BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

148 related articles for article (PubMed ID: 23994325)

  • 1. Epothilone D and its 9-Methyl analogues: combinatorial syntheses, conformation, and biological activities.
    Sang F; Feng P; Chen J; Ding Y; Duan X; Zhai J; Ma X; Zhang B; Zhang Q; Lin J; Chen Y
    Eur J Med Chem; 2013 Oct; 68():321-32. PubMed ID: 23994325
    [TBL] [Abstract][Full Text] [Related]  

  • 2. C-15 thiazol-4-yl analogues of (E)-9,10-didehydroepothilone D: synthesis and cytotoxicity.
    Hearn BR; Zhang D; Li Y; Myles DC
    Org Lett; 2006 Jul; 8(14):3057-9. PubMed ID: 16805551
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Conformation-activity relationships in polyketide natural products: a new perspective on the rational design of epothilone analogues.
    Taylor RE; Chen Y; Beatty A; Myles DC; Zhou Y
    J Am Chem Soc; 2003 Jan; 125(1):26-7. PubMed ID: 12515494
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Design, synthesis and biological evaluation of bridged epothilone D analogues.
    Chen QH; Ganesh T; Brodie P; Slebodnick C; Jiang Y; Banerjee A; Bane S; Snyder JP; Kingston DG
    Org Biomol Chem; 2008 Dec; 6(24):4542-52. PubMed ID: 19039362
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Design, total synthesis, and evaluation of novel open-chain epothilone analogues.
    Alhamadsheh MM; Hudson RA; Viranga Tillekeratne LM
    Org Lett; 2006 Feb; 8(4):685-8. PubMed ID: 16468742
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Epothilone analogues with benzimidazole and quinoline side chains: chemical synthesis, antiproliferative activity, and interactions with tubulin.
    Dietrich SA; Lindauer R; Stierlin C; Gertsch J; Matesanz R; Notararigo S; Díaz JF; Altmann KH
    Chemistry; 2009 Oct; 15(39):10144-57. PubMed ID: 19697384
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Design, synthesis, and biological properties of highly potent epothilone B analogues.
    Nicolaou KC; Sasmal PK; Rassias G; Reddy MV; Altmann KH; Wartmann M; O'Brate A; Giannakakou P
    Angew Chem Int Ed Engl; 2003 Aug; 42(30):3515-20. PubMed ID: 12900969
    [No Abstract]   [Full Text] [Related]  

  • 8. Synthesis and conformational analysis of (E)-9,10-dehydroepothilone B: a suggestive link between the chemistry and biology of epothilones.
    Yoshimura F; Rivkin A; Gabarda AE; Chou TC; Dong H; Sukenick G; Morel FF; Taylor RE; Danishefsky SJ
    Angew Chem Int Ed Engl; 2003 Jun; 42(22):2518-21. PubMed ID: 12800175
    [No Abstract]   [Full Text] [Related]  

  • 9. Total syntheses of [17]- and [18]dehydrodesoxyepothilones B via a concise ring-closing metathesis-based strategy: correlation of ring size with biological activity in the epothilone series.
    Rivkin A; Njardarson JT; Biswas K; Chou TC; Danishefsky SJ
    J Org Chem; 2002 Nov; 67(22):7737-40. PubMed ID: 12398497
    [TBL] [Abstract][Full Text] [Related]  

  • 10. C6-C8 bridged epothilones: consequences of installing a conformational lock at the edge of the macrocycle.
    Zhan W; Jiang Y; Sharma S; Brodie PJ; Bane S; Kingston DG; Liotta DC; Snyder JP
    Chemistry; 2011 Dec; 17(52):14792-804. PubMed ID: 22127984
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Total synthesis and biological assessment of benzimidazole-based analogues of epothilone A: ambivalent effects on cancer cell growth inhibition.
    Cachoux F; Isarno T; Wartmann M; Altmann KH
    Chembiochem; 2006 Jan; 7(1):54-7. PubMed ID: 16345113
    [No Abstract]   [Full Text] [Related]  

  • 12. Synthesis and Biological Evaluation of 7-Deoxy-Epothilone Analogues.
    Woods LM; Arico JW; Frein JD; Sackett DL; Taylor RE
    Int J Mol Sci; 2017 Mar; 18(3):. PubMed ID: 28304361
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Design, synthesis, and biological evaluation of artificial macrosphelides in the search for new apoptosis-inducing agents.
    Matsuya Y; Kobayashi Y; Kawaguchi T; Hori A; Watanabe Y; Ishihara K; Ahmed K; Wei ZL; Yu DY; Zhao QL; Kondo T; Nemoto H
    Chemistry; 2009 Jun; 15(23):5799-813. PubMed ID: 19370747
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Complex target-oriented total synthesis in the drug discovery process: the discovery of a highly promising family of second generation epothilones.
    Rivkin A; Yoshimura F; Gabarda AE; Chou TC; Dong H; Tong WP; Danishefsky SJ
    J Am Chem Soc; 2003 Mar; 125(10):2899-901. PubMed ID: 12617656
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Synthesis and antitumor activity of epothilone B.
    Cheng H; Huang H; Huang G
    Eur J Med Chem; 2018 Sep; 157():925-934. PubMed ID: 30149324
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Synthesis & antitumor activity of epothilones B and D and their analogs.
    Cheng H; Huang G
    Future Med Chem; 2018 Jun; 10(12):1483-1496. PubMed ID: 29788770
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Isolation and characterization of new epothilone analogues from recombinant Myxococcus xanthus fermentations.
    Starks CM; Zhou Y; Liu F; Licari PJ
    J Nat Prod; 2003 Oct; 66(10):1313-7. PubMed ID: 14575429
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Total synthesis and selective activity of a new class of conformationally restrained epothilones.
    Alhamadsheh MM; Gupta S; Hudson RA; Perera L; Tillekeratne LM
    Chemistry; 2008; 14(2):570-81. PubMed ID: 17955508
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Five new epothilone metabolites from Sorangium cellulosum strain So0157-2.
    Wang J; Zhang H; Ying L; Wang C; Jiang N; Zhou Y; Wang H; Bai H
    J Antibiot (Tokyo); 2009 Sep; 62(9):483-7. PubMed ID: 19575038
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The epothilones and related analogues-a review of their syntheses and anti-cancer activities.
    Watkins EB; Chittiboyina AG; Jung JC; Avery MA
    Curr Pharm Des; 2005; 11(13):1615-53. PubMed ID: 15892666
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.