BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

241 related articles for article (PubMed ID: 23993461)

  • 1. Probing the selectivity and protein·protein interactions of a nonreducing fungal polyketide synthase using mechanism-based crosslinkers.
    Bruegger J; Haushalter RW; Vagstad AL; Shakya G; Mih N; Townsend CA; Burkart MD; Tsai SC
    Chem Biol; 2013 Sep; 20(9):1135-46. PubMed ID: 23993461
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Structural basis for selectivity in a highly reducing type II polyketide synthase.
    Du D; Katsuyama Y; Horiuchi M; Fushinobu S; Chen A; Davis TD; Burkart MD; Ohnishi Y
    Nat Chem Biol; 2020 Jul; 16(7):776-782. PubMed ID: 32367018
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Structural and Biochemical Analysis of Protein-Protein Interactions Between the Acyl-Carrier Protein and Product Template Domain.
    Barajas JF; Finzel K; Valentic TR; Shakya G; Gamarra N; Martinez D; Meier JL; Vagstad AL; Newman AG; Townsend CA; Burkart MD; Tsai SC
    Angew Chem Int Ed Engl; 2016 Oct; 55(42):13005-13009. PubMed ID: 27653519
    [TBL] [Abstract][Full Text] [Related]  

  • 4. A photocrosslinking assay for reporting protein interactions in polyketide and fatty acid synthases.
    Ye Z; Bair M; Desai H; Williams GJ
    Mol Biosyst; 2011 Nov; 7(11):3152-6. PubMed ID: 21918773
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Insights into modular polyketide synthase loops aided by repetitive sequences.
    Hirsch M; Kumru K; Desai RR; Fitzgerald BJ; Miyazawa T; Ray KA; Saif N; Spears S; Keatinge-Clay AT
    Proteins; 2021 Sep; 89(9):1099-1110. PubMed ID: 33843112
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Starter unit flexibility for engineered product synthesis by the nonreducing polyketide synthase PksA.
    Huitt-Roehl CR; Hill EA; Adams MM; Vagstad AL; Li JW; Townsend CA
    ACS Chem Biol; 2015 Jun; 10(6):1443-9. PubMed ID: 25714897
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Identification of a starter unit acyl-carrier protein transacylase domain in an iterative type I polyketide synthase.
    Crawford JM; Dancy BC; Hill EA; Udwary DW; Townsend CA
    Proc Natl Acad Sci U S A; 2006 Nov; 103(45):16728-33. PubMed ID: 17071746
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Prediction of inter domain interactions in modular polyketide synthases by docking and correlated mutation analysis.
    Yadav G; Anand S; Mohanty D
    J Biomol Struct Dyn; 2013; 31(1):17-29. PubMed ID: 22803697
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The structural organization of substrate loading in iterative polyketide synthases.
    Herbst DA; Huitt-Roehl CR; Jakob RP; Kravetz JM; Storm PA; Alley JR; Townsend CA; Maier T
    Nat Chem Biol; 2018 May; 14(5):474-479. PubMed ID: 29610486
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Probing the structure and function of acyl carrier proteins to unlock the strategic redesign of type II polyketide biosynthetic pathways.
    Sulpizio A; Crawford CEW; Koweek RS; Charkoudian LK
    J Biol Chem; 2021; 296():100328. PubMed ID: 33493513
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Mechanism based protein crosslinking of domains from the 6-deoxyerythronolide B synthase.
    Kapur S; Worthington A; Tang Y; Cane DE; Burkart MD; Khosla C
    Bioorg Med Chem Lett; 2008 May; 18(10):3034-8. PubMed ID: 18243693
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Evidence for a protein-protein interaction motif on an acyl carrier protein domain from a modular polyketide synthase.
    Weissman KJ; Hong H; Popovic B; Meersman F
    Chem Biol; 2006 Jun; 13(6):625-36. PubMed ID: 16793520
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Ketosynthases in the initiation and elongation modules of aromatic polyketide synthases have orthogonal acyl carrier protein specificity.
    Tang Y; Lee TS; Kobayashi S; Khosla C
    Biochemistry; 2003 Jun; 42(21):6588-95. PubMed ID: 12767243
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Extender unit and acyl carrier protein specificity of ketosynthase domains of the 6-deoxyerythronolide B synthase.
    Chen AY; Schnarr NA; Kim CY; Cane DE; Khosla C
    J Am Chem Soc; 2006 Mar; 128(9):3067-74. PubMed ID: 16506788
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Molecular recognition between ketosynthase and acyl carrier protein domains of the 6-deoxyerythronolide B synthase.
    Kapur S; Chen AY; Cane DE; Khosla C
    Proc Natl Acad Sci U S A; 2010 Dec; 107(51):22066-71. PubMed ID: 21127271
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Structural visualization of transient interactions between the cis-acting acyltransferase and acyl carrier protein of the salinomycin modular polyketide synthase.
    Feng Y; Zhang F; Huang S; Deng Z; Bai L; Zheng J
    Acta Crystallogr D Struct Biol; 2022 Jun; 78(Pt 6):779-791. PubMed ID: 35647924
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Structural snapshots of the minimal PKS system responsible for octaketide biosynthesis.
    Bräuer A; Zhou Q; Grammbitter GLC; Schmalhofer M; Rühl M; Kaila VRI; Bode HB; Groll M
    Nat Chem; 2020 Aug; 12(8):755-763. PubMed ID: 32632186
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Probing the interactions of an acyl carrier protein domain from the 6-deoxyerythronolide B synthase.
    Charkoudian LK; Liu CW; Capone S; Kapur S; Cane DE; Togni A; Seebach D; Khosla C
    Protein Sci; 2011 Jul; 20(7):1244-55. PubMed ID: 21563224
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Characterization of the Ketosynthase and Acyl Carrier Protein Domains at the LnmI Nonribosomal Peptide Synthetase-Polyketide Synthase Interface for Leinamycin Biosynthesis.
    Huang Y; Tang GL; Pan G; Chang CY; Shen B
    Org Lett; 2016 Sep; 18(17):4288-91. PubMed ID: 27541042
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Preliminary kinetic analysis of acyl carrier protein-ketoacylsynthase interactions in the actinorhodin minimal polyketide synthase.
    Beltran-Alvarez P; Arthur CJ; Cox RJ; Crosby J; Crump MP; Simpson TJ
    Mol Biosyst; 2009 May; 5(5):511-8. PubMed ID: 19381365
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.