BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

282 related articles for article (PubMed ID: 23994871)

  • 1. New platinum(II) complexes conjugated at position 7α of 17β-acetyl-testosterone as new combi-molecules against prostate cancer: design, synthesis, structure-activity relationships and biological evaluation.
    Fortin S; Brasseur K; Morin N; Asselin É; Bérubé G
    Eur J Med Chem; 2013 Oct; 68():433-43. PubMed ID: 23994871
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Second-generation testosterone-platinum(II) hybrids for site-specific treatment of androgen receptor positive prostate cancer: Design, synthesis and antiproliferative activity.
    Ouellette V; Côté MF; Gaudreault RC; Tajmir-Riahi HA; Bérubé G
    Eur J Med Chem; 2019 Oct; 179():660-666. PubMed ID: 31279298
    [TBL] [Abstract][Full Text] [Related]  

  • 3. New testosterone derivatives as semi-synthetic anticancer agents against prostate cancer: synthesis and preliminary biological evaluation.
    Morin N; Bruneau J; Fortin S; Brasseur K; Leblanc V; Asselin E; Berube G
    Med Chem; 2015; 11(6):531-9. PubMed ID: 25675439
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Synthesis and preliminary in vitro biological evaluation of 7α-testosterone-chlorambucil hybrid designed for the treatment of prostate cancer.
    Bastien D; Hanna R; Leblanc V; Asselin É; Bérubé G
    Eur J Med Chem; 2013 Jun; 64():442-7. PubMed ID: 23665800
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Novel platinum(II) complexes of 3-(aminomethyl)naphthoquinone Mannich bases: synthesis, crystal structure and cytotoxic activities.
    Neves AP; da Silva GB; Vargas MD; Pinheiro CB; Visentin Ldo C; Filho JD; Araújo AJ; Costa-Lotufo LV; Pessoa C; de Moraes MO
    Dalton Trans; 2010 Nov; 39(42):10203-16. PubMed ID: 20871881
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Design, synthesis and biological evaluation of estradiol-PEG-linked platinum(II) hybrid molecules: comparative molecular modeling study of three distinct families of hybrids.
    Provencher-Mandeville J; Debnath C; Mandal SK; Leblanc V; Parent S; Asselin E; Bérubé G
    Steroids; 2011 Jan; 76(1-2):94-103. PubMed ID: 20869376
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Antiproliferative, antiandrogenic and cytotoxic effects of novel caffeic acid derivatives in LNCaP human androgen-dependent prostate cancer cells.
    Sanderson JT; Clabault H; Patton C; Lassalle-Claux G; Jean-François J; Paré AF; Hébert MJ; Surette ME; Touaibia M
    Bioorg Med Chem; 2013 Nov; 21(22):7182-93. PubMed ID: 24080105
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Niphatenones, glycerol ethers from the sponge Niphates digitalis block androgen receptor transcriptional activity in prostate cancer cells: structure elucidation, synthesis, and biological activity.
    Meimetis LG; Williams DE; Mawji NR; Banuelos CA; Lal AA; Park JJ; Tien AH; Fernandez JG; de Voogd NJ; Sadar MD; Andersen RJ
    J Med Chem; 2012 Jan; 55(1):503-14. PubMed ID: 22148427
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Platinum(II) complexes containing aminophosphonate esters: Synthesis, characterization, cytotoxicity and action mechanism.
    Huang KB; Chen ZF; Liu YC; Li ZQ; Wei JH; Wang M; Xie XL; Liang H
    Eur J Med Chem; 2013 Jun; 64():554-61. PubMed ID: 23685573
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Synthesis, antiproliferative activity and estrogen receptor α affinity of novel estradiol-linked platinum(II) complex analogs to carboplatin and oxaliplatin. Potential vector complexes to target estrogen-dependent tissues.
    Saha P; Descôteaux C; Brasseur K; Fortin S; Leblanc V; Parent S; Asselin E; Bérubé G
    Eur J Med Chem; 2012 Feb; 48():385-90. PubMed ID: 22209414
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Development of hormone-dependent prostate cancer models for the evaluation of inhibitors of 17beta-hydroxysteroid dehydrogenase type 3.
    Day JM; Tutill HJ; Foster PA; Bailey HV; Heaton WB; Sharland CM; Vicker N; Potter BV; Purohit A; Reed MJ
    Mol Cell Endocrinol; 2009 Mar; 301(1-2):251-8. PubMed ID: 18786604
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Studies of the mechanism of action of platinum(II) complexes with potent cytotoxicity in human cancer cells.
    Krause-Heuer AM; Grünert R; Kühne S; Buczkowska M; Wheate NJ; Le Pevelen DD; Boag LR; Fisher DM; Kasparkova J; Malina J; Bednarski PJ; Brabec V; Aldrich-Wright JR
    J Med Chem; 2009 Sep; 52(17):5474-84. PubMed ID: 19658404
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Potential new antitumor agents from an innovative combination of camphorato, a ramification of traditional Chinese medicine, with a platinum moiety.
    Wang L; Gou S; Chen Y; Liu Y
    Bioorg Med Chem Lett; 2005 Jul; 15(14):3417-22. PubMed ID: 15953727
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Antitumor activity of phenylene bridged binuclear bis(imino-quinolyl)palladium(II) and platinum(II) complexes.
    Motswainyana WM; Onani MO; Madiehe AM; Saibu M
    Bioorg Med Chem Lett; 2014 Apr; 24(7):1692-4. PubMed ID: 24636106
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Design, modeling, synthesis and biological activity evaluation of camptothecin-linked platinum anticancer agents.
    Cincinelli R; Musso L; Dallavalle S; Artali R; Tinelli S; Colangelo D; Zunino F; De Cesare M; Beretta GL; Zaffaroni N
    Eur J Med Chem; 2013 May; 63():387-400. PubMed ID: 23517728
    [TBL] [Abstract][Full Text] [Related]  

  • 16. In vitro biological evaluation of platinum(II) complexes with 1-(methoxy substituted benzyl) azetidine-3,3-dicarboxylato ligands.
    Yin R; Gou S; Sun Y; Liu X
    Bioorg Med Chem; 2012 Feb; 20(4):1461-7. PubMed ID: 22264764
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Carbidopa enhances antitumoral activity of bicalutamide on the androgen receptor-axis in castration-resistant prostate tumors.
    Thomas C; Wafa LA; Lamoureux F; Cheng H; Fazli L; Gleave ME; Rennie PS
    Prostate; 2012 Jun; 72(8):875-85. PubMed ID: 22072572
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Novel platinum(II) compounds with O,S bidentate ligands: synthesis, characterization, antiproliferative properties and biomolecular interactions.
    Mügge C; Liu R; Görls H; Gabbiani C; Michelucci E; Rüdiger N; Clement JH; Messori L; Weigand W
    Dalton Trans; 2014 Feb; 43(8):3072-86. PubMed ID: 24169734
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Evaluation of in vitro cytotoxicity and hepatotoxicity of platinum(II) and palladium(II) oxalato complexes with adenine derivatives as carrier ligands.
    Vrzal R; Starha P; Dvorák Z; Trávnícek Z
    J Inorg Biochem; 2010 Oct; 104(10):1130-2. PubMed ID: 20673688
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Identification of EP4 as a potential target for the treatment of castration-resistant prostate cancer using a novel xenograft model.
    Terada N; Shimizu Y; Kamba T; Inoue T; Maeno A; Kobayashi T; Nakamura E; Kamoto T; Kanaji T; Maruyama T; Mikami Y; Toda Y; Matsuoka T; Okuno Y; Tsujimoto G; Narumiya S; Ogawa O
    Cancer Res; 2010 Feb; 70(4):1606-15. PubMed ID: 20145136
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.