BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

194 related articles for article (PubMed ID: 24008121)

  • 1. Trp266 determines the binding specificity of a porcine aflatoxin B₁ aldehyde reductase for aflatoxin B₁-dialdehyde.
    Wu J; Xu W; Zhang C; Chang Q; Tang X; Li K; Deng Y
    Biochem Pharmacol; 2013 Nov; 86(9):1357-65. PubMed ID: 24008121
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Molecular cloning, expression and catalytic activity of a human AKR7 member of the aldo-keto reductase superfamily: evidence that the major 2-carboxybenzaldehyde reductase from human liver is a homologue of rat aflatoxin B1-aldehyde reductase.
    Ireland LS; Harrison DJ; Neal GE; Hayes JD
    Biochem J; 1998 May; 332 ( Pt 1)(Pt 1):21-34. PubMed ID: 9576847
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Novel homodimeric and heterodimeric rat gamma-hydroxybutyrate synthases that associate with the Golgi apparatus define a distinct subclass of aldo-keto reductase 7 family proteins.
    Kelly VP; Sherratt PJ; Crouch DH; Hayes JD
    Biochem J; 2002 Sep; 366(Pt 3):847-61. PubMed ID: 12071861
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Major differences exist in the function and tissue-specific expression of human aflatoxin B1 aldehyde reductase and the principal human aldo-keto reductase AKR1 family members.
    O'connor T; Ireland LS; Harrison DJ; Hayes JD
    Biochem J; 1999 Oct; 343 Pt 2(Pt 2):487-504. PubMed ID: 10510318
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Quantification of urinary aflatoxin B1 dialdehyde metabolites formed by aflatoxin aldehyde reductase using isotope dilution tandem mass spectrometry.
    Johnson DN; Egner PA; Obrian G; Glassbrook N; Roebuck BD; Sutter TR; Payne GA; Kensler TW; Groopman JD
    Chem Res Toxicol; 2008 Mar; 21(3):752-60. PubMed ID: 18266327
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Reduction of aflatoxin B1 dialdehyde by rat and human aldo-keto reductases.
    Guengerich FP; Cai H; McMahon M; Hayes JD; Sutter TR; Groopman JD; Deng Z; Harris TM
    Chem Res Toxicol; 2001 Jun; 14(6):727-37. PubMed ID: 11409944
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Protection conferred by selenium deficiency against aflatoxin B1 in the rat is associated with the hepatic expression of an aldo-keto reductase and a glutathione S-transferase subunit that metabolize the mycotoxin.
    McLeod R; Ellis EM; Arthur JR; Neal GE; Judah DJ; Manson MM; Hayes JD
    Cancer Res; 1997 Oct; 57(19):4257-66. PubMed ID: 9331086
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Purification from rat liver of a novel constitutively expressed member of the aldo-keto reductase 7 family that is widely distributed in extrahepatic tissues.
    Kelly VP; Ireland LS; Ellis EM; Hayes JD
    Biochem J; 2000 Jun; 348 Pt 2(Pt 2):389-400. PubMed ID: 10816434
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Crystal structure of mouse succinic semialdehyde reductase AKR7A5: structural basis for substrate specificity.
    Zhu X; Lapthorn AJ; Ellis EM
    Biochemistry; 2006 Feb; 45(6):1562-70. PubMed ID: 16460003
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Protection against aflatoxin B1-induced cytotoxicity by expression of the cloned aflatoxin B1-aldehyde reductases rat AKR7A1 and human AKR7A3.
    Bodreddigari S; Jones LK; Egner PA; Groopman JD; Sutter CH; Roebuck BD; Guengerich FP; Kensler TW; Sutter TR
    Chem Res Toxicol; 2008 May; 21(5):1134-42. PubMed ID: 18416522
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Dealing with aflatoxin B1 dihydrodiol acute effects: Impact of aflatoxin B1-aldehyde reductase enzyme activity in poultry species tolerant to AFB1 toxic effects.
    Murcia H; Diaz GJ
    PLoS One; 2020; 15(6):e0235061. PubMed ID: 32569334
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Substrate specificity of an aflatoxin-metabolizing aldehyde reductase.
    Ellis EM; Hayes JD
    Biochem J; 1995 Dec; 312 ( Pt 2)(Pt 2):535-41. PubMed ID: 8526867
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Resistance to aflatoxin B1 is associated with the expression of a novel aldo-keto reductase which has catalytic activity towards a cytotoxic aldehyde-containing metabolite of the toxin.
    Hayes JD; Judah DJ; Neal GE
    Cancer Res; 1993 Sep; 53(17):3887-94. PubMed ID: 8395332
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Bioactivation and Regioselectivity of Pig Cytochrome P450 3A29 towards Aflatoxin B₁.
    Wu J; Chen R; Zhang C; Li K; Xu W; Wang L; Chen Q; Mu P; Jiang J; Wen J; Deng Y
    Toxins (Basel); 2016 Sep; 8(9):. PubMed ID: 27626447
    [TBL] [Abstract][Full Text] [Related]  

  • 15. cDNA cloning, expression and activity of a second human aflatoxin B1-metabolizing member of the aldo-keto reductase superfamily, AKR7A3.
    Knight LP; Primiano T; Groopman JD; Kensler TW; Sutter TR
    Carcinogenesis; 1999 Jul; 20(7):1215-23. PubMed ID: 10383892
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Cloning, expression and functional characterization of cytochrome P450 3A37 from turkey liver with high aflatoxin B1 epoxidation activity.
    Rawal S; Yip SS; Coulombe RA
    Chem Res Toxicol; 2010 Aug; 23(8):1322-9. PubMed ID: 20707407
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Genetic variation of Aflatoxin B1 aldehyde reductase genes (AFAR) in human tumour cells.
    Praml C; Schulz W; Claas A; Mollenhauer J; Poustka A; Ackermann R; Schwab M; Henrich KO
    Cancer Lett; 2008 Dec; 272(1):160-6. PubMed ID: 18752886
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Cloning and expression of succinic semialdehyde reductase from human brain. Identity with aflatoxin B1 aldehyde reductase.
    Schaller M; Schaffhauser M; Sans N; Wermuth B
    Eur J Biochem; 1999 Nov; 265(3):1056-60. PubMed ID: 10518801
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Transgenic expression of aflatoxin aldehyde reductase (AKR7A1) modulates aflatoxin B1 metabolism but not hepatic carcinogenesis in the rat.
    Roebuck BD; Johnson DN; Sutter CH; Egner PA; Scholl PF; Friesen MD; Baumgartner KJ; Ware NM; Bodreddigari S; Groopman JD; Kensler TW; Sutter TR
    Toxicol Sci; 2009 May; 109(1):41-9. PubMed ID: 19168568
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Reaction of aflatoxin B(1) oxidation products with lysine.
    Guengerich FP; Arneson KO; Williams KM; Deng Z; Harris TM
    Chem Res Toxicol; 2002 Jun; 15(6):780-92. PubMed ID: 12067245
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.