115 related articles for article (PubMed ID: 24005047)
21. Drug binding to aromatic residues in the HERG channel pore cavity as possible explanation for acquired Long QT syndrome by antiparkinsonian drug budipine.
Scholz EP; Zitron E; Kiesecker C; Lueck S; Kathöfer S; Thomas D; Weretka S; Peth S; Kreye VA; Schoels W; Katus HA; Kiehn J; Karle CA
Naunyn Schmiedebergs Arch Pharmacol; 2003 Nov; 368(5):404-14. PubMed ID: 14557918
[TBL] [Abstract][Full Text] [Related]
22. Inhibition of cardiac HERG currents by the DNA topoisomerase II inhibitor amsacrine: mode of action.
Thomas D; Hammerling BC; Wu K; Wimmer AB; Ficker EK; Kirsch GE; Kochan MC; Wible BA; Scholz EP; Zitron E; Kathöfer S; Kreye VA; Katus HA; Schoels W; Karle CA; Kiehn J
Br J Pharmacol; 2004 Jun; 142(3):485-94. PubMed ID: 15148258
[TBL] [Abstract][Full Text] [Related]
23. Direct block of hERG potassium channels by the protein kinase C inhibitor bisindolylmaleimide I (GF109203X).
Thomas D; Hammerling BC; Wimmer AB; Wu K; Ficker E; Kuryshev YA; Scherer D; Kiehn J; Katus HA; Schoels W; Karle CA
Cardiovasc Res; 2004 Dec; 64(3):467-76. PubMed ID: 15537500
[TBL] [Abstract][Full Text] [Related]
24. Inhibition of the HERG K+ channel by the antifungal drug ketoconazole depends on channel gating and involves the S6 residue F656.
Ridley JM; Milnes JT; Duncan RS; McPate MJ; James AF; Witchel HJ; Hancox JC
FEBS Lett; 2006 Apr; 580(8):1999-2005. PubMed ID: 16542653
[TBL] [Abstract][Full Text] [Related]
25. Molecular determinants of hERG channel block by terfenadine and cisapride.
Kamiya K; Niwa R; Morishima M; Honjo H; Sanguinetti MC
J Pharmacol Sci; 2008 Nov; 108(3):301-7. PubMed ID: 18987434
[TBL] [Abstract][Full Text] [Related]
26. Block of wild-type and inactivation-deficient human ether-a-go-go-related gene K+ channels by halofantrine.
Sánchez-Chapula JA; Navarro-Polanco RA; Sanguinetti MC
Naunyn Schmiedebergs Arch Pharmacol; 2004 Dec; 370(6):484-91. PubMed ID: 15558243
[TBL] [Abstract][Full Text] [Related]
27. H(1) antihistamine drug promethazine directly blocks hERG K(+) channel.
Jo SH; Hong HK; Chong SH; Lee HS; Choe H
Pharmacol Res; 2009 Nov; 60(5):429-37. PubMed ID: 19497368
[TBL] [Abstract][Full Text] [Related]
28. Anticholinergic antiparkinson drug orphenadrine inhibits HERG channels: block attenuation by mutations of the pore residues Y652 or F656.
Scholz EP; Konrad FM; Weiss DL; Zitron E; Kiesecker C; Bloehs R; Kulzer M; Thomas D; Kathöfer S; Bauer A; Maurer MH; Seemann G; Katus HA; Karle CA
Naunyn Schmiedebergs Arch Pharmacol; 2007 Dec; 376(4):275-84. PubMed ID: 17965852
[TBL] [Abstract][Full Text] [Related]
29. Papaverine, a vasodilator, blocks the pore of the HERG channel at submicromolar concentration.
Kim YJ; Hong HK; Lee HS; Moh SH; Park JC; Jo SH; Choe H
J Cardiovasc Pharmacol; 2008 Dec; 52(6):485-93. PubMed ID: 19034039
[TBL] [Abstract][Full Text] [Related]
30. Inhibition of the HERG channel by droperidol depends on channel gating and involves the S6 residue F656.
Luo T; Luo A; Liu M; Liu X
Anesth Analg; 2008 Apr; 106(4):1161-70, table of contents. PubMed ID: 18349188
[TBL] [Abstract][Full Text] [Related]
31. A novel assessment of nefazodone-induced hERG inhibition by electrophysiological and stereochemical method.
Shin DS; Park MJ; Lee HA; Lee JY; Chung HC; Yoo DS; Chae CH; Park SJ; Kim KS; Bae MA
Toxicol Appl Pharmacol; 2014 Feb; 274(3):361-71. PubMed ID: 24374264
[TBL] [Abstract][Full Text] [Related]
32. Block of hERG channel by ziprasidone: biophysical properties and molecular determinants.
Su Z; Chen J; Martin RL; McDermott JS; Cox BF; Gopalakrishnan M; Gintant GA
Biochem Pharmacol; 2006 Jan; 71(3):278-86. PubMed ID: 16325148
[TBL] [Abstract][Full Text] [Related]
33. Multiple mechanisms of hERG liability: K+ current inhibition, disruption of protein trafficking, and apoptosis induced by amoxapine.
Obers S; Staudacher I; Ficker E; Dennis A; Koschny R; Erdal H; Bloehs R; Kisselbach J; Karle CA; Schweizer PA; Katus HA; Thomas D
Naunyn Schmiedebergs Arch Pharmacol; 2010 May; 381(5):385-400. PubMed ID: 20229012
[TBL] [Abstract][Full Text] [Related]
34. Mutational analysis of block and facilitation of HERG current by a class III anti-arrhythmic agent, nifekalant.
Hosaka Y; Iwata M; Kamiya N; Yamada M; Kinoshita K; Fukunishi Y; Tsujimae K; Hibino H; Aizawa Y; Inanobe A; Nakamura H; Kurachi Y
Channels (Austin); 2007; 1(3):198-208. PubMed ID: 18690032
[TBL] [Abstract][Full Text] [Related]
35. Effect of S5P alpha-helix charge mutants on inactivation of hERG K+ channels.
Clarke CE; Hill AP; Zhao J; Kondo M; Subbiah RN; Campbell TJ; Vandenberg JI
J Physiol; 2006 Jun; 573(Pt 2):291-304. PubMed ID: 16556651
[TBL] [Abstract][Full Text] [Related]
36. Anesthetic drug midazolam inhibits cardiac human ether-à-go-go-related gene channels: mode of action.
Vonderlin N; Fischer F; Zitron E; Seyler C; Scherer D; Thomas D; Katus HA; Scholz EP
Drug Des Devel Ther; 2015; 9():867-77. PubMed ID: 25733807
[TBL] [Abstract][Full Text] [Related]
37. Inhibition of human ether-a-go-go-related gene potassium channels by alpha 1-adrenoceptor antagonists prazosin, doxazosin, and terazosin.
Thomas D; Wimmer AB; Wu K; Hammerling BC; Ficker EK; Kuryshev YA; Kiehn J; Katus HA; Schoels W; Karle CA
Naunyn Schmiedebergs Arch Pharmacol; 2004 May; 369(5):462-72. PubMed ID: 15098086
[TBL] [Abstract][Full Text] [Related]
38. Molecular interaction of droperidol with human ether-a-go-go-related gene channels: prolongation of action potential duration without inducing early afterdepolarization.
Schwoerer AP; Blütner C; Brandt S; Binder S; Siebrands CC; Ehmke H; Friederich P
Anesthesiology; 2007 May; 106(5):967-76. PubMed ID: 17457128
[TBL] [Abstract][Full Text] [Related]
39. Marine algal toxin azaspiracid is an open-state blocker of hERG potassium channels.
Twiner MJ; Doucette GJ; Rasky A; Huang XP; Roth BL; Sanguinetti MC
Chem Res Toxicol; 2012 Sep; 25(9):1975-84. PubMed ID: 22856456
[TBL] [Abstract][Full Text] [Related]
40. Fluconazole inhibits hERG K(+) channel by direct block and disruption of protein trafficking.
Han S; Zhang Y; Chen Q; Duan Y; Zheng T; Hu X; Zhang Z; Zhang L
Eur J Pharmacol; 2011 Jan; 650(1):138-44. PubMed ID: 20951697
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]