No Abstract]   [Full Text] [Related]  

  • 9. MLL fusion protein-driven AML is selectively inhibited by targeted disruption of the MLL-PAFc interaction.
    Muntean AG; Chen W; Jones M; Granowicz EM; Maillard I; Hess JL
    Blood; 2013 Sep; 122(11):1914-22. PubMed ID: 23900238
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Flt3 is dispensable to the Hoxa9/Meis1 leukemogenic cooperation.
    Morgado E; Albouhair S; Lavau C
    Blood; 2007 May; 109(9):4020-2. PubMed ID: 17202314
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Hif-1α and Hif-2α synergize to suppress AML development but are dispensable for disease maintenance.
    Vukovic M; Guitart AV; Sepulveda C; Villacreces A; O'Duibhir E; Panagopoulou TI; Ivens A; Menendez-Gonzalez J; Iglesias JM; Allen L; Glykofrydis F; Subramani C; Armesilla-Diaz A; Post AE; Schaak K; Gezer D; So CW; Holyoake TL; Wood A; O'Carroll D; Ratcliffe PJ; Kranc KR
    J Exp Med; 2015 Dec; 212(13):2223-34. PubMed ID: 26642852
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Myc-Miz1 signaling promotes self-renewal of leukemia stem cells by repressing Cebpα and Cebpδ.
    Zhang L; Li J; Xu H; Shao X; Fu L; Hou Y; Hao C; Li W; Joshi K; Wei W; Xu Y; Zhang F; Dai S; Breslin P; Zhang J; Zhang J
    Blood; 2020 Apr; 135(14):1133-1145. PubMed ID: 32040550
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Heritable genetic background alters survival and phenotype of Mll-AF9-induced leukemias.
    Young K; Loberg MA; Eudy E; Schwartz LS; Mujica KD; Trowbridge JJ
    Exp Hematol; 2020 Sep; 89():61-67.e3. PubMed ID: 32768438
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Persistent transactivation by meis1 replaces hox function in myeloid leukemogenesis models: evidence for co-occupancy of meis1-pbx and hox-pbx complexes on promoters of leukemia-associated genes.
    Wang GG; Pasillas MP; Kamps MP
    Mol Cell Biol; 2006 May; 26(10):3902-16. PubMed ID: 16648484
    [TBL] [Abstract][Full Text] [Related]  

  • 15. MiR-495 is a tumor-suppressor microRNA down-regulated in MLL-rearranged leukemia.
    Jiang X; Huang H; Li Z; He C; Li Y; Chen P; Gurbuxani S; Arnovitz S; Hong GM; Price C; Ren H; Kunjamma RB; Neilly MB; Salat J; Wunderlich M; Slany RK; Zhang Y; Larson RA; Le Beau MM; Mulloy JC; Rowley JD; Chen J
    Proc Natl Acad Sci U S A; 2012 Nov; 109(47):19397-402. PubMed ID: 23132946
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Expression of HOX genes, HOX cofactors, and MLL in phenotypically and functionally defined subpopulations of leukemic and normal human hematopoietic cells.
    Kawagoe H; Humphries RK; Blair A; Sutherland HJ; Hogge DE
    Leukemia; 1999 May; 13(5):687-98. PubMed ID: 10374871
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The AAA+ ATPase RUVBL2 is a critical mediator of MLL-AF9 oncogenesis.
    Osaki H; Walf-Vorderwülbecke V; Mangolini M; Zhao L; Horton SJ; Morrone G; Schuringa JJ; de Boer J; Williams O
    Leukemia; 2013 Jul; 27(7):1461-8. PubMed ID: 23403462
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Transcriptional memory of cells of origin overrides β-catenin requirement of MLL cancer stem cells.
    Siriboonpiputtana T; Zeisig BB; Zarowiecki M; Fung TK; Mallardo M; Tsai CT; Lau PNI; Hoang QC; Veiga P; Barnes J; Lynn C; Wilson A; Lenhard B; So CWE
    EMBO J; 2017 Nov; 36(21):3139-3155. PubMed ID: 28978671
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Linkage of the potent leukemogenic activity of Meis1 to cell-cycle entry and transcriptional regulation of cyclin D3.
    Argiropoulos B; Yung E; Xiang P; Lo CY; Kuchenbauer F; Palmqvist L; Reindl C; Heuser M; Sekulovic S; Rosten P; Muranyi A; Goh SL; Featherstone M; Humphries RK
    Blood; 2010 May; 115(20):4071-82. PubMed ID: 20237320
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Inhibition of histone methyltransferase EZH2 depletes leukemia stem cell of mixed lineage leukemia fusion leukemia through upregulation of p16.
    Ueda K; Yoshimi A; Kagoya Y; Nishikawa S; Marquez VE; Nakagawa M; Kurokawa M
    Cancer Sci; 2014 May; 105(5):512-9. PubMed ID: 24612037
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 22.