145 related articles for article (PubMed ID: 23995353)
1. Medicinal chemistry and chemical biology of diketopiperazine-type antimicrotubule and vascular-disrupting agents.
Hayashi Y; Yamazaki-Nakamura Y; Yakushiji F
Chem Pharm Bull (Tokyo); 2013; 61(9):889-901. PubMed ID: 23995353
[TBL] [Abstract][Full Text] [Related]
2. Tubulin photoaffinity labeling with biotin-tagged derivatives of potent diketopiperazine antimicrotubule agents.
Yamazaki Y; Kohno K; Yasui H; Kiso Y; Akamatsu M; Nicholson B; Deyanat-Yazdi G; Neuteboom S; Potts B; Lloyd GK; Hayashi Y
Chembiochem; 2008 Dec; 9(18):3074-81. PubMed ID: 19012291
[TBL] [Abstract][Full Text] [Related]
3. Synthesis and structure-activity relationship study of antimicrotubule agents phenylahistin derivatives with a didehydropiperazine-2,5-dione structure.
Yamazaki Y; Tanaka K; Nicholson B; Deyanat-Yazdi G; Potts B; Yoshida T; Oda A; Kitagawa T; Orikasa S; Kiso Y; Yasui H; Akamatsu M; Chinen T; Usui T; Shinozaki Y; Yakushiji F; Miller BR; Neuteboom S; Palladino M; Kanoh K; Lloyd GK; Hayashi Y
J Med Chem; 2012 Feb; 55(3):1056-71. PubMed ID: 22185476
[TBL] [Abstract][Full Text] [Related]
4. Synthesis and structure-activity relationships of benzophenone-bearing diketopiperazine-type anti-microtubule agents.
Yamazaki Y; Sumikura M; Masuda Y; Hayashi Y; Yasui H; Kiso Y; Chinen T; Usui T; Yakushiji F; Potts B; Neuteboom S; Palladino M; Lloyd GK; Hayashi Y
Bioorg Med Chem; 2012 Jul; 20(14):4279-89. PubMed ID: 22727370
[TBL] [Abstract][Full Text] [Related]
5. Tubulin photoaffinity labeling study with a plinabulin chemical probe possessing a biotin tag at the oxazole.
Yamazaki Y; Kido Y; Hidaka K; Yasui H; Kiso Y; Yakushiji F; Hayashi Y
Bioorg Med Chem; 2011 Jan; 19(1):595-602. PubMed ID: 21106379
[TBL] [Abstract][Full Text] [Related]
6. Development of novel phenoxy-diketopiperazine-type plinabulin derivatives as potent antimicrotubule agents based on the co-crystal structure.
Ding Z; Ma M; Zhong C; Wang S; Fu Z; Hou Y; Liu Y; Zhong L; Chu Y; Li F; Song C; Wang Y; Yang J; Li W
Bioorg Med Chem; 2020 Jan; 28(1):115186. PubMed ID: 31759826
[TBL] [Abstract][Full Text] [Related]
7. Anti-microtubule 'plinabulin' chemical probe KPU-244-B3 labeled both alpha- and beta-tubulin.
Yamazaki Y; Sumikura M; Hidaka K; Yasui H; Kiso Y; Yakushiji F; Hayashi Y
Bioorg Med Chem; 2010 May; 18(9):3169-74. PubMed ID: 20395148
[TBL] [Abstract][Full Text] [Related]
8. Design, synthesis and biological evaluation of anti-pancreatic cancer activity of plinabulin derivatives based on the co-crystal structure.
Fu Z; Hou Y; Ji C; Ma M; Tian Z; Deng M; Zhong L; Chu Y; Li W
Bioorg Med Chem; 2018 May; 26(8):2061-2072. PubMed ID: 29571653
[TBL] [Abstract][Full Text] [Related]
9. Structures of a diverse set of colchicine binding site inhibitors in complex with tubulin provide a rationale for drug discovery.
Wang Y; Zhang H; Gigant B; Yu Y; Wu Y; Chen X; Lai Q; Yang Z; Chen Q; Yang J
FEBS J; 2016 Jan; 283(1):102-11. PubMed ID: 26462166
[TBL] [Abstract][Full Text] [Related]
10. Unambiguous Identification of β-Tubulin as the Direct Cellular Target Responsible for the Cytotoxicity of Chalcone by Photoaffinity Labeling.
Zhou B; Yu X; Zhuang C; Villalta P; Lin Y; Lu J; Xing C
ChemMedChem; 2016 Jul; 11(13):1436-45. PubMed ID: 27203512
[TBL] [Abstract][Full Text] [Related]
11. Tubulin colchicine binding site inhibitors as vascular disrupting agents in clinical developments.
Ji YT; Liu YN; Liu ZP
Curr Med Chem; 2015; 22(11):1348-60. PubMed ID: 25620094
[TBL] [Abstract][Full Text] [Related]
12. NPI-2358 is a tubulin-depolymerizing agent: in-vitro evidence for activity as a tumor vascular-disrupting agent.
Nicholson B; Lloyd GK; Miller BR; Palladino MA; Kiso Y; Hayashi Y; Neuteboom ST
Anticancer Drugs; 2006 Jan; 17(1):25-31. PubMed ID: 16317287
[TBL] [Abstract][Full Text] [Related]
13. Design and Synthesis of Novel Phenylahistin Derivatives Based on Co-Crystal Structures as Potent Microtubule Inhibitors for Anti-Cancer Therapy.
Ding Z; Li F; Xie L; Gu M; Li C; Liu C; Peng C; Li W
Mar Drugs; 2022 Nov; 20(12):. PubMed ID: 36547899
[TBL] [Abstract][Full Text] [Related]
14. Structure-based design and synthesis of novel furan-diketopiperazine-type derivatives as potent microtubule inhibitors for treating cancer.
Ding Z; Li F; Zhong C; Li F; Liu Y; Wang S; Zhao J; Li W
Bioorg Med Chem; 2020 May; 28(10):115435. PubMed ID: 32278711
[TBL] [Abstract][Full Text] [Related]
15. Design, synthesis and anti-tumor evaluation of plinabulin derivatives as potential agents targeting β-tubulin.
Fang S; Bi S; Li Y; Tian S; Xu H; Fu L; Wang S; Tang Y; Qiu P
Bioorg Med Chem Lett; 2023 Jul; 91():129370. PubMed ID: 37301522
[TBL] [Abstract][Full Text] [Related]
16. Discovery of novel 2-phenyl-imidazo[1,2-a]pyridine analogues targeting tubulin polymerization as antiproliferative agents.
An W; Wang W; Yu T; Zhang Y; Miao Z; Meng T; Shen J
Eur J Med Chem; 2016 Apr; 112():367-372. PubMed ID: 26927488
[TBL] [Abstract][Full Text] [Related]
17. 1-Phenyl-dihydrobenzoindazoles as novel colchicine site inhibitors: Structural basis and antitumor efficacy.
Jiang J; Zhang H; Wang C; Zhang Q; Fang S; Zhou R; Hu J; Zhu J; Zhou Y; Luo C; Zheng C
Eur J Med Chem; 2019 Sep; 177():448-456. PubMed ID: 31174062
[TBL] [Abstract][Full Text] [Related]
18. Antivascular and antitumor properties of the tubulin-binding chalcone TUB091.
Canela MD; Noppen S; Bueno O; Prota AE; Bargsten K; Sáez-Calvo G; Jimeno ML; Benkheil M; Ribatti D; Velázquez S; Camarasa MJ; Díaz JF; Steinmetz MO; Priego EM; Pérez-Pérez MJ; Liekens S
Oncotarget; 2017 Feb; 8(9):14325-14342. PubMed ID: 27224920
[TBL] [Abstract][Full Text] [Related]
19. Polymorphs, co-crystal structure and pharmacodynamics study of MBRI-001, a deuterium-substituted plinabulin derivative as a tubulin polymerization inhibitor.
Ma M; Ding Z; Wang S; Ma L; Wang Y; Zhong L; Li Z; Yang J; Li W
Bioorg Med Chem; 2019 May; 27(9):1836-1844. PubMed ID: 30910474
[TBL] [Abstract][Full Text] [Related]
20. Water-soluble prodrug of antimicrotubule agent plinabulin: effective strategy with click chemistry.
Yakushiji F; Tanaka H; Muguruma K; Iwahashi T; Yamazaki Y; Hayashi Y
Chemistry; 2011 Nov; 17(45):12587-90. PubMed ID: 21956869
[No Abstract] [Full Text] [Related]
[Next] [New Search]
