BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

201 related articles for article (PubMed ID: 24012181)

  • 1. Synthesis and biological evaluation of novel 3,4-diaryl lactam derivatives as triple reuptake inhibitors.
    Park JE; Song C; Choi K; Sim T; Moon B; Roh EJ
    Bioorg Med Chem Lett; 2013 Oct; 23(20):5515-8. PubMed ID: 24012181
    [TBL] [Abstract][Full Text] [Related]  

  • 2. 4-Phenyl tetrahydroisoquinolines as dual norepinephrine and dopamine reuptake inhibitors.
    Pechulis AD; Beck JP; Curry MA; Wolf MA; Harms AE; Xi N; Opalka C; Sweet MP; Yang Z; Vellekoop AS; Klos AM; Crocker PJ; Hassler C; Laws M; Kitchen DB; Smith MA; Olson RE; Liu S; Molino BF
    Bioorg Med Chem Lett; 2012 Dec; 22(23):7219-22. PubMed ID: 23084899
    [TBL] [Abstract][Full Text] [Related]  

  • 3. 1-Heteroaryl-6-(3,4-dichlorophenyl)-3-azabicyclo[4.1.0]heptane: further insights into a class of triple re-uptake inhibitors.
    Micheli F; Cavanni P; Bettati M; Bonanomi G; Di Fabio R; Fazzolari E; Marchioro C; Roscic M; Tarsi L; Visentini F; Zonzini L; Worby A
    Bioorg Med Chem; 2011 Jun; 19(11):3451-61. PubMed ID: 21550808
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Pharmacological and behavioral characterization of D-473, an orally active triple reuptake inhibitor targeting dopamine, serotonin and norepinephrine transporters.
    Dutta AK; Santra S; Sharma H; Voshavar C; Xu L; Mabrouk O; Antonio T; Reith ME
    PLoS One; 2014; 9(11):e113420. PubMed ID: 25427177
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Synthesis, monoamine transporter binding, properties, and functional monoamine uptake activity of 3beta-[4-methylphenyl and 4-chlorophenyl]-2 beta-[5-(substituted phenyl)thiazol-2-yl]tropanes.
    Gong PK; Blough BE; Brieaddy LE; Huang X; Kuhar MJ; Navarro HA; Carroll FI
    J Med Chem; 2007 Jul; 50(15):3686-95. PubMed ID: 17602602
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Structure-activity relationships of the 1-amino-3-(1H-indol-1-yl)-3-phenylpropan-2-ol series of monoamine reuptake inhibitors.
    Mahaney PE; Kim CY; Coghlan RD; Cohn ST; Heffernan GD; Huselton CA; Terefenko EA; Vu AT; Zhang P; Burroughs KD; Cosmi SA; Bray JA; Johnston GH; Deecher DC; Trybulski EJ
    Bioorg Med Chem Lett; 2009 Oct; 19(19):5807-10. PubMed ID: 19713106
    [TBL] [Abstract][Full Text] [Related]  

  • 7. 1-(4-Methylphenyl)-2-pyrrolidin-1-yl-pentan-1-one (Pyrovalerone) analogues: a promising class of monoamine uptake inhibitors.
    Meltzer PC; Butler D; Deschamps JR; Madras BK
    J Med Chem; 2006 Feb; 49(4):1420-32. PubMed ID: 16480278
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Design and synthesis of promiscuous high-affinity monoamine transporter ligands: unraveling transporter selectivity.
    Greiner E; Boos TL; Prisinzano TE; De Martino MG; Zeglis B; Dersch CM; Marcus J; Partilla JS; Rothman RB; Jacobson AE; Rice KC
    J Med Chem; 2006 Mar; 49(5):1766-72. PubMed ID: 16509591
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Design and optimisation of selective serotonin re-uptake inhibitors with high synthetic accessibility: part 2.
    Andrews M; Brown A; Chiva JY; Fradet D; Gordon D; Lansdell M; MacKenny M
    Bioorg Med Chem Lett; 2009 Oct; 19(20):5893-7. PubMed ID: 19740658
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Syntheses and binding studies of new [(aryl)(aryloxy)methyl]piperidine derivatives and related compounds as potential antidepressant drugs with high affinity for serotonin (5-HT) and norepinephrine (NE) transporters.
    Orjales A; Mosquera R; Toledo A; Pumar MC; García N; Cortizo L; Labeaga L; Innerárity A
    J Med Chem; 2003 Dec; 46(25):5512-32. PubMed ID: 14640559
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Discovery of 1-(3,4-dichlorophenyl)-N,N-dimethyl-1,2,3,4-tetrahydroquinolin-4-amine, a dual serotonin and dopamine reuptake inhibitor.
    Shao L; Ma J; Wang F; Malcolm SC; Hewitt MC; Campbell UC; Spicer NA; Hardy LW; Schreiber R; Spear KL; Varney MA
    Bioorg Med Chem Lett; 2011 Jan; 21(1):520-3. PubMed ID: 21095126
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Recent advances in the understanding of the interaction of antidepressant drugs with serotonin and norepinephrine transporters.
    Andersen J; Kristensen AS; Bang-Andersen B; Strømgaard K
    Chem Commun (Camb); 2009 Jul; (25):3677-92. PubMed ID: 19557250
    [TBL] [Abstract][Full Text] [Related]  

  • 13. D-161, a novel pyran-based triple monoamine transporter blocker: behavioral pharmacological evidence for antidepressant-like action.
    Dutta AK; Ghosh B; Biswas S; Reith ME
    Eur J Pharmacol; 2008 Jul; 589(1-3):73-9. PubMed ID: 18561912
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Synthesis and biological evaluation of bupropion analogues as potential pharmacotherapies for cocaine addiction.
    Carroll FI; Blough BE; Abraham P; Mills AC; Holleman JA; Wolckenhauer SA; Decker AM; Landavazo A; McElroy KT; Navarro HA; Gatch MB; Forster MJ
    J Med Chem; 2009 Nov; 52(21):6768-81. PubMed ID: 19821577
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Benzothienyloxy phenylpropanamines, novel dual inhibitors of serotonin and norepinephrine reuptake.
    Boot JR; Brace G; Delatour CL; Dezutter N; Fairhurst J; Findlay J; Gallagher PT; Hoes I; Mahadevan S; Mitchell SN; Rathmell RE; Richards SJ; Simmonds RG; Wallace L; Whatton MA
    Bioorg Med Chem Lett; 2004 Nov; 14(21):5395-9. PubMed ID: 15454233
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The synthesis and biological evaluation of 2-(3-methyl or 3-phenylisoxazol-5-yl)-3-aryl-8-thiabicyclo[3.2.1]octanes.
    Purushotham M; Sheri A; Pham-Huu DP; Madras BK; Janowsky A; Meltzer PC
    Bioorg Med Chem Lett; 2011 Jan; 21(1):48-51. PubMed ID: 21146984
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Potential antidepressants displayed combined alpha(2)-adrenoceptor antagonist and monoamine uptake inhibitor properties.
    Cordi AA; Berque-Bestel I; Persigand T; Lacoste JM; Newman-Tancredi A; Audinot V; Millan MJ
    J Med Chem; 2001 Mar; 44(5):787-805. PubMed ID: 11262089
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Discovery of a new series of monoamine reuptake inhibitors, the 1-amino-3-(1H-indol-1-yl)-3-phenylpropan-2-ols.
    Kim CY; Mahaney PE; McConnell O; Zhang Y; Manas E; Ho DM; Deecher DC; Trybulski EJ
    Bioorg Med Chem Lett; 2009 Sep; 19(17):5029-32. PubMed ID: 19632110
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Development of potent dopamine-norepinephrine uptake inhibitors (DNRIs) based on a (2S,4R,5R)-2-benzhydryl-5-((4-methoxybenzyl)amino)tetrahydro-2H-pyran-4-ol molecular template.
    Santra S; Sharma H; Vedachalam S; Antonio T; Reith M; Dutta A
    Bioorg Med Chem; 2015 Feb; 23(4):821-8. PubMed ID: 25593099
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Further SAR studies of piperidine-based analogues of cocaine. 2. Potent dopamine and serotonin reuptake inhibitors.
    Tamiz AP; Zhang J; Flippen-Anderson JL; Zhang M; Johnson KM; Deschaux O; Tella S; Kozikowski AP
    J Med Chem; 2000 Mar; 43(6):1215-22. PubMed ID: 10737754
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.